Compound Summary
SU 4312
Compound Information
SU 4312
Compound Name: | SU 4312 |
Compound CID: | 6450842 |
Synonyms: | SU 4312 5812-07-7 NSC86429 dmbi SU-4312 More... |
Iupac Name: | (3Z)-3-[[4-(dimethylamino)phenyl]methylidene]-1H-indol-2-one |
InChI: | InChI=1S/C17H16N2O/c1-19(2)13-9-7-12(8-10-13)11-15-14-5-3-4-6-16(14)18-17(15)20/h3-11H,1-2H3,(H,18,20)/b15-11- |
InChIKey: | UAKWLVYMKBWHMX-PTNGSMBKSA-N |
Canonical Smiles: | CN(C)C1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O |
Isomeric Smiles: | CN(C)C1=CC=C(C=C1)/C=C\2/C3=CC=CC=C3NC2=O |
Molecular Weight: | 264.32 |
Molecular Formula: | C17H16N2O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
SU 4312
Molecular Weight: | 264.32 |
Molecular Formula: | C17H16N2O |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 20 |
Complexity: | 394 |
Synonyms
SU 4312
| SU 4312 | SU 4312 |
|---|---|
SU 4312 |
5812-07-7 |
NSC86429 |
dmbi |
SU-4312 |
SU4312 |
CHEMBL328710 |
3-(4-(Dimethylamino)benzylidene)-1,3-dihydro-2H-indol-2-one |
(3Z)-3-4-(dimethylamino)phenylmethylidene-1H-indol-2-one |
3-4-(dimethylamino)phenylmethylene-1,3-dihydro-2H-indol-2-one |
90828-16-3 |
3-4-(dimethylamino)benzylideneindolin-2-one |
NSC 86429 |
SR-01000076222 |
BiomolKI_000054 |
BiomolKI2_000060 |
UPCMLD-DP118 |
cis-SU 4312 |
Lopac0_001121 |
BMK1-F6 |
BSPBio_000998 |
SCHEMBL1982207 |
UPCMLD-DP118:001 |
UPCMLD-DP118:002 |
BDBM17747 |
HMS1362B19 |
HMS1792B19 |
HMS1990B19 |
HMS3263B03 |
HMS3403B19 |
HMS3412D03 |
HMS3676D03 |
BCP20743 |
Tox21_501121 |
NSC-86429 |
STK946565 |
ZINC12339625 |
AKOS005640946 |
(Z)-SU4312 |
CCG-100658 |
LP01121 |
SDCCGSBI-0051089.P002 |
SU4312(NSC86429) |
IDI1_002094 |
NCGC00025170-02 |
NCGC00025170-03 |
NCGC00025170-04 |
NCGC00025170-05 |
NCGC00025170-06 |
NCGC00025170-07 |
NCGC00025170-08 |
NCGC00025170-09 |
NCGC00025170-10 |
NCGC00025170-11 |
NCGC00025170-12 |
NCGC00025170-14 |
NCGC00261806-01 |
B6746 |
EU-0101121 |
EC-000.2453 |
S 8567 |
(Z)-3-(4-(dimethylamino)benzylidene)indolin-2-one |
SR-01000076222-1 |
SR-01000076222-3 |
BRD-K20287671-001-01-0 |
(3Z)-3-(4-dimethylaminophenyl)methyleneindolin-2-one |
DMBI; (Z)-3-(4-(dimethylamino)benzylidene)indolin-2-one |
(3Z)-3-4-(dimethylamino)benzylidene-1,3-dihydro-2H-indol-2-one |
(3Z)-3-{4-(dimethylamino)phenylmethylidene}-2,3-dihydro-1H-indol-2-one |
SU-4312; SU4312. DMBI; NSC 86429; NSC-86429; NSC86429 |
Experimental Data
SU 4312
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 5.000000000000000 | S | N2 | 33683565 | Active | ||||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 16.000000000000000 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 88.000000000000000 | umol/L | 5.000000000000000 | S | N2 | 24134630 | Active |
Experimental Data Visualization
SU 4312
Statistics Data
SU 4312
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 16.000000000000000 | 2 | 3 |
Statistics Data Visualization
SU 4312
