Compound Summary
SKF-83,959
Compound Information
SKF-83,959
Compound Name: | SKF-83,959 |
Compound CID: | 133538 |
Synonyms: | SKF-83,959 Skf-83959 SKF 83959 80751-85-5 SK&F 83959 More... |
Iupac Name: | 9-chloro-3-methyl-5-(3-methylphenyl)-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol |
InChI: | InChI=1S/C18H20ClNO2/c1-11-4-3-5-12(8-11)15-10-20(2)7-6-13-14(15)9-16(21)18(22)17(13)19/h3-5,8-9,15,21-22H,6-7,10H2,1-2H3 |
InChIKey: | JXMYTVOBSFOHAF-UHFFFAOYSA-N |
Canonical Smiles: | CC1=CC(=CC=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)C |
Isomeric Smiles: | CC1=CC(=CC=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)C |
Molecular Weight: | 317.8 |
Molecular Formula: | C18H20ClNO2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
SKF-83,959
Molecular Weight: | 317.8 |
Molecular Formula: | C18H20ClNO2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 22 |
Complexity: | 380 |
Synonyms
SKF-83,959
| SKF-83,959 | SKF-83,959 |
|---|---|
SKF-83,959 |
Skf-83959 |
SKF 83959 |
80751-85-5 |
SK&F 83959 |
SKF83959 |
3-Methyl-6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(3-methylphenyl)-1H-3-benzazepine |
CHEMBL574558 |
CHEBI:64001 |
6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol |
9-chloro-3-methyl-5-(3-methylphenyl)-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol |
CHEMBL520992 |
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol |
Lopac0_001067 |
GTPL8443 |
SCHEMBL2970804 |
DTXSID8043818 |
BDBM50274531 |
CCG-205144 |
SDCCGSBI-0051037.P002 |
5H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)- |
NCGC00015940-03 |
NCGC00015940-04 |
NCGC00015940-08 |
NCGC00025350-02 |
L000850 |
BRD-A04260165-004-02-4 |
Q27088813 |
6-chloro-3-methyl-1-(3-methylphenyl)-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol |
6-chloro-3-methyl-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzodazepine-7,8-diol hydrobromide |
6-Chloro-3-methyl-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzodazepine-7,8-diol; hydrobromide |
Experimental Data
SKF-83,959
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200.000000000000000 | umol/L | 45.820000000000000 | 43.610000000000000 | -4.819000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 49.360000000000000 | 46.820000000000000 | -5.139000000000000 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
SKF-83,959
Statistics Data
SKF-83,959
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | -4.819000000000000 | 1 | 2 |
Statistics Data Visualization
SKF-83,959
