Compound Summary
Salsalate
Compound Information
Salsalate
Compound Name: | Salsalate |
Compound CID: | 5161 |
Synonyms: | Salsalate sasapyrine 552-94-3 Salicylsalicylic acid Disalicylic acid More... |
Iupac Name: | 2-(2-hydroxybenzoyl)oxybenzoic acid |
InChI: | InChI=1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17) |
InChIKey: | WVYADZUPLLSGPU-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C(C(=C1)C(=O)OC2=CC=CC=C2C(=O)O)O |
Isomeric Smiles: | C1=CC=C(C(=C1)C(=O)OC2=CC=CC=C2C(=O)O)O |
Molecular Weight: | 258.23 |
Molecular Formula: | C14H10O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Salsalate
Molecular Weight: | 258.23 |
Molecular Formula: | C14H10O5 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 19 |
Complexity: | 341 |
Synonyms
Salsalate
| Salsalate | Salsalate |
|---|---|
Salsalate |
sasapyrine |
552-94-3 |
Salicylsalicylic acid |
Disalicylic acid |
Disalcid |
2-Carboxyphenyl salicylate |
Sasapyrinum |
Saloxium |
Salicyloylsalicylic acid |
Diacesal |
Diplosal |
Sasapirin |
Sasapyrin |
Disalyl |
Nobacid |
Salical |
Salina |
Salysal |
o-Salicylsalicylic acid |
Sal Ester Sal |
2-(2-hydroxybenzoyl)oxybenzoic acid |
Disalicylsaeure |
Salicylic acid, salicylate |
Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester |
Salsalato |
Salsalatum |
Salflex |
Salsalatum INN-Latin |
NSC-49171 |
Salicylic acid, bimolecular ester |
Salicyloxysalicylic acid |
O-Salicylcylsalicylsaeure |
2-((2-Hydroxybenzoyl)oxy)benzoic acid |
UNII-V9MO595C9I |
2-Hydroxybenzoic acid 2-carboxyphenyl ester |
MFCD00020252 |
Salicylsalicylic acid;Disalicylic acid |
CHEBI:9014 |
V9MO595C9I |
Salicylic acid bimolecular ester |
NSC49171 |
NCGC00096014-01 |
DSSTox_CID_3572 |
DSSTox_RID_77088 |
DSSTox_GSID_23572 |
Salsalato INN-Spanish |
Mono-gesic |
O-Salicyloylsalicylic Acid |
Disalicylic acid; |
Disalcid (TN) |
CAS-552-94-3 |
Sasapyrine (JAN) |
2-(2-hydroxyphenylcarbonyloxy)benzoic acid |
Salsalate (USP/INN) |
EINECS 209-027-4 |
NSC 49171 |
2-Salicyloyloxybenzoic Acid |
BRN 2590908 |
Disalgesic |
Salicylsalicylic Acid (2-(2-Hydroxybenzoyl)oxybenzoic Acid) |
Salsalate USAN:USP:INN:BAN |
Aspirin Impurity E |
2-(2-hydroxybenzoyloxy)benzoic acid |
Spectrum_001998 |
2-Salicylsalicylic acid |
Spectrum2_000693 |
Spectrum3_000173 |
Spectrum4_000940 |
Spectrum5_000670 |
ACMC-209lm5 |
2-{(2-hydroxyphenyl)carbonyloxy}benzoic acid |
2-salicyloyloxy-benzoic acid |
SCHEMBL15562 |
BSPBio_001665 |
KBioGR_001500 |
KBioSS_002572 |
SPECTRUM200331 |
SPBio_000845 |
Acetylsalicylic Acid Impurity E |
CHEMBL154111 |
ZINC2062 |
DTXSID1023572 |
Salsalate, >=98% (HPLC) |
BDBM85244 |
KBio2_002563 |
KBio2_005131 |
KBio2_007699 |
KBio3_001165 |
HMS2091A05 |
HMS3652P07 |
HMS3885J09 |
Pharmakon1600-00200331 |
HY-B1245 |
NSC_5161 |
Benzoic acid, 2-carboxyphenyl ester |
Tox21_111548 |
CCG-39652 |
NSC755823 |
s4188 |
Salicylic Acid 2-Carboxyphenyl Ester |
SBB003097 |
AKOS003368478 |
Tox21_111548_1 |
2-Carboxyphenyl salicylate, AldrichCPR |
CS-4891 |
DB01399 |
MCULE-7200376848 |
NSC-755823 |
NCGC00096014-02 |
NCGC00096014-03 |
AC-18298 |
AS-12645 |
CAS_552-94-3 |
ST083489 |
2-(2-Hydroxybenzoyl)oxybenzoic acid # |
SBI-0206687.P002 |
DB-020760 |
FT-0632376 |
SW219189-1 |
2-(2-hydroxyphenyl)carbonyloxybenzoic acid |
C75590 |
D00428 |
AB01563259_01 |
AB01563259_02 |
A830578 |
SR-05000001536 |
Q-100630 |
Q1320691 |
SR-05000001536-1 |
2-(2-Hydroxybenzoyl)oxybenzoic Acid (Salicylsalicylic Acid) |
Salsalate, United States Pharmacopeia (USP) Reference Standard |
Aspirin Impurity E; 2-Hydroxybenzoic Acid 2-Carboxyphenyl Ester; Salicylic Acid Salicylate; 2-Hydroxybenzoic Acid 2-Carboxyphenyl Ester |
Salsalate (Aspirin Impurity E), Pharmaceutical Secondary Standard; Certified Reference Material |
Experimental Data
Salsalate
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 15.780000000000000 | 15.050000000000000 | -4.623000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.170000000000000 | 42.170000000000000 | -2.302000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 17.010000000000000 | 15.960000000000000 | -6.171000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 44.630000000000000 | 47.650000000000000 | 6.761000000000000 | S | FEMALES | 33008901 | Active |
Experimental Data Visualization
Salsalate
Statistics Data
Salsalate
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4.623000000000000 | 1 | 2 | |
| Drosophila melanogaster | 6.761000000000000 | 1 | 2 |
Statistics Data Visualization
Salsalate
