Compound Summary
Tyrphostin 23
Compound Information
Tyrphostin 23
Compound Name: | Tyrphostin 23 |
Compound CID: | 2052 |
Synonyms: | Tyrphostin 23 118409-57-7 Tyrphostin A23 AG 18 RG-50810 More... |
Iupac Name: | 2-[(3,4-dihydroxyphenyl)methylidene]propanedinitrile |
InChI: | InChI=1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H |
InChIKey: | VTJXFTPMFYAJJU-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=C(C=C1C=C(C#N)C#N)O)O |
Isomeric Smiles: | C1=CC(=C(C=C1C=C(C#N)C#N)O)O |
Molecular Weight: | 186.17 |
Molecular Formula: | C10H6N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin 23
Molecular Weight: | 186.17 |
Molecular Formula: | C10H6N2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 14 |
Complexity: | 313 |
Synonyms
Tyrphostin 23
| Tyrphostin 23 | Tyrphostin 23 |
|---|---|
Tyrphostin 23 |
118409-57-7 |
Tyrphostin A23 |
AG 18 |
RG-50810 |
(3,4-Dihydroxybenzylidene)malononitrile |
AG-18 |
2-(3,4-dihydroxybenzylidene)malononitrile |
2-(3,4-dihydroxyphenyl)methylidenepropanedinitrile |
ag18 |
UNII-RV0GCD31OJ |
alpha-Cyano-(3,4-dihydroxy)cinnamonitrile |
Propanedinitrile,2-(3,4-dihydroxyphenyl)methylene- |
AG-18 (Tyrphostin 23) |
RV0GCD31OJ |
MFCD00133899 |
Tyrphostin AG18 |
NCGC00016043-03 |
(3,4-dihydroxybenzylidene)propanedinitrile |
Tyrphostin RG50810 |
DSSTox_CID_25215 |
DSSTox_RID_80754 |
DSSTox_GSID_45215 |
2-(3,4-dihydroxyphenyl)methylene-propanedinitrile |
CAS-118409-57-7 |
RG 50810 |
SR-01000075506 |
(3,4-Dihydroxyphenyl)methylene propanedinitrile |
tyrphostin-23 |
tyrphostin-AG-18 |
Tocris-0493 |
ACMC-20dhi7 |
BiomolKI_000011 |
Lopac-T-7165 |
BiomolKI2_000021 |
cid_2052 |
Lopac0_001160 |
Oprea1_072726 |
AG 18 (Tyrphostin 23) |
Tyrphostin 23, >=98% |
MLS002153315 |
CHEMBL76904 |
SCHEMBL241922 |
Propanedinitrile, ((3,4-dihydroxyphenyl)methylene)- |
BDBM4339 |
BMK1-B11 |
DTXSID9045215 |
CHEBI:92862 |
ZINC15331 |
AOB5120 |
EX-A901 |
HMS2233I22 |
HMS3263H21 |
HMS3266E18 |
HMS3369M02 |
HMS3414G15 |
HMS3653D19 |
HMS3678G15 |
BCP06838 |
Tox21_110287 |
Tox21_501160 |
2085AH |
2773AH |
3-HYDROXY-5-NITROBENZOICACID |
BBL008106 |
HSCI1_000108 |
MCK100778 |
s8009 |
STL139213 |
TX 825 |
3,4-Dihydroxybenzylidene malononitrile |
AKOS005715658 |
Tox21_110287_1 |
AG18;Tyrphostin 23; RG-50810 |
CCG-100615 |
CS-1387 |
LP01160 |
MCULE-8159081339 |
SDCCGSBI-0051127.P002 |
3,4-(Dihydroxybenzylidene)malononitrile |
NCGC00016043-01 |
NCGC00016043-02 |
NCGC00016043-04 |
NCGC00016043-05 |
NCGC00016043-06 |
NCGC00016043-07 |
NCGC00016043-08 |
NCGC00016043-17 |
NCGC00024615-01 |
NCGC00024615-02 |
NCGC00024615-03 |
NCGC00024615-04 |
NCGC00261845-01 |
AC-30286 |
AS-69033 |
benzylidenemalononitrile (BMN) deriv. 23 |
HY-15644 |
SMR001230729 |
AB0152128 |
DB-093180 |
2-(3,4-Dihydroxy-benzylidene)-malononitrile |
EU-0101160 |
FT-0675716 |
SW219523-1 |
T3503 |
EC-000.2086 |
T 7165 |
((3,4-Dihydroxyphenyl)methylene)-Propanedinitrile |
(3,4-Dihydroxyphenyl)methylene-propenedinitrile |
AG 18 - CAS 118409-57-7 |
J-003744 |
SR-01000075506-1 |
SR-01000075506-3 |
SR-01000075506-6 |
BRD-K49657628-001-02-3 |
BRD-K49657628-001-03-1 |
BRD-K49657628-001-05-6 |
Q27164614 |
F6782-3631 |
Experimental Data
Tyrphostin 23
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -6.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin 23
Statistics Data
Tyrphostin 23
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6.000000000000000 | 1 | 1 |
Statistics Data Visualization
Tyrphostin 23
