Compound Summary
TAXIFOLIN
Compound Information
TAXIFOLIN
Compound Name: | TAXIFOLIN |
Compound CID: | 439533 |
Synonyms: | TAXIFOLIN 480-18-2 (+)-Taxifolin dihydroquercetin Distylin More... |
Iupac Name: | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one |
InChI: | InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1 |
InChIKey: | CXQWRCVTCMQVQX-LSDHHAIUSA-N |
Canonical Smiles: | C1=CC(=C(C=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
Isomeric Smiles: | C1=CC(=C(C=C1[C@@H]2[C@H](C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
Molecular Weight: | 304.25 |
Molecular Formula: | C15H12O7 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
TAXIFOLIN
Molecular Weight: | 304.25 |
Molecular Formula: | C15H12O7 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 22 |
Complexity: | 428 |
Synonyms
TAXIFOLIN
| TAXIFOLIN | TAXIFOLIN |
|---|---|
TAXIFOLIN |
480-18-2 |
(+)-Taxifolin |
dihydroquercetin |
Distylin |
Taxifoliol |
(2R,3R)-Dihydroquercetin |
(+)-Dihydroquercetin |
24198-97-8 |
TAXIFOLIN-(+) |
Lariksin |
Lavitol |
(+/-)-Taxifolin |
taxifolin (dihydroquercetin) |
UNII-9SOB9E3987 |
(2R,3R)-3,3,4,5,7-Pentahydroxyflavanone |
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- |
(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one |
(2R,3R)-Taxifolin |
(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one |
(2R,3R)-2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE |
(+/-)-Taxifolin hydrate |
3,5,7,3,4-Pentahydroxyflavanone |
2,3-Dihydroquercetin |
(2R-trans)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4-benzopyrone |
(2R,3R)-(+)-Taxifolin |
17654-26-1 |
CHEBI:17948 |
(+)-(2R,3R)-dihydroquercetin |
9SOB9E3987 |
MFCD00006845 |
Flavanone, 3,3,4,5,7-pentahydroxy- |
Diquertin |
(?)-Taxifolin |
3,3,4,5,7-Pentahydroxyflavanone |
Flamena D |
(2R,3R)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
DQH |
SMR000466389 |
trans-Dihydroquercetin |
(+)-trans-Taxifolin |
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy- |
Dihydroquercetin hydrate |
CCRIS 9292 |
Taxifolin (Tax) |
EINECS 207-543-4 |
(+)-trans Taxifolin |
(2R,3R)-TRANS-DIHYDROQUERCETIN |
BRN 0093548 |
Taxifolin, (+/-)- |
Dihydroquercetin, (+/-)- |
SCHEMBL39786 |
5-18-05-00451 (Beilstein Handbook Reference) |
MLS000759539 |
MLS001066341 |
MLS001074712 |
MLS001424044 |
MLS002153142 |
BIDD:ER0483 |
Taxifolin, analytical standard |
Flavone, 2,3-dihydro-3,3,4,5,7-pentahydroxy- |
MEGxp0_000741 |
DTXSID8022450 |
ACon1_000239 |
BDBM212435 |
DTXSID301017215 |
HMS2051M22 |
HMS2234L14 |
HY-N0136 |
(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-4-one |
AC-935 |
MFCD11044454 |
s2366 |
AKOS015965399 |
ZINC100018343 |
CCG-100909 |
CS-3365 |
DB02224 |
KS-1312 |
MCULE-2394173874 |
MCULE-2692728789 |
NC00159 |
NCGC00016024-08 |
NCGC00180750-01 |
20254-28-8 |
AS-17723 |
(+)-3,3,4,5,7-Pentahydroxyflavanone" |
3,3,4,5,7-Pentahydroxyflavanone hydrate |
SW197539-2 |
V1551 |
C01617 |
(2R,3R)-3,5,7,3,4-Pentahydroxyflavanone |
Q412191 |
SR-01000759385 |
Flavanone, 3,3,4,5,7-pentahydroxy-, (R,R)- |
J-011205 |
SR-01000759385-6 |
Taxifolin, primary pharmaceutical reference standard |
F40AB773-26FA-4112-A46D-DC970AF64BC1 |
Flavanone, 3,3,4,5,7-pentahydroxy-, (2R)-trans-" |
Flavanone, 3,3,4,5,7-pentahydroxy-, trans-(+)-" |
Flavanone, 3,3,4,5,7-pentahydroxy-, (2R,3R)-(+)- |
UNII-EAS93SC1VS component CXQWRCVTCMQVQX-LSDHHAIUSA-N |
rel-(2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one |
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one, (2R-trans)- |
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R-trans)- |
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, trans-(+/-)- |
Experimental Data
TAXIFOLIN
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 164.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 205.000000000000000 | umol/L | 11.260000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 820.000000000000000 | umol/L | 9.020000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 150.000000000000000 | umol/L | 12.020000000000000 | Unclear | N2 | 33683565 | |||||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 657.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 820.000000000000000 | umol/L | 12.000000000000000 | 17.000000000000000 | 0.420000000000000 | S | N2 | 18755260 | Active | ||||
| Caenorhabditis elegans | 205.000000000000000 | umol/L | 10.000000000000000 | 13.000000000000000 | 0.300000000000000 | NS | N2 | 18755260 | Inactive | ||||
| Caenorhabditis elegans | 820.000000000000000 | umol/L | 10.000000000000000 | 20.000000000000000 | 1.000000000000000 | S | N2 | 18755260 | Active | ||||
| Caenorhabditis elegans | 820.000000000000000 | umol/L | 14.000000000000000 | 21.000000000000000 | 0.500000000000000 | S | N2 | 18755260 | Active | ||||
| Caenorhabditis elegans | 150.000000000000000 | umol/L | 14.000000000000000 | 15.000000000000000 | 0.070000000000000 | NS | N2 | 18755260 | Inactive |
Experimental Data Visualization
TAXIFOLIN
Statistics Data
TAXIFOLIN
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 1.000000000000000 | 12.020000000000000 | 2 | 11 |
Statistics Data Visualization
TAXIFOLIN
