Compound Summary
Tyrphostin 47
Compound Information
Tyrphostin 47
Compound Name: | Tyrphostin 47 |
Compound CID: | 667601 |
Synonyms: | Tyrphostin 47 Tyrphostin A47 AG 213 AG-213 118409-60-2 More... |
Iupac Name: | (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide |
InChI: | InChI=1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+ |
InChIKey: | ZGHQGWOETPXKLY-XVNBXDOJSA-N |
Canonical Smiles: | C1=CC(=C(C=C1C=C(C#N)C(=S)N)O)O |
Isomeric Smiles: | C1=CC(=C(C=C1/C=C(\C#N)/C(=S)N)O)O |
Molecular Weight: | 220.25 |
Molecular Formula: | C10H8N2O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin 47
Molecular Weight: | 220.25 |
Molecular Formula: | C10H8N2O2S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 15 |
Complexity: | 332 |
Synonyms
Tyrphostin 47
| Tyrphostin 47 | Tyrphostin 47 |
|---|---|
Tyrphostin 47 |
Tyrphostin A47 |
AG 213 |
AG-213 |
118409-60-2 |
122520-86-9 |
RG-50864 |
3,4-Dihydroxy-alpha-cyanothiocinnamamide |
RG 50864 |
alpha-Cyano-(3,4-dihydroxy)thiocinnamide |
CHEMBL77030 |
2-Propenethioamide, 2-cyano-3-(3,4-dihydroxyphenyl)- |
(E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide |
tyrphostin AG213 |
Tyrphostin AG-213 |
Tyrphostin RG50864 |
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide |
2-Propenethioamide, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- |
3,4-Dihydroxy-alpha-cyanothiocinnamide |
RG50864 |
alpha-Cyano-3,4-dihydroxythiocinnamamide |
AG213 |
3,4-Dihydroxybenzylidenethioacetamide |
Tyrphostin A-47 |
2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenethioamide |
Tocris-0503 |
BiomolKI_000014 |
Lopac-T-7540 |
BiomolKI2_000024 |
AG213 (Tyrphostin 47) |
BMK1-C2 |
BSPBio_001392 |
SCHEMBL239295 |
T7540 (Tyrphostin 47) |
BDBM4363 |
SCHEMBL14411466 |
CHEBI:93703 |
DTXSID701018041 |
HMS1361F14 |
HMS1791F14 |
HMS1989F14 |
HMS3402F14 |
ZINC3871430 |
2087AH |
NSC638083 |
AG-213 AG 213 |
CCG-100618 |
NSC-638083 |
IDI1_033862 |
NCGC00016050-01 |
NCGC00016050-02 |
NCGC00016050-03 |
NCGC00016050-04 |
NCGC00016050-05 |
NCGC00016050-06 |
NCGC00024619-01 |
NCGC00024619-02 |
NCGC00024619-03 |
NCGC00024619-04 |
benzylidenemalononitrile (BMN) deriv. 47 |
2-Cyano-3-(3,4-dihydroxy-phenyl)-thioacrylamide |
409A602 |
SR-01000597611 |
SR-01000597611-1 |
BRD-K96778649-001-01-6 |
Experimental Data
Tyrphostin 47
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 10.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin 47
Statistics Data
Tyrphostin 47
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | 1 | 1 |
Statistics Data Visualization
Tyrphostin 47
