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Compound Summary

Tyr-Ala

Compound Information

Tyr-Ala

Compound Name:	Tyr-Ala
Compound CID:	5496455
Synonyms:	Tyr-Ala 730-08-5 H-TYR-ALA-OH Tyrosyl-Alanine L-tyrosyl-L-alanine More...
Iupac Name:	(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoic acid
InChI:	InChI=1S/C12H16N2O4/c1-7(12(17)18)14-11(16)10(13)6-8-2-4-9(15)5-3-8/h2-5,7,10,15H,6,13H2,1H3,(H,14,16)(H,17,18)/t7-,10-/m0/s1
InChIKey:	NLKUJNGEGZDXGO-XVKPBYJWSA-N
Canonical Smiles:	CC(C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)N
Isomeric Smiles:	C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)N
Molecular Weight:	252.27
Molecular Formula:	C12H16N2O4

Compound Structure

2D Structure:

3D Structure:

Computed Properties

Tyr-Ala

Molecular Weight:	252.27
Molecular Formula:	C12H16N2O4
Hydrogen Bond Donor Count:	4
Hydrogen Bond Acceptor Count:	5
Rotatable Bond Count:	5
Heavy Atom Count:	18
Complexity:	301

Synonyms

Tyr-Ala

Tyr-Ala	Tyr-Ala
Tyr-Ala	730-08-5
H-TYR-ALA-OH	Tyrosyl-Alanine
L-tyrosyl-L-alanine	(S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)propanoic acid
CHEMBL316103	CHEBI:74879
(2S)-2-(2S)-2-amino-3-(4-hydroxyphenyl)propanoylaminopropanoic acid	L-Alanine, L-tyrosyl-, monomer
L-Alanine, L-tyrosyl-	Tyr-Ala-OH
L-Tyr-L-Ala	SCHEMBL238988
YA	ZINC2566273
BDBM50169129	MFCD00020398
AKOS010420474	Melanin synthesized from Tyr-Ala substrate catalyzed by tyrosinase for 40 hrs
AS-76452	Q27144989
(S)-2-(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino-propionic acid	Melanin synthesized from Tyr-Ala substrate catalyzed by tyrosinase, brominated with N-bromosuccinimide
Melanin synthesized from Tyr-Ala substrate catalyzed by tyrosinase, sulfonated using sulfur trioxide/DMF complex for 1.5-7 hours

Experimental Data

Tyr-Ala

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	10.000000000000000	mM			12.430000000000000			13.040000000000000	S	N2	33683565	Active
Caenorhabditis elegans	1.000000000000000	mM			10.370000000000000			13.040000000000000	S	N2	33683565	Active
Caenorhabditis elegans	1.000000000000000	mM	16.970000000000000	19.170000000000000	12.960000000000000	23.000000000000000	25.000000000000000	0.090000000000000	S	N2	26987062	Active
Caenorhabditis elegans	10.000000000000000	mM	16.980000000000000	19.090000000000000	12.430000000000000	23.000000000000000	26.000000000000000	0.130000000000000	S	N2	26987062	Active
Caenorhabditis elegans	1.000000000000000	mM	17.050000000000000	19.050000000000000	11.730000000000000	23.000000000000000	26.000000000000000	0.130000000000000	S	N2	26987062	Active
Caenorhabditis elegans	10.000000000000000	mM	16.970000000000000	19.230000000000000	13.320000000000000	23.000000000000000	26.000000000000000	0.130000000000000	S	N2	26987062	Active
Caenorhabditis elegans	1.000000000000000	mM	16.980000000000000	18.740000000000000	10.370000000000000	23.000000000000000	26.000000000000000	0.130000000000000	S	N2	26987062	Active
Caenorhabditis elegans	1.000000000000000	mM	16.920000000000000	18.030000000000000	6.560000000000000	23.000000000000000	26.000000000000000	0.130000000000000	S	N2	26987062	Active
Caenorhabditis elegans	10.000000000000000	mM	16.920000000000000	19.280000000000000	13.950000000000000	23.000000000000000	25.000000000000000	0.090000000000000	S	N2	26987062	Active
Caenorhabditis elegans	10.000000000000000	mM	17.050000000000000	18.760000000000000	10.030000000000000	23.000000000000000	25.000000000000000	0.090000000000000	S	N2	26987062	Active

Experimental Data Visualization

Tyr-Ala

Statistics Data

Tyr-Ala

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	13.950000000000000	13.040000000000000	2	10

Statistics Data Visualization

Tyr-Ala

Compound Name:

Tyr-Ala

Compound CID:

5496455

Synonyms:

Tyr-Ala 730-08-5 H-TYR-ALA-OH Tyrosyl-Alanine L-tyrosyl-L-alanine More...

Iupac Name:

(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoic acid

InChI:

InChI=1S/C12H16N2O4/c1-7(12(17)18)14-11(16)10(13)6-8-2-4-9(15)5-3-8/h2-5,7,10,15H,6,13H2,1H3,(H,14,16)(H,17,18)/t7-,10-/m0/s1

InChIKey:

NLKUJNGEGZDXGO-XVKPBYJWSA-N

Canonical Smiles:

CC(C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)N

Isomeric Smiles:

C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)N

Molecular Weight:

252.27

Molecular Formula:

C12H16N2O4

Molecular Weight:

252.27

Molecular Formula:

C12H16N2O4

Hydrogen Bond Donor Count:

4

Hydrogen Bond Acceptor Count:

5

Rotatable Bond Count:

5

Heavy Atom Count:

18

Complexity:

301

Tyr-Ala

730-08-5

H-TYR-ALA-OH

Tyrosyl-Alanine

L-tyrosyl-L-alanine

(S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)propanoic acid

CHEMBL316103

CHEBI:74879

(2S)-2-(2S)-2-amino-3-(4-hydroxyphenyl)propanoylaminopropanoic acid

L-Alanine, L-tyrosyl-, monomer

L-Alanine, L-tyrosyl-

Tyr-Ala-OH

L-Tyr-L-Ala

SCHEMBL238988

YA

ZINC2566273

BDBM50169129

MFCD00020398

AKOS010420474

Melanin synthesized from Tyr-Ala substrate catalyzed by tyrosinase for 40 hrs

AS-76452

Q27144989

(S)-2-(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino-propionic acid

Melanin synthesized from Tyr-Ala substrate catalyzed by tyrosinase, brominated with N-bromosuccinimide

Melanin synthesized from Tyr-Ala substrate catalyzed by tyrosinase, sulfonated using sulfur trioxide/DMF complex for 1.5-7 hours

Tyr-Ala

730-08-5

H-TYR-ALA-OH

Tyrosyl-Alanine

L-tyrosyl-L-alanine

More...