Compound Summary
Siguazodan
Compound Information
Siguazodan
Compound Name: | Siguazodan |
Compound CID: | 72124 |
Synonyms: | Siguazodan 115344-47-3 SKF 94836 SK&F 94836 2-Cyano-1-methyl-3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)guanidine More... |
Iupac Name: | 1-cyano-2-methyl-3-[4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]guanidine |
InChI: | InChI=1S/C14H16N6O/c1-9-7-12(21)19-20-13(9)10-3-5-11(6-4-10)18-14(16-2)17-8-15/h3-6,9H,7H2,1-2H3,(H,19,21)(H2,16,17,18) |
InChIKey: | NUHPODZZKHQQET-UHFFFAOYSA-N |
Canonical Smiles: | CC1CC(=O)NN=C1C2=CC=C(C=C2)NC(=NC)NC#N |
Isomeric Smiles: | CC1CC(=O)NN=C1C2=CC=C(C=C2)NC(=NC)NC#N |
Molecular Weight: | 284.32 |
Molecular Formula: | C14H16N6O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Siguazodan
Molecular Weight: | 284.32 |
Molecular Formula: | C14H16N6O |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 21 |
Complexity: | 495 |
Synonyms
Siguazodan
| Siguazodan | Siguazodan |
|---|---|
Siguazodan |
115344-47-3 |
SKF 94836 |
SK&F 94836 |
2-Cyano-1-methyl-3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)guanidine |
NCGC00015947-02 |
1-cyano-2-methyl-3-4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenylguanidine |
DSSTox_CID_25202 |
DSSTox_RID_80746 |
DSSTox_GSID_45202 |
N-Cyano-N-methyl-N-4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenylguanidine" |
Guanidine, N-cyano-N-methyl-N-4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl- |
CAS-115344-47-3 |
Siguazodan INN:BAN |
SR-01000075284 |
SKF-94836 |
SkF94836 |
ACMC-20bv5x |
Lopac0_000997 |
BSPBio_001354 |
KBioGR_000074 |
KBioSS_000074 |
SCHEMBL149133 |
CHEMBL1256712 |
DTXSID0045202 |
SCHEMBL12648714 |
SCHEMBL18522869 |
CHEBI:91791 |
KBio2_000074 |
KBio2_002642 |
KBio2_005210 |
KBio3_000147 |
KBio3_000148 |
Bio2_000074 |
Bio2_000554 |
HMS1361D16 |
HMS1791D16 |
HMS1989D16 |
HMS2090J18 |
HMS3267B05 |
HMS3402D16 |
HMS3412M15 |
HMS3676M15 |
Tox21_110264 |
AKOS024456417 |
Tox21_110264_1 |
CCG-205077 |
IDI1_033824 |
SMP2_000276 |
NCGC00015947-03 |
NCGC00015947-04 |
NCGC00015947-05 |
NCGC00015947-06 |
NCGC00015947-07 |
NCGC00015947-08 |
NCGC00025032-02 |
NCGC00025032-03 |
NCGC00025032-04 |
NCGC00025032-05 |
NCGC00025032-06 |
Guanidine,N-cyano-N-methyl-N-4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl- |
HY-19026 |
DB-041259 |
CS-0014736 |
EU-0100997 |
FT-0631077 |
S 3317 |
AB01275530-01 |
J-003284 |
SR-01000075284-1 |
SR-01000075284-3 |
BRD-A62071884-001-03-8 |
BRD-A91992993-001-01-2 |
Q15633560 |
6-4-(N3 -Methyl-N2 -cyanoguanidino)phenyl-5-methyl-4,5-dihydro-3(2H)-pyridazinone |
N-Cyano-N-methyl-N-4-(1,4,5,6-tetrahydro-4-methyl-6-oxopyridazin)-3alpha-ylphenylguanidine" |
Experimental Data
Siguazodan
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -1.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Siguazodan
Statistics Data
Siguazodan
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -1.000000000000000 | 1 | 1 |
Statistics Data Visualization
Siguazodan
