Compound Summary
Ro 41-1049 hydrochloride
Compound Information
Ro 41-1049 hydrochloride
Compound Name: | Ro 41-1049 hydrochloride |
Compound CID: | 5311308 |
Synonyms: | Ro 41-1049 hydrochloride RO-41-1049 hydrochloride 127917-66-2 UNII-19Z49HUF4G Ro 41-1049 (hydrochloride) More... |
Iupac Name: | N-(2-aminoethyl)-5-(3-fluorophenyl)-1,3-thiazole-4-carboxamide;hydrochloride |
InChI: | InChI=1S/C12H12FN3OS.ClH/c13-9-3-1-2-8(6-9)11-10(16-7-18-11)12(17)15-5-4-14;/h1-3,6-7H,4-5,14H2,(H,15,17);1H |
InChIKey: | RRNSPXUFTKJIEZ-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=CC(=C1)F)C2=C(N=CS2)C(=O)NCCN.Cl |
Isomeric Smiles: | C1=CC(=CC(=C1)F)C2=C(N=CS2)C(=O)NCCN.Cl |
Molecular Weight: | 301.77 |
Molecular Formula: | C12H13ClFN3OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Ro 41-1049 hydrochloride
Molecular Weight: | 301.77 |
Molecular Formula: | C12H13ClFN3OS |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 19 |
Complexity: | 293 |
Synonyms
Ro 41-1049 hydrochloride
| Ro 41-1049 hydrochloride | Ro 41-1049 hydrochloride |
|---|---|
Ro 41-1049 hydrochloride |
RO-41-1049 hydrochloride |
127917-66-2 |
UNII-19Z49HUF4G |
Ro 41-1049 (hydrochloride) |
Ro 41-1049 |
N-(2-Aminoethyl)-5-(3-fluorophenyl)-4-thiazolecarboxamide hydrochloride |
19Z49HUF4G |
4-Thiazolecarboxamide, N-(2-aminoethyl)-5-(3-fluorophenyl)-, hydrochloride (1:1) |
N-(2-aminoethyl)-5-(3-fluorophenyl)-1,3-thiazole-4-carboxamide;hydrochloride |
MLS000860021 |
SCHEMBL1665880 |
CHEMBL1256290 |
RO41-1049 HCl |
CFA91766 |
EX-A2359 |
CS-5591 |
HY-100027A |
LP01113 |
Ro-411049 |
NCGC00094383-01 |
SMR000326879 |
EU-0101113 |
A921450 |
SR-01000075635 |
J-005497 |
SR-01000075635-2 |
Q27252138 |
N-(2-aminoethyl)-5-(3-fluorophenyl)thiazole-4-carboxamide hydrochloride |
N-(2-aminoethyl)-5-(m-fluorophenyl)-4-thiazole carboxamide hydrochloride |
N-(2-Aminoethyl)-5-(3-fluorophenyl)-1,3-thiazole-4-carboxamide,hydrochloride |
Experimental Data
Ro 41-1049 hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -8.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Ro 41-1049 hydrochloride
Statistics Data
Ro 41-1049 hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -8.000000000000000 | 1 | 1 |
Statistics Data Visualization
Ro 41-1049 hydrochloride
