Compound Summary
Thioflavin T
Compound Information
Thioflavin T
Compound Name: | Thioflavin T |
Compound CID: | 16953 |
Synonyms: | Thioflavin T Thioflavine T 2390-54-7 Basic yellow 1 2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzodthiazol-3-ium chloride More... |
Iupac Name: | 4-(3,6-dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylaniline;chloride |
InChI: | InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1 |
InChIKey: | JADVWWSKYZXRGX-UHFFFAOYSA-M |
Canonical Smiles: | CC1=CC2=C(C=C1)[N+](=C(S2)C3=CC=C(C=C3)N(C)C)C.[Cl-] |
Isomeric Smiles: | CC1=CC2=C(C=C1)[N+](=C(S2)C3=CC=C(C=C3)N(C)C)C.[Cl-] |
Molecular Weight: | 318.9 |
Molecular Formula: | C17H19ClN2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Thioflavin T
Molecular Weight: | 318.9 |
Molecular Formula: | C17H19ClN2S |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 21 |
Complexity: | 325 |
Synonyms
Thioflavin T
| Thioflavin T | Thioflavin T |
|---|---|
Thioflavin T |
Thioflavine T |
2390-54-7 |
Basic yellow 1 |
2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzodthiazol-3-ium chloride |
Setoflavine T |
Acronol Yellow T |
C.I. Basic Yellow 1 |
Tannoflavine T |
Setoflavin T |
Rhoduline Yellow |
Thioflavin TG |
Thioflavine TCN |
Thioflavine TG |
Citroflavine 8G |
Primoflavine 8G |
Thioflavin TCN |
Basic Yellow T |
Purimofurabin 8G |
Thioflavine TCND |
C.I. 49005 |
Acronol Yellow TC |
Methylene Yellow N |
Brilliant Flavine T |
Methylene Yellow NI |
Thioflavin TCN extra |
Acronol Lake Yellow T |
Acronol Lake Yellow TC |
Acronol Yellow TC180 |
Nankai Basic Flavine 8G |
Kansai Basic Flavine 8GO |
MFCD00011944 |
Thioflavine |
Benzothiazolium, 2-4-(dimethylamino)phenyl-3,6-dimethyl-, chloride |
UNII-CAX9SG0II0 |
CAX9SG0II0 |
1326-12-1 |
Methyldehydrothio-p-toluidine sulfonate |
CHEMBL224392 |
CHEBI:76023 |
4-(3,6-dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylaniline chloride |
3,6-Dimethyl-2-dimethylaminophenylbenzothiazolium chloride |
2-4-(DIMETHYLAMINO)PHENYL-3,6-DIMETHYLBENZOTHIAZOLIUM CHLORIDE |
2-4-(dimethylamino)phenyl-3,6-dimethyl-1,3-benzothiazol-3-ium chloride |
Benzothiazolium, 2-4-(dimethylamino)phenyl-3,6-dimethyl-, chloride (1:1) |
2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzothiazolium chloride |
Benzothiazolium, 2-(4-(dimethylamino)phenyl)-3,6-dimethyl-, chloride |
2-4-(Dimethylamino)phenyl-3,6-dimethylbenzodthiazol-3-ium Chloride |
4-(3,6-dimethylbenzothiazol-2-yl)phenyldimethylamine, chloride |
Benzothiazolium, 2-(4-(dimethylamino)phenyl)-3,6-dimethyl-, chloride (1:1) |
EINECS 219-228-9 |
NSC 11235 |
Benzothiazolium, 2-(p-(dimethylamino)phenyl)-3,6-dimethyl-, chloride |
SCHEMBL25298 |
Basic Yellow 1Basic Yellow 1 |
SCHEMBL11428556 |
DTXSID10883841 |
AMY37135 |
HY-D0218 |
NSC11235 |
NSC-11235 |
SBB057655 |
Benzothiazolium,6-dimethyl-, chloride |
AKOS016007447 |
CS-7552 |
CS-W009025 |
MCULE-5464762736 |
Thioflavin T - CAS 2390-54-7 |
Thioflavin T, used as stain for amyloid |
AS-72625 |
BP-30130 |
SY074376 |
FT-0744526 |
ST50308406 |
T0558 |
Z4469 |
O10470 |
T-3730 |
A930157 |
Q2033625 |
2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzo-dthiazol-3-ium chloride |
4-(3,6-dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylaniline;chloride |
2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzodthiazol-3-ium chloride (Thioflavin T) |
Benzothiazolium, 2-(p-(dimethylamino)phenyl)-3,6-dimethyl-, chloride (8CI) |
Experimental Data
Thioflavin T
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 11.000000000000000 | 16.000000000000000 | 0.450000000000000 | S | N2 | 30842997 | Active | ||||
| Caenorhabditis elegans | 500.000000000000000 | umol/L | 11.000000000000000 | 3.500000000000000 | -0.680000000000000 | S | N2 | 30842997 | Inactive | ||||
| Caenorhabditis elegans | 25.000000000000000 | umol/L | 11.000000000000000 | 21.000000000000000 | 0.910000000000000 | S | N2 | 30842997 | Active | ||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 60.000000000000000 | 43.000000000000000 | S | N2 | 21451522 | Active | |||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 18.000000000000000 | 23.000000000000000 | 0.280000000000000 | S | N2 | 31820364 | Active | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 60.000000000000000 | 78.000000000000000 | S | N2 | 21451522 | Active | |||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 11.000000000000000 | 15.000000000000000 | 0.360000000000000 | S | N2 | 30842997 | Active |
Experimental Data Visualization
Thioflavin T
Statistics Data
Thioflavin T
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 60.000000000000000 | 78.000000000000000 | 3 | 7 |
Statistics Data Visualization
Thioflavin T
