Compound Summary
SB-215505
Compound Information
SB-215505
Compound Name: | SB-215505 |
Compound CID: | 10449757 |
Synonyms: | SB-215505 Sb 215505 162100-15-4 6-Chloro-5-methyl-N-(quinolin-5-yl)indoline-1-carboxamide 6-chloro-5-methyl-1-(5-quinolylcarbamoyl)indoline More... |
Iupac Name: | 6-chloro-5-methyl-N-quinolin-5-yl-2,3-dihydroindole-1-carboxamide |
InChI: | InChI=1S/C19H16ClN3O/c1-12-10-13-7-9-23(18(13)11-15(12)20)19(24)22-17-6-2-5-16-14(17)4-3-8-21-16/h2-6,8,10-11H,7,9H2,1H3,(H,22,24) |
InChIKey: | HOVMHIRTZYQSKM-UHFFFAOYSA-N |
Canonical Smiles: | CC1=CC2=C(C=C1Cl)N(CC2)C(=O)NC3=CC=CC4=C3C=CC=N4 |
Isomeric Smiles: | CC1=CC2=C(C=C1Cl)N(CC2)C(=O)NC3=CC=CC4=C3C=CC=N4 |
Molecular Weight: | 337.8 |
Molecular Formula: | C19H16ClN3O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
SB-215505
Molecular Weight: | 337.8 |
Molecular Formula: | C19H16ClN3O |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 24 |
Complexity: | 474 |
Synonyms
SB-215505
| SB-215505 | SB-215505 |
|---|---|
SB-215505 |
Sb 215505 |
162100-15-4 |
6-Chloro-5-methyl-N-(quinolin-5-yl)indoline-1-carboxamide |
6-chloro-5-methyl-1-(5-quinolylcarbamoyl)indoline |
6-chloro-5-methyl-N-quinolin-5-yl-2,3-dihydroindole-1-carboxamide |
GTPL190 |
SCHEMBL1157493 |
ZINC7442 |
CHEMBL2110371 |
BDBM85859 |
MFCD05664741 |
AKOS025293478 |
SB73117 |
HY-18596 |
CS-0011469 |
6-Chloro-5-methyl-1-5-quinolycarbamoyl-indoline |
L018293 |
Q27088701 |
6-Chloro-2,3-dihydro-5-methyl-N-5-quinolinyl-1H-indole-1-carboxamide |
6-chloro-5-methyl-N-(5-quinolinyl)-2,3-dihydro-1h-indole-1-carboxamide |
Experimental Data
SB-215505
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -6.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
SB-215505
Statistics Data
SB-215505
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6.000000000000000 | 1 | 1 |
Statistics Data Visualization
SB-215505
