Compound Summary
Sertraline hydrochloride
Compound Information
Sertraline hydrochloride
Compound Name: | Sertraline hydrochloride |
Compound CID: | 63009 |
Synonyms: | Sertraline hydrochloride 79559-97-0 Sertraline HCl Zoloft Gladem More... |
Iupac Name: | (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride |
InChI: | InChI=1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17-;/m0./s1 |
InChIKey: | BLFQGGGGFNSJKA-XHXSRVRCSA-N |
Canonical Smiles: | CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl |
Isomeric Smiles: | CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl |
Molecular Weight: | 342.7 |
Molecular Formula: | C17H18Cl3N |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Sertraline hydrochloride
Molecular Weight: | 342.7 |
Molecular Formula: | C17H18Cl3N |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 1 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 21 |
Complexity: | 322 |
Synonyms
Sertraline hydrochloride
| Sertraline hydrochloride | Sertraline hydrochloride |
|---|---|
Sertraline hydrochloride |
79559-97-0 |
Sertraline HCl |
Zoloft |
Gladem |
Serad |
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride |
Lustral |
Sertraline (hydrochloride) |
UNII-UTI8907Y6X |
(+)-sertraline hydrochloride |
CHEBI:9124 |
UTI8907Y6X |
rac-cis-Sertraline Hydrochloride |
C17H18Cl3N |
Cp 51,974-1 |
MFCD00895772 |
(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride |
79617-95-1 |
Atruline |
Tresleen |
Cp-51,974-1 |
Tatig |
CP-51974-1 |
DSSTox_CID_20243 |
DSSTox_RID_79456 |
DSSTox_GSID_40243 |
Adjuvin |
Aremis |
MLS001401398 |
(+)-cis-(1S,4S)-1-methylamino-4-(3,4-dichlorophenyl)tetralin hydrochloride |
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-aminium chloride |
(1S-cis)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride |
CAS-79559-97-0 |
NCGC00092386-03 |
SMR000466298 |
C17H17Cl2N.HCl |
Serlift |
Sertraline.HCl |
Sertraline, HCl |
Sertraline hydrochloride USAN:USP |
Zoloft (TN) |
(1S,4S)-1-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-4-(methylamino)naphthalene Hydrochloride |
CPD000466298 |
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride |
Sertraline Impurity G HCl |
(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthylamine hydrochloride |
CHEMBL1709 |
SCHEMBL23230 |
MLS000758929 |
ARONIS24360 |
SPECTRUM1505262 |
SERTRALINE HYDRECHLORIDE |
Methyl2-(Hydroxymethyl)Acrylate |
Sertraline hydrochloride- Bio-X |
DTXSID1040243 |
(+/-)-Sertraline Hydrochloride |
HY-B0176A |
(1R,4S)-SERTRALINE HCL |
AOB2376 |
Cis-N-Methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenaminehydrochloride |
CP-51974-1 HCl |
HMS1922P09 |
Pharmakon1600-01505262 |
Sertraline hydrochloride (JAN/USP) |
Tox21_111199 |
Tox21_500870 |
AC-740 |
CCG-39575 |
CS0024 |
NSC746308 |
NSC758948 |
SBB080777 |
AKOS005267232 |
AKOS015846322 |
Tox21_111199_1 |
CS-2052 |
KS-1111 |
LP00870 |
MCULE-1681469163 |
NC00198 |
NC00726 |
NSC 746308 |
NSC 758948 |
NSC-746308 |
NSC-758948 |
(1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride |
NCGC00092386-01 |
NCGC00092386-13 |
NCGC00261555-01 |
1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, hydrochloride, (1S-cis)- |
BS164399 |
Sertraline hydrochloride Related Compound A |
Sertraline hydrochloride, >=98% (HPLC) |
CP-5197401 |
EU-0100870 |
S4053 |
D00825 |
J10439 |
O12070 |
559S970 |
A839713 |
Q27108281 |
Sertraline hydrochloride 100 microg/mL in Acetonitrile |
Sertraline Hydrochloride 1.0 mg/ml in Methanol (as free base) |
Sertraline hydrochloride, British Pharmacopoeia (BP) Reference Standard |
Sertraline hydrochloride, European Pharmacopoeia (EP) Reference Standard |
(1S,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl(methyl)amine hydrochloride |
(1s,4s)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphthalenaminehydrochloride |
(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine HCl |
(1S,4S)-4-(3,4-dichlorophenyl)(1,2,3,4-tetrahydronaphthyl)methylamine, chlor ide |
Sertraline for peak identification, European Pharmacopoeia (EP) Reference Standard |
Sertraline for system suitability, European Pharmacopoeia (EP) Reference Standard |
Sertraline hydrochloride, United States Pharmacopeia (USP) Reference Standard |
(1 s-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphathalenamine hydrochloride |
(1S,4S)-4-(3,4-Dichlorophenyl)-1,2, 3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride |
(1s-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphathalenamine hydrochloride |
(1S,4S)-4-(3,4-DICHLORO-PHENYL)-1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YL-METHYL-AMINE HYDROCHLORIDE |
1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, hydrochloride, (1S,4S) |
rac-Sertraline Hydrochloride ((1RS,4RS)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Hydrochloride) |
Sertraline hydrochloride racemic mixture, United States Pharmacopeia (USP) Reference Standard |
Sertraline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material |
Experimental Data
Sertraline hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -32.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Sertraline hydrochloride
Statistics Data
Sertraline hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -32.000000000000000 | 1 | 1 |
Statistics Data Visualization
Sertraline hydrochloride
