Compound Summary
Sch 28080
Compound Information
Sch 28080
Compound Name: | Sch 28080 |
Compound CID: | 108137 |
Synonyms: | Sch 28080 Sch-28080 76081-98-6 2-methyl-8-(phenylmethoxy)imidazo1,2-apyridine-3-acetonitrile SCH28080 More... |
Iupac Name: | 2-(2-methyl-8-phenylmethoxyimidazo[1,2-a]pyridin-3-yl)acetonitrile |
InChI: | InChI=1S/C17H15N3O/c1-13-15(9-10-18)20-11-5-8-16(17(20)19-13)21-12-14-6-3-2-4-7-14/h2-8,11H,9,12H2,1H3 |
InChIKey: | PYKJFEPAUKAXNN-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C(N2C=CC=C(C2=N1)OCC3=CC=CC=C3)CC#N |
Isomeric Smiles: | CC1=C(N2C=CC=C(C2=N1)OCC3=CC=CC=C3)CC#N |
Molecular Weight: | 277.32 |
Molecular Formula: | C17H15N3O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Sch 28080
Molecular Weight: | 277.32 |
Molecular Formula: | C17H15N3O |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 21 |
Complexity: | 385 |
Synonyms
Sch 28080
| Sch 28080 | Sch 28080 |
|---|---|
Sch 28080 |
Sch-28080 |
76081-98-6 |
2-methyl-8-(phenylmethoxy)imidazo1,2-apyridine-3-acetonitrile |
SCH28080 |
UNII-00427X161I |
2-(8-(benzyloxy)-2-methylimidazo1,2-apyridin-3-yl)acetonitrile |
Imidazo(1,2-a)pyridine-3-acetonitrile, 2-methyl-8-(phenylmethoxy)- |
CHEMBL47529 |
00427X161I |
Schering compound 28080 |
C17H15N3O |
SR-01000076230 |
S28080 |
2-8-(benzyloxy)-2-methylimidazo1,2-apyridin-3-ylacetonitrile |
2-Methyl-8-(phenylmethoxy)imidazo-(1-2-a)pyrine-3-acetonitrile |
Tocris-1690 |
Lopac-S-4443 |
SCHEMBL1815961 |
ZINC2675 |
CHEBI:92978 |
DTXSID10226971 |
HMS3261G20 |
HMS3268O05 |
HMS3414M11 |
HMS3678M11 |
BDA08198 |
Tox21_500439 |
2-(2-methyl-8-phenylmethoxyimidazo1,2-apyridin-3-yl)acetonitrile |
BDBM50008977 |
MFCD00834620 |
AKOS024456748 |
CCG-204531 |
LP00439 |
SDCCGSBI-0050424.P002 |
VP14349 |
NCGC00015953-01 |
NCGC00015953-02 |
NCGC00015953-03 |
NCGC00015953-04 |
NCGC00015953-05 |
NCGC00015953-08 |
NCGC00025259-01 |
NCGC00025259-02 |
NCGC00025259-03 |
NCGC00261124-01 |
DB-056022 |
HY-103261 |
B6832 |
CS-0026715 |
EU-0100439 |
FT-0641585 |
SCH-28080, >=98% (HPLC), solid |
S 4443 |
SR-01000076230-1 |
SR-01000076230-3 |
BRD-K55748775-001-01-4 |
Q27164711 |
Z2738349261 |
8-benzyloxy-3-cyanomethyl-2-methyl-imidazo1,2-apyridine |
8-Benzyloxy-3-cyanomethyl-2-methylimidazo1,2-apyridine |
(8-Benzyloxy-2-methyl-imidazo1,2-apyridin-3-yl)-acetonitrie |
(8-Benzyloxy-2-methylimidazo1,2-apyridin-3-yl)acetonitrile |
2-Methyl-8-(phenylmethoxy)imidazo1,2-apyridine-3acetonitrile |
(8-Benzyloxy-2-methyl-imidazo1,2-apyridin-3-yl)-acetonitrile |
2-methyl-8 (phenyl-methoxy) imidazo (1,2-a)-pyridine-3-acetonitrile |
Experimental Data
Sch 28080
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -16.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Sch 28080
Statistics Data
Sch 28080
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -16.000000000000000 | 1 | 1 |
Statistics Data Visualization
Sch 28080
