Compound Summary
Thioridazine hydrochloride
Compound Information
Thioridazine hydrochloride
Compound Name: | Thioridazine hydrochloride |
Compound CID: | 66062 |
Synonyms: | Thioridazine hydrochloride 130-61-0 Thioridazine Hcl Sonapax hydrochloride Thioridazine chloride More... |
Iupac Name: | 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine;hydrochloride |
InChI: | InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H |
InChIKey: | NZFNXWQNBYZDAQ-UHFFFAOYSA-N |
Canonical Smiles: | CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl |
Isomeric Smiles: | CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl |
Molecular Weight: | 407 |
Molecular Formula: | C21H27ClN2S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Thioridazine hydrochloride
Molecular Weight: | 407 |
Molecular Formula: | C21H27ClN2S2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 26 |
Complexity: | 432 |
Synonyms
Thioridazine hydrochloride
| Thioridazine hydrochloride | Thioridazine hydrochloride |
|---|---|
Thioridazine hydrochloride |
130-61-0 |
Thioridazine Hcl |
Sonapax hydrochloride |
Thioridazine chloride |
Mellaril hydrochloride |
Aldazine |
Thioridazine (hydrochloride) |
USAF SZ-B |
USAF SZ-3 |
10-2-(1-methylpiperidin-2-yl)ethyl-2-(methylsulfanyl)-10H-phenothiazine hydrochloride |
MLS000028408 |
CHEBI:48566 |
Orsanil |
2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine hydrochloride |
MFCD00012655 |
10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine hydrochloride |
SMR000058380 |
Thioridazine.HCl |
10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylthiophenothiazine hydrochloride |
10-2-(1-methylpiperidin-2-yl)ethyl-2-methylsulfanylphenothiazine;hydrochloride |
Melleril (tablet) |
Melzine |
2-Methylmercapto-10-2-(N-methyl-2-piperidyl)ethylphenothiazine hydrochloride |
NSC186060 |
EINECS 204-992-8 |
NSC 186060 |
Tioridazin |
Metlaril |
C21H27ClN2S2 |
SR-01000000063 |
10-2-(1-Methyl-2-piperidyl)ethyl-2-methylthiophenothiazine hydrochloride |
10-2-(1-Methylpiperidin-2-yl)ethyl-2-(methylthio)-10H-phenothiazine Hydrochloride |
Thioridazine hydrochloride intensol |
Mellaril (TN) |
Prestwick_437 |
10-2-(1-Methyl-2-piperidyl)ethyl-2-(methylthio)-10H-phenothiazine hydrochloride |
Thioridazine hydrochloride USP:JAN |
Thoridazine hydrochloride |
Opera_ID_1713 |
CAS-130-61-0 |
10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine monohydrochloride |
10H-Phenothiazine, 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-, monohydrochloride |
DSSTox_CID_29360 |
DSSTox_RID_83476 |
DSSTox_GSID_49401 |
SCHEMBL41430 |
MLS001148599 |
MLS002222212 |
SPECTRUM1500575 |
CHEMBL1200916 |
DTXSID9049401 |
AOB5375 |
HMS1568O17 |
HMS1921E11 |
Pharmakon1600-01500575 |
BCP19941 |
HY-B0965 |
Thioridazine hydrochloride, >=99% |
Tox21_202801 |
Tox21_501252 |
CCG-39270 |
NSC757349 |
s5563 |
SBB057665 |
AKOS015994763 |
CS-4450 |
KS-5108 |
LP01252 |
MCULE-1090059754 |
NC00594 |
NSC-186060 |
NSC-757349 |
Thioridazine hydrochloride (JP17/USP) |
Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-, monohydrochloride |
NCGC00094492-01 |
NCGC00094492-02 |
NCGC00094492-03 |
NCGC00094492-04 |
NCGC00094492-05 |
NCGC00260347-01 |
NCGC00261937-01 |
I584 |
AB0013772 |
DB-041975 |
EU-0101252 |
FT-0631759 |
FT-0675189 |
ST50412003 |
SW196660-3 |
T3102 |
D00798 |
D82085 |
T 9025 |
22857-EP2295421A1 |
22857-EP2315502A1 |
22857-EP2371810A1 |
22857-EP2371812A1 |
A806110 |
SR-01000000063-2 |
SR-01000000063-7 |
W-108347 |
Q27104616 |
WLN: T C666 BN ISJ ES1 B2-BT6NTJ A1 & GH |
Z2784093622 |
Thioridazine Hydrochloride 1.0 mg/ml in Methanol (as free base) |
10-2-(1-methyl(2-piperidyl))ethyl-2-methylthiophenothiazine, chloride |
Dopamine Receptor Antagonist II, Thioridazine, HCl - CAS 130-61-0 |
Thioridazine hydrochloride, European Pharmacopoeia (EP) Reference Standard |
10-2-(1-Methyl-2-piperidinyl)ethyl-2-(methylthio)-10H-phenothiazine hydrochloride |
Thioridazine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
Experimental Data
Thioridazine hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200.000000000000000 | umol/L | 47.160000000000000 | 45.470000000000000 | -3.570000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 52.830000000000000 | 57.990000000000000 | 9.770000000000000 | S | FEMALES | 33008901 | Active | ||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 31.000000000000000 | S | N2 | 33683565 | Active | ||||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 31.000000000000000 | S | N2 | 24134630 | Active |
Experimental Data Visualization
Thioridazine hydrochloride
Statistics Data
Thioridazine hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 31.000000000000000 | 2 | 2 | |
| Drosophila melanogaster | 9.770000000000000 | 1 | 2 |
Statistics Data Visualization
Thioridazine hydrochloride
