Compound Summary
TG003
Compound Information
TG003
Compound Name: | TG003 |
Compound CID: | 1893668 |
Synonyms: | TG003 TG-003 300801-52-9 TG 003 (Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one More... |
Iupac Name: | (1Z)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one |
InChI: | InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7- |
InChIKey: | BGVLELSCIHASRV-QPEQYQDCSA-N |
Canonical Smiles: | CCN1C2=C(C=CC(=C2)OC)SC1=CC(=O)C |
Isomeric Smiles: | CCN\1C2=C(C=CC(=C2)OC)S/C1=C\C(=O)C |
Molecular Weight: | 249.33 |
Molecular Formula: | C13H15NO2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
TG003
Molecular Weight: | 249.33 |
Molecular Formula: | C13H15NO2S |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 17 |
Complexity: | 329 |
Synonyms
TG003
| TG003 | TG003 |
|---|---|
TG003 |
TG-003 |
300801-52-9 |
TG 003 |
(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one |
Cdc2-Like kinase inhibitor |
(1Z)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one |
Cdc2-Like Kinase Inhibitor, TG003 |
719277-26-6 |
CHEMBL408982 |
Clk inhibitor |
1-(3-ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone |
(Z)-1-(3-ethyl-5-methoxybenzodthiazol-2(3H)-ylidene)propan-2-one |
SR-01000076048 |
Clk Inhibitor, TG003 |
MFCD00624584 |
MLS000077198 |
(1Z)-1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone |
GTPL5942 |
SCHEMBL2977826 |
EX-A683 |
HMS2355I17 |
HMS3229E10 |
HMS3262D10 |
ZINC4793192 |
Tox21_500894 |
2753AH |
BDBM50026622 |
s7320 |
STK874212 |
AKOS000546683 |
CCG-204976 |
LP00894 |
SDCCGSBI-0050869.P003 |
NCGC00032387-02 |
NCGC00032387-03 |
NCGC00032387-04 |
NCGC00032387-05 |
NCGC00032387-06 |
NCGC00032387-07 |
NCGC00261579-01 |
BP-20670 |
SMR000001066 |
TG003, >=98% (HPLC) |
EU-0100894 |
SW219950-1 |
K00243 |
A876312 |
J-017766 |
SR-01000076048-1 |
SR-01000076048-2 |
BRD-K97072811-001-07-2 |
BRD-K97072811-001-09-8 |
Q27075810 |
1-3-Ethyl-5-methoxy-3H-benzothiazol-(2Z)-ylidene-propan-2-one |
(1Z)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2(3H)-ylidene)propan-2-one |
(Z)-1-(3-ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene) propan-2-one |
2-Propanone, 1-(3-ethyl-5-methoxy-2(3H)-benzothiazolylidene)-, (1Z)- |
Experimental Data
TG003
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -3.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
TG003
Statistics Data
TG003
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3.000000000000000 | 1 | 1 |
Statistics Data Visualization
TG003
