Compound Summary
PROMAZINE HYDROCHLORIDE
Compound Information
PROMAZINE HYDROCHLORIDE
Compound Name: | PROMAZINE HYDROCHLORIDE |
Compound CID: | 5887 |
Synonyms: | PROMAZINE HYDROCHLORIDE 53-60-1 Promazine Hcl Sparine Starazin More... |
Iupac Name: | N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride |
InChI: | InChI=1S/C17H20N2S.ClH/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19;/h3-6,8-11H,7,12-13H2,1-2H3;1H |
InChIKey: | JIVSXRLRGOICGA-UHFFFAOYSA-N |
Canonical Smiles: | CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl |
Isomeric Smiles: | CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl |
Molecular Weight: | 320.9 |
Molecular Formula: | C17H21ClN2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
PROMAZINE HYDROCHLORIDE
Molecular Weight: | 320.9 |
Molecular Formula: | C17H21ClN2S |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 21 |
Complexity: | 285 |
Synonyms
PROMAZINE HYDROCHLORIDE
| PROMAZINE HYDROCHLORIDE | PROMAZINE HYDROCHLORIDE |
|---|---|
PROMAZINE HYDROCHLORIDE |
53-60-1 |
Promazine Hcl |
Sparine |
Starazin |
Talofen |
Promazine (hydrochloride) |
Promazine monohydrochloride |
UNII-U16EOR79U4 |
RP 4560 |
N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine hydrochloride |
Promazine hydrochloride USP |
MLS000069671 |
U16EOR79U4 |
N-(3-(Dimethylamino)propyl)phenothiazine hydrochloride |
10-(3-(Dimethylamino)propyl)phenothiazine hydrochloride |
SMR000058499 |
DSSTox_CID_26949 |
DSSTox_RID_82026 |
DSSTox_GSID_46949 |
10-(3-(Dimethylamino)propyl)phenothiazine monohydrochloride |
10-(gamma-Dimethylamino-n-propyl)phenothiazine hydrochloride |
Promazine hydrochloride (USP) |
10H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride |
10H-Phenothiazine-10-propanamine, N,N-dimethyl-, hydrochloride (1:1) |
CHEBI:8460 |
N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydrochloride |
Chlorowodorek promazyny |
Chlorowodorek promazyny Polish |
CAS-53-60-1 |
SR-01000000228 |
NCGC00015829-02 |
EINECS 200-179-7 |
NSC 17468 |
N-3-(Dimethylamino)propylphenothiazine hydrochloride |
10-(3-Dimethylaminopropyl)phenothiazine hydrochloride |
10-3-(Dimethylamino)propylphenothiazine hydrochloride |
Esparinal |
Verofen |
AI3-28022 |
SR-01000000228-4 |
Promazine chloride |
Promazine-d6 HCl |
Prestwick_974 |
Sparine (TN) |
Romtiazin hydrochloride |
Opera_ID_41 |
Sinophenin hydrochloride |
Phenothiazine, 10-(3-(dimethylamino)propyl)-, hydrochloride |
Propazin (pharmaceutical) |
PROMAZINEHYDROCHLORIDE |
REGID_for_CID_5887 |
MLS001148436 |
MLS002222285 |
SCHEMBL123418 |
SPECTRUM1500509 |
CHEMBL1200469 |
DTXSID4046949 |
HMS1570K07 |
HMS1920L14 |
Pharmakon1600-01500509 |
HY-B1225 |
NSC17468 |
Phenothiazine, 10-(3-(dimethylamino)propyl)-, monohydrochloride |
Tox21_110235 |
Tox21_500961 |
10-H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride |
CCG-40284 |
MFCD00058535 |
NSC-17468 |
NSC757300 |
s5428 |
AKOS015964305 |
Tox21_110235_1 |
CS-4873 |
KS-1384 |
LP00961 |
NSC-757300 |
NCGC00015829-12 |
NCGC00094262-01 |
NCGC00094262-02 |
NCGC00094262-03 |
NCGC00094262-04 |
NCGC00094262-05 |
NCGC00261646-01 |
AC-18101 |
U457 |
EU-0100961 |
FT-0674047 |
WLN: T C666 BN ISJ B3N1&1 &GH |
D00797 |
D78322 |
P 6656 |
SR-01000000228-2 |
SR-01000000228-8 |
W-105721 |
10-(3-Dimethylaminopropyl)phenothiazine hydrochloride |
Q27108085 |
Z2784093694 |
Promazine hydrochloride, VETRANAL(TM), analytical standard |
10-(.gamma.-Dimethylamino-n-propyl)phenothiazine hydrochloride |
dimethyl3-(10H-phenothiazin-10-yl)propylamine hydrochloride |
Promazine Hydrochloride 1.0 mg/ml in Methanol (as free base) |
N,N-Dimethyl-3-(10H-phenothiazin-10-yl)-1-propanamine hydrochloride |
Promazine hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Promazine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
Experimental Data
PROMAZINE HYDROCHLORIDE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20.000000000000000 | umol/L | 49.360000000000000 | 46.740000000000000 | -5.293000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 45.820000000000000 | 45.370000000000000 | -0.972300000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -14.000000000000000 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 16.580000000000000 | 17.000000000000000 | 2.555000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 17.280000000000000 | 17.100000000000000 | -1.029000000000000 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
PROMAZINE HYDROCHLORIDE
Statistics Data
PROMAZINE HYDROCHLORIDE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2.555000000000000 | 2 | 3 | |
| Drosophila melanogaster | -0.972300000000000 | 1 | 2 |
Statistics Data Visualization
PROMAZINE HYDROCHLORIDE
