Compound Summary
Pilocarpine nitrate
Compound Information
Pilocarpine nitrate
Compound Name: | Pilocarpine nitrate |
Compound CID: | 657349 |
Synonyms: | Pilocarpine nitrate 148-72-1 Pilofrin Pilagan Pilocarpine nitrate salt More... |
Iupac Name: | (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one;nitric acid |
InChI: | InChI=1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1 |
InChIKey: | PRZXEPJJHQYOGF-GNAZCLTHSA-N |
Canonical Smiles: | CCC1C(COC1=O)CC2=CN=CN2C.[N+](=O)(O)[O-] |
Isomeric Smiles: | CC[C@H]1[C@H](COC1=O)CC2=CN=CN2C.[N+](=O)(O)[O-] |
Molecular Weight: | 271.27 |
Molecular Formula: | C11H17N3O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Pilocarpine nitrate
Molecular Weight: | 271.27 |
Molecular Formula: | C11H17N3O5 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 19 |
Complexity: | 270 |
Synonyms
Pilocarpine nitrate
| Pilocarpine nitrate | Pilocarpine nitrate |
|---|---|
Pilocarpine nitrate |
148-72-1 |
Pilofrin |
Pilagan |
Pilocarpine nitrate salt |
Pilocarpine (nitrate) |
UNII-M20T465H6J |
Pilocarpine nitrate USP |
2(3H)-Furanone, 3-ethyldihydro-4-(1-methyl-1H-imidazol-5-yl)methyl-, (3S,4R)-, nitrate (1:1) |
MLS000069669 |
M20T465H6J |
MFCD00078497 |
(3S,4R)-3-Ethyl-4-((1-methyl-1H-imidazol-5-yl)methyl)dihydrofuran-2(3H)-one nitrate |
SMR000058498 |
Pilocarpine nitrate (USP) |
(3S,4R)-3-ethyl-4-(3-methylimidazol-4-yl)methyloxolan-2-one;nitric acid |
pilocarpin nitrate |
Pilocarpini nitras |
Pilocarpine mononitrate |
SR-01000075339 |
P. V. carpine liquifilm |
SR-01000000054 |
2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S,4R)-, nitrate (1:1) |
Prestwick_282 |
EINECS 205-723-7 |
Pilagan (TN) |
Pilocarpine, mononitrate |
regid855878 |
Opera_ID_1243 |
SCHEMBL41889 |
SPECTRUM1500487 |
CHEMBL1213136 |
HMS501B20 |
DTXSID80883277 |
HMS1569I20 |
HMS1920H14 |
HMS2091P18 |
HMS2096I20 |
HMS2235P11 |
HMS3262P22 |
HMS3713I20 |
Pharmakon1600-01500487 |
HY-B1006 |
Tox21_500960 |
CCG-38830 |
NSC757282 |
AKOS016009842 |
CS-4503 |
LP00960 |
NSC 757282 |
NSC-757282 |
NCGC00094261-01 |
NCGC00261645-01 |
Q773 |
EU-0100960 |
D05478 |
P 6628 |
T71804 |
Pilocarpine nitrate salt, >=98% (TLC), powder |
SR-01000000054-7 |
SR-01000075339-2 |
SR-01000075339-5 |
Pilocarpine nitrate salt, tested according to Ph.Eur. |
Pilocarpine nitrate, meets USP testing specifications |
Q27283365 |
SR-01000075339-10 |
Pilocarpine nitrate, British Pharmacopoeia (BP) Reference Standard |
Pilocarpine nitrate, European Pharmacopoeia (EP) Reference Standard |
Pilocarpine nitrate, United States Pharmacopeia (USP) Reference Standard |
Pilocarpine nitrate for system suitability, European Pharmacopoeia (EP) Reference Standard |
Pilocarpine Nitrate, Pharmaceutical Secondary Standard; Certified Reference Material |
2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S,4R)-, mononitrate |
2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S-cis)-, mononitrate |
Experimental Data
Pilocarpine nitrate
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -4.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Pilocarpine nitrate
Statistics Data
Pilocarpine nitrate
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4.000000000000000 | 1 | 1 |
Statistics Data Visualization
Pilocarpine nitrate
