Compound Summary
PROPAFENONE HYDROCHLORIDE
Compound Information
PROPAFENONE HYDROCHLORIDE
Compound Name: | PROPAFENONE HYDROCHLORIDE |
Compound CID: | 36708 |
Synonyms: | PROPAFENONE HYDROCHLORIDE 34183-22-7 Propafenone HCl Rythmol Rytmonorm More... |
Iupac Name: | 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one;hydrochloride |
InChI: | InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H |
InChIKey: | XWIHRGFIPXWGEF-UHFFFAOYSA-N |
Canonical Smiles: | CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl |
Isomeric Smiles: | CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl |
Molecular Weight: | 377.9 |
Molecular Formula: | C21H28ClNO3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
PROPAFENONE HYDROCHLORIDE
Molecular Weight: | 377.9 |
Molecular Formula: | C21H28ClNO3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 11 |
Heavy Atom Count: | 26 |
Complexity: | 368 |
Synonyms
PROPAFENONE HYDROCHLORIDE
| PROPAFENONE HYDROCHLORIDE | PROPAFENONE HYDROCHLORIDE |
|---|---|
PROPAFENONE HYDROCHLORIDE |
34183-22-7 |
Propafenone HCl |
Rythmol |
Rytmonorm |
Arythmol |
Pronon |
Rythmol SR |
Propafenone (hydrochloride) |
Propafenon hydrochlorid |
SA-79 (hydrochloride) |
1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride |
1-2-2-hydroxy-3-(propylamino)propoxyphenyl-3-phenylpropan-1-one hydrochloride |
1-{2-2-hydroxy-3-(propylamino)propoxyphenyl}-3-phenylpropan-1-one hydrochloride |
C21H28ClNO3 |
1-2-2-hydroxy-3-(propylamino)propoxyphenyl-3-phenylpropan-1-one;hydrochloride |
MLS000069682 |
CHEBI:8466 |
Baxarytmon |
Fenoprain |
MFCD00079243 |
Rhythmonorm |
SMR000058493 |
1-2-2-hydroxy-3-(propylamino)propoxyphenyl-3-phenyl-1-propanone hydrochloride |
1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, hydrochloride |
SA 79 |
1-2-(2-Hydroxy-3-(propylamino)propoxy)phenyl-3-phenyl-1-propanone hydrochloride |
Propafenon hydrochlorid German |
SR-01000000192 |
EINECS 251-867-9 |
WZ 884 |
Propafenone, HCl |
Prestwick_831 |
Rythmol (TN) |
ACMC-20cvw7 |
ACMC-20cvw9 |
Propafenone hydrochloride USAN:USP:JAN |
Opera_ID_1835 |
2-(2-Hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenone hydrochloride |
SCHEMBL41412 |
MLS001148185 |
MLS002222267 |
SPECTRUM1503935 |
CHEMBL1201063 |
HY-B0432A |
DTXSID101017233 |
HMS1569D19 |
HMS1922M16 |
Pharmakon1600-01503935 |
BCP28548 |
Tox21_500919 |
CCG-39061 |
NSC758640 |
AKOS008901409 |
Propafenone hydrochloride (JP17/USP) |
KS-5030 |
LP00919 |
MCULE-5193630487 |
NSC 758640 |
NSC-758640 |
Propiophenone, 2-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-, hydrochloride |
NCGC00094230-01 |
NCGC00094230-02 |
NCGC00094230-03 |
NCGC00094230-04 |
NCGC00094230-05 |
NCGC00261604-01 |
AC-11360 |
AC-33196 |
AB0011670 |
DB-048579 |
EU-0100919 |
FT-0630579 |
P2301 |
EN300-51034 |
D00640 |
J10361 |
P 4670 |
183P227 |
A822113 |
J-019481 |
SR-01000000192-2 |
SR-01000000192-6 |
Q27108087 |
Z802671518 |
1-(2-2-Hydroxy-3-(propylamino)propoxyphenyl)-3-phenyl-1propanone |
2-(2-hydroxy-3-propylaminopropoxy)-3-phenylpropiophenone hydrochloride |
Propafenone hydrochloride, European Pharmacopoeia (EP) Reference Standard |
1-2-2-oxidanyl-3-(propylamino)propoxyphenyl-3-phenyl-propan-1-one hydrochloride |
2-hydroxy-3-2-(3-phenylpropanoyl)phenoxy-N-propylpropan-1-aminium chloride |
hydron;1-2-2-hydroxy-3-(propylamino)propoxyphenyl-3-phenylpropan-1-one;chloride |
Propafenone hydrochloride, United States Pharmacopeia (USP) Reference Standard |
1-Propanone,1-2-(2R)-2-hydroxy-3-(propylamino)propoxyphenyl-3-phenyl-, hydrochloride(9CI) |
1-Propanone,1-2-(2S)-2-hydroxy-3-(propylamino)propoxyphenyl-3-phenyl-, hydrochloride(1:1) |
Experimental Data
PROPAFENONE HYDROCHLORIDE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
PROPAFENONE HYDROCHLORIDE
Statistics Data
PROPAFENONE HYDROCHLORIDE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -7.000000000000000 | 1 | 1 |
Statistics Data Visualization
PROPAFENONE HYDROCHLORIDE
