Compound Summary
Ranolazine dihydrochloride
Compound Information
Ranolazine dihydrochloride
Compound Name: | Ranolazine dihydrochloride |
Compound CID: | 71279 |
Synonyms: | Ranolazine dihydrochloride 95635-56-6 Ranolazine HCl Ranolazine hydrochloride Ranolazine 2HCl More... |
Iupac Name: | N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide;dihydrochloride |
InChI: | InChI=1S/C24H33N3O4.2ClH/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3;;/h4-10,20,28H,11-17H2,1-3H3,(H,25,29);2*1H |
InChIKey: | RJNSNFZXAZXOFX-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O.Cl.Cl |
Isomeric Smiles: | CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O.Cl.Cl |
Molecular Weight: | 500.5 |
Molecular Formula: | C24H35Cl2N3O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Ranolazine dihydrochloride
Molecular Weight: | 500.5 |
Molecular Formula: | C24H35Cl2N3O4 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 9 |
Heavy Atom Count: | 33 |
Complexity: | 531 |
Synonyms
Ranolazine dihydrochloride
| Ranolazine dihydrochloride | Ranolazine dihydrochloride |
|---|---|
Ranolazine dihydrochloride |
95635-56-6 |
Ranolazine HCl |
Ranolazine hydrochloride |
Ranolazine 2HCl |
Ranolazine (dihydrochloride) |
N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide dihydrochloride |
RS-43285 |
RS 43285-193 |
RS 43285 |
Ranolazine hydrochloride USAN |
renolazine |
N-(2,6-dimethylphenyl)-2-4-2-hydroxy-3-(2-methoxyphenoxy)propylpiperazin-1-ylacetamide dihydrochloride |
95635-56-6 (HCl) |
MFCD03788770 |
CVT 303 (dihydrochloride);RS 43285 |
CVT 303;RS 43285-003 |
Ranolazine hydrochloride (USAN) |
N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)-propyl)piperazin-1-yl)acetamide dihydrochloride |
N-(2,6-Dimethylphenyl)-4-2-hydroxy-3-(2-methoxyphenoxy)propyl-1-piperazineacetamide dihydrochloride |
N-(2,6-dimethylphenyl)-2-{4-2-hydroxy-3-(2-methoxyphenoxy)propylpiperazin-1-yl}acetamide dihydrochloride |
Ranolazindihydrochlorid |
ra-nolazine hydrochloride |
(+-)-4-(2-Hydroxy-3-(o-methoxyphenoxy)propyl)-1-piperazineaceto-2,6-xylidide dihydrochloride |
SCHEMBL230758 |
C24H35Cl2N3O4 |
CHEMBL1526084 |
DTXSID50904741 |
ACT06287 |
BCP22680 |
Tox21_501062 |
s1425 |
AKOS015900516 |
AC-3497 |
CCG-222366 |
CS-1130 |
H35R555 |
LP01062 |
NCGC00094343-01 |
NCGC00261747-01 |
1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-, dihydrochloride, (+-)- |
AS-74881 |
HY-17401 |
N-(2,6-dimethylphenyl)-2-4-2-hydroxy-3-(2-methoxyphenoxy)propylpiperazin-1-ylacetamide;dihydrochloride |
R463 |
AB0007810 |
EU-0101062 |
FT-0630989 |
R0112 |
SW197620-3 |
D05701 |
R 6152 |
T73098 |
A845356 |
Ranolazine dihydrochloride, >=98% (HPLC), powder |
SR-01000076216-2 |
Q27277741 |
6-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-HEXANOICACID |
N-(2,6-Dimethylphenyl)-4-2-hydroxy-3-(2-methoxyphenoxy) |
() -4-2-Hydroxy-3-(o-methoxyphenoxy)propyl-1-piperazineaceto-2,6-xylidide dihydrochloride |
1-3-(2-methoxyphenoxy)-2-hydroxypropyl-4-(2,6-dimethylphenyl)aminocarbonylmethylpiperazine 2HCl |
1-3-(2-methoxyphenoxy)-2-hydroxypropyl-4-(2,6-dimethylphenyl)aminocarbonylmethylpiperazine dihydrochloride salt |
propyl-1-piperazineacetamide dihydrochloride; ( inverted question mark) -4-2-hydroxy-3-(o-methoxyphenoxy)propyl-1-piperazineaceto-2,6-xylidide dihydrochloride" |
Experimental Data
Ranolazine dihydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Ranolazine dihydrochloride
Statistics Data
Ranolazine dihydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -7.000000000000000 | 1 | 1 |
Statistics Data Visualization
Ranolazine dihydrochloride
