Compound Summary
TETRACYCLINE HYDROCHLORIDE
Compound Information
TETRACYCLINE HYDROCHLORIDE
Compound Name: | TETRACYCLINE HYDROCHLORIDE |
Compound CID: | 54704426 |
Synonyms: | TETRACYCLINE HYDROCHLORIDE 64-75-5 Tetracycline HCl Achromycin hydrochloride Tetracycline (hydrochloride) More... |
Iupac Name: | (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride |
InChI: | InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1 |
InChIKey: | YCIHPQHVWDULOY-FMZCEJRJSA-N |
Canonical Smiles: | CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl |
Isomeric Smiles: | C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl |
Molecular Weight: | 480.9 |
Molecular Formula: | C22H25ClN2O8 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
TETRACYCLINE HYDROCHLORIDE
Molecular Weight: | 480.9 |
Molecular Formula: | C22H25ClN2O8 |
Hydrogen Bond Donor Count: | 7 |
Hydrogen Bond Acceptor Count: | 9 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 33 |
Complexity: | 971 |
Synonyms
TETRACYCLINE HYDROCHLORIDE
| TETRACYCLINE HYDROCHLORIDE | TETRACYCLINE HYDROCHLORIDE |
|---|---|
TETRACYCLINE HYDROCHLORIDE |
64-75-5 |
Tetracycline HCl |
Achromycin hydrochloride |
Tetracycline (hydrochloride) |
Supramycin |
Sustamycin |
Sumycin |
Telotrex |
UNII-P6R62377KV |
NCI-C55561 |
MFCD00078142 |
Achromycin |
Quatrex |
P6R62377KV |
Bristacycline |
Dumocyclin |
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride |
64-75-5 (HCl) |
Tetracyclinehydrochloride |
DSSTox_CID_1321 |
DSSTox_RID_76081 |
DSSTox_GSID_21321 |
Hostacycline |
Mephacyclin |
Quadracycline |
Remicyclin |
Stilciclina |
Tetrabakat |
Tetracompren |
Tetralution |
Tetramavan |
Topicycline |
Triphacyclin |
Actisite |
Artomycin |
Diacycine |
Partrex |
Piracaps |
Ricycline |
Subamycin |
Tefilin |
Tetrabid |
Tetrablet |
Tetracaps |
Tetrakap |
Tetramed |
Tetrosol |
Paltet |
Qidtet |
Retet |
Teline |
Unicin |
Tetra-wedel |
Neocyclin B |
Ro-Cycline |
Tetracycline.HCl |
Polyotic ointment |
TetraSURE |
Tet-cy |
Tetra-D |
Vetquamycin-324 |
Cancycline-250 |
(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride |
(4S,6S,12aS,4aS,5aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,1 1-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide, chloride |
Cefracycline tablets |
Tetracycline chloride |
Panmycin hydrochloride |
Sentry av ornacycline |
T-250 Capsules |
Tetracyn hydrochloride |
Tetraciclina cloridrato |
ALA TET |
Polycycline hydrochloride |
Chlorowodorku tetracykliny |
Chlorhydrate de tetracycline |
CCRIS 2351 |
SR-01000000212 |
SR-05000001723 |
(-)-Tetrahcycline hydrochloride |
Tetraciclina cloridrato Italian |
Chlorowodorku tetracykliny Polish |
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride |
Prestwick_434 |
EINECS 200-593-8 |
Bristacycline (TN) |
Chlorhydrate de tetracycline French |
Tetracycline hydrochloride USP:JAN |
Tetracycline hydrochloride (internal use) |
AI3-50120 |
CAS-64-75-5 |
NCGC00016291-01 |
EC 200-593-8 |
U-5965 |
SCHEMBL34248 |
SPECTRUM1500566 |
CHEMBL454950 |
DTXSID6021321 |
NCI-c55561;Tetracycline HCl |
Tetracycline hydrochloride, powder |
HMS1568K22 |
HMS1921C19 |
Pharmakon1600-01500566 |
HY-B0474 |
Tox21_110355 |
Tox21_200516 |
CCG-39267 |
NSC757338 |
s2574 |
SBB006497 |
AKOS015951263 |
Tox21_110355_1 |
BCP9000227 |
EBD2198184 |
KS-1431 |
MCULE-8111555447 |
NSC 757338 |
NSC-757338 |
Tetracycline hydrochloride (JP17/USP) |
NCGC00017323-08 |
NCGC00180907-01 |
NCGC00180907-02 |
NCGC00258070-01 |
(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)- |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))- |
K044 |
ST057166 |
BCP0726000161 |
SW196293-4 |
D02122 |
D92606 |
SR-01000000212-4 |
SR-05000001723-2 |
Q27286287 |
Tetracycline hydrochloride 100 microg/mL in Acetonitrile |
Tetracycline hydrochloride, meets USP testing specifications |
Tetracycline hydrochloride, VETRANAL(TM), analytical standard |
Tetracycline hydrochloride, >=95% (European Pharmacopoeia HPLC assay) |
Tetracycline hydrochloride, British Pharmacopoeia (BP) Reference Standard |
Tetracycline hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Tetracycline hydrochloride, powder, BioReagent, suitable for cell culture |
Tetracycline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
Tetracycline hydrochloride, United States Pharmacopeia (USP) Reference Standard |
(4S,4AS,5AS,6S,12AR)-4-(DIMETHYLAMINO)-1,6,10,11,12A-PENTAHYDROXY-6-METHYL-3,12-DIOXO-3,4,4A,5,5A,6,12,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE HYDROCHLORIDE |
(4S,4AS,5aS,6S,12aS)-4-(Dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide hydrochloride |
(4S,4aS,5aS,6S,12aS,Z)-2-(amino(hydroxy)methylene)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5aalpha,6beta,12alpha))- |
2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride,(4S,4aS,5aS,6S,12aS)- |
Experimental Data
TETRACYCLINE HYDROCHLORIDE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 16.370000000000000 | 18.080000000000000 | 10.450000000000000 | S | N2 | 33008901 | Active | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 48.860000000000000 | 46.740000000000000 | -4.341000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 16.000000000000000 | 17.470000000000000 | 9.184000000000000 | S | N2 | 33008901 | Active | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 46.240000000000000 | 48.650000000000000 | 5.228000000000000 | S | FEMALES | 33008901 | Active | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 44.010000000000000 | 44.130000000000000 | 0.279200000000000 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 46.640000000000000 | 46.880000000000000 | 0.506000000000000 | NS | MALES | 33008901 | Inactive |
Experimental Data Visualization
TETRACYCLINE HYDROCHLORIDE
Statistics Data
TETRACYCLINE HYDROCHLORIDE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 10.450000000000000 | 1 | 2 | |
| Drosophila melanogaster | 5.228000000000000 | 1 | 4 |
Statistics Data Visualization
TETRACYCLINE HYDROCHLORIDE
