Compound Summary
Terazosin hydrochloride
Compound Information
Terazosin hydrochloride
Compound Name: | Terazosin hydrochloride |
Compound CID: | 44383 |
Synonyms: | Terazosin hydrochloride 63074-08-8 Terazosin HCl Hytrin Fosfomic More... |
Iupac Name: | [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone;hydrochloride |
InChI: | InChI=1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H |
InChIKey: | IWSWDOUXSCRCKW-UHFFFAOYSA-N |
Canonical Smiles: | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.Cl |
Isomeric Smiles: | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.Cl |
Molecular Weight: | 423.9 |
Molecular Formula: | C19H26ClN5O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Terazosin hydrochloride
Molecular Weight: | 423.9 |
Molecular Formula: | C19H26ClN5O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 29 |
Complexity: | 544 |
Synonyms
Terazosin hydrochloride
| Terazosin hydrochloride | Terazosin hydrochloride |
|---|---|
Terazosin hydrochloride |
63074-08-8 |
Terazosin HCl |
Hytrin |
Fosfomic |
Zayasel |
Blavin |
Vasocard |
Abbott-45975 |
Terazosin hydrochloride anhydrous |
Flumarc |
(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone hydrochloride |
Terazocin Hydrochloride (anhydrous) |
MLS000040261 |
Terazosin (hydrochloride) |
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride |
SMR000044015 |
DSSTox_CID_25493 |
DSSTox_RID_80913 |
DSSTox_GSID_45493 |
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furanyl)carbonylpiperazine hydrochloride |
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)4-(tetrahydro-2-furanyl)carbonylpiperazine hydrochloride |
CAS-63074-08-8 |
MFCD00467965 |
SR-01000000197 |
Prestwick_146 |
Tetrazosin hydrochloride |
1-(4-amino-6,7-dimethoxy-2-quinazolinyl)4-(tetrahydro-2-furanyl)carbonylpiperazine |
Opera_ID_398 |
NCGC00016903-01 |
SCHEMBL41545 |
Terazosin hydrochloride,pharma |
MLS001077301 |
MLS001305722 |
CHEMBL1256665 |
DTXSID7045493 |
HY-B0371F |
HMS1570G04 |
Pharmakon1600-01505576 |
BCP12795 |
Tox21_110674 |
NSC759168 |
s4679 |
AKOS007930686 |
Tox21_110674_1 |
AC-2074 |
CCG-220751 |
LP01138 |
NSC-759168 |
VA11840 |
NCGC00016026-10 |
NCGC00094404-01 |
NCGC00094404-02 |
DS-11401 |
DB-018541 |
CS-0013075 |
EU-0101138 |
FT-0605647 |
T2751 |
V1531 |
D11585 |
D70611 |
T 4680 |
Terazosin hydrochloride, >=98% (TLC), powder |
074T088 |
SR-01000000197-2 |
SR-01000000197-4 |
Q27270906 |
SR-01000000197-12 |
1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine hydrochloride |
1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride |
24-(Tetrahydro-2-furoy1)piperazinyl-4-amino-6,7-dimethoxyquinazoline hydrochloride |
4-Amino-6,7-dimethoxy-2-4-(tetrahydro-2-furoyl)-1-piperazinylquinazoline Hydrochloride |
4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl-(oxolan-2-yl)methanone;hydrochloride |
4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl-(oxolan-2-yl)methanone;hydron;chloride |
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furanyl)carbonyl-piperazine hydrochloride |
Piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furanyl)carbonyl-, monohydrochloride |
Experimental Data
Terazosin hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -5.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Terazosin hydrochloride
Statistics Data
Terazosin hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5.000000000000000 | 1 | 1 |
Statistics Data Visualization
Terazosin hydrochloride
