Compound Summary
Thiolactomycin
Compound Information
Thiolactomycin
Compound Name: | Thiolactomycin |
Compound CID: | 135403829 |
Synonyms: | Thiolactomycin Antibiotic 2-200 82079-32-1 (R)-(+)-Thiolactomycin (+)-Thiolactomycin More... |
Iupac Name: | (5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1,3-dienyl]thiophen-2-one |
InChI: | InChI=1S/C11H14O2S/c1-5-7(2)6-11(4)9(12)8(3)10(13)14-11/h5-6,12H,1H2,2-4H3/b7-6+/t11-/m1/s1 |
InChIKey: | SYQNUQSGEWNWKV-XUIVZRPNSA-N |
Canonical Smiles: | CC1=C(C(SC1=O)(C)C=C(C)C=C)O |
Isomeric Smiles: | CC1=C([C@@](SC1=O)(C)/C=C(\C)/C=C)O |
Molecular Weight: | 210.29 |
Molecular Formula: | C11H14O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Thiolactomycin
Molecular Weight: | 210.29 |
Molecular Formula: | C11H14O2S |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 14 |
Complexity: | 352 |
Synonyms
Thiolactomycin
| Thiolactomycin | Thiolactomycin |
|---|---|
Thiolactomycin |
Antibiotic 2-200 |
82079-32-1 |
(R)-(+)-Thiolactomycin |
(+)-Thiolactomycin |
BRN 4423670 |
4-HYDROXY-3,5-DIMETHYL-5-(2-METHYL-BUTA-1,3-DIENYL)-5H-THIOPHEN-2-ONE |
(2R)-5-hydroxy-2,4-dimethyl-2-(1E)-2-methylbuta-1,3-dienylthiophen-3-one |
(R,E)-4-Hydroxy-3,5-dimethyl-5-(2-methylbuta-1,3-dien-1-yl)thiophen-2(5H)-one |
2(5H)-Thiophenone, 3,5-dimethyl-4-hydroxy-5-(2-methyl-1,3-butadienyl)-, (R-(E))- |
TLM |
thiolactomycine |
(5R)-Thiolactomycin |
1fj4 |
2vb8 |
4c6x |
(R)-THIOLACTOMYCIN |
(R-(E))-3,5-Dimethyl-4-hydroxy-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenone |
Lopac0_000908 |
DTXSID6041139 |
SCHEMBL12099108 |
SCHEMBL13332161 |
HMS3262F18 |
ZINC4099011 |
Tox21_500908 |
CCG-204990 |
DB04302 |
LP00908 |
SDCCGSBI-0050883.P002 |
2(5H)-Thiophenone, 4-hydroxy-3,5-dimethyl-5-(2-methyl-1,3-butadienyl)-, (S-(E))- |
NCGC00094221-01 |
NCGC00094221-02 |
NCGC00261593-01 |
EU-0100908 |
T 9567 |
SR-01000076067 |
SR-01000076067-1 |
Q27095124 |
(4-R)(2E,5E)-2,4,6-Trimethyl-3-hydroxy-2,5,7-octatriene-4-thiolide |
(5R)-4-hydroxy-3,5-dimethyl-5-(1E)-2-methylbuta-1,3-dien-1-ylthiophen-2(5H)-one |
(5R)-4-hydroxy-3,5-dimethyl-5-(1E)-2-methylbuta-1,3-dienylthiophen-2-one |
R-(E)-4-Hydroxy-3,5-dimethyl-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenone |
(2R)-5-hydroxy-2,4-dimethyl-2-(1E)-2-methylbuta-1,3-dien-1-yl-2,3-dihydrothiophen-3-one |
Experimental Data
Thiolactomycin
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 2.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Thiolactomycin
Statistics Data
Thiolactomycin
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2.000000000000000 | 1 | 1 |
Statistics Data Visualization
Thiolactomycin
