Compound Summary
SB 205384
Compound Information
SB 205384
Compound Name: | SB 205384 |
Compound CID: | 197690 |
Synonyms: | SB 205384 160296-13-9 SB-205384 SB205384 but-2-ynyl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-1benzothiolo2,3-bpyridine-3-carboxylate More... |
Iupac Name: | but-2-ynyl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylate |
InChI: | InChI=1S/C17H18N2O3S/c1-3-4-7-22-17(21)13-9(2)19-16-14(15(13)18)11-6-5-10(20)8-12(11)23-16/h10,20H,5-8H2,1-2H3,(H2,18,19) |
InChIKey: | JDTZAGLGBRRCJT-UHFFFAOYSA-N |
Canonical Smiles: | CC#CCOC(=O)C1=C(N=C2C(=C1N)C3=C(S2)CC(CC3)O)C |
Isomeric Smiles: | CC#CCOC(=O)C1=C(N=C2C(=C1N)C3=C(S2)CC(CC3)O)C |
Molecular Weight: | 330.4 |
Molecular Formula: | C17H18N2O3S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
SB 205384
Molecular Weight: | 330.4 |
Molecular Formula: | C17H18N2O3S |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 23 |
Complexity: | 528 |
Synonyms
SB 205384
| SB 205384 | SB 205384 |
|---|---|
SB 205384 |
160296-13-9 |
SB-205384 |
SB205384 |
but-2-ynyl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-1benzothiolo2,3-bpyridine-3-carboxylate |
4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo(b)thieno(2,3-b)pyridine-3-carboxylic acid but-2-ynyl ester |
but-2-ynyl (7R)-4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-1benzothiolo2,3-bpyridine-3-carboxylate |
4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzobthieno2,3-bpyridine-3-carboxylic acid but-2-ynyl ester |
SR-01000076138 |
But-2-ynyl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-(1)benzothiolo(2,3-b)pyridine-3-carboxylate |
SB 205384, solid |
Lopac0_001119 |
MLS002153326 |
CHEMBL1256667 |
SCHEMBL17236317 |
CHEBI:91586 |
DTXSID00936259 |
HMS2232M03 |
HMS3263O20 |
HMS3268A07 |
HMS3370F18 |
HMS3412H03 |
HMS3676H03 |
Tox21_501119 |
AKOS024456640 |
CCG-205195 |
LP01119 |
SDCCGSBI-0051088.P002 |
NCGC00015969-03 |
NCGC00015969-04 |
NCGC00015969-05 |
NCGC00015969-08 |
NCGC00025197-02 |
NCGC00162349-01 |
NCGC00261804-01 |
SMR001230739 |
EU-0101119 |
(+)-SB205384 |
S 7936 |
(+)-SB-205384 |
J-009707 |
Q7388903 |
SR-01000076138-2 |
SR-01000076138-3 |
BRD-A22707317-001-02-5 |
(+)-2-Butyn-1-yl 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl(1)benzothieno(2,3-b)pyridine-3-carboxylate |
(1)Benzothieno(2,3-b)pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butyn-1-yl ester |
(1)Benzothieno(2,3-b)pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butyn-1-yl ester, (+)- |
2-Butyn-1-yl 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl(1)benzothieno(2,3-b)pyridine-3-carboxylate |
207727-26-2 |
4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-1Hbenzothieno2,3-bpyridine-3-carboxylic acid 2-butynyl ester |
But-2-yn-1-yl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro1benzothieno2,3-bpyridine-3-carboxylate |
Experimental Data
SB 205384
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -11.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
SB 205384
Statistics Data
SB 205384
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -11.000000000000000 | 1 | 1 |
Statistics Data Visualization
SB 205384
