Compound Summary
PQ401
Compound Information
PQ401
Compound Name: | PQ401 |
Compound CID: | 9549305 |
Synonyms: | PQ401 196868-63-0 PQ 401 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea PQ-401 More... |
Iupac Name: | 1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea |
InChI: | InChI=1S/C18H16ClN3O2/c1-11-9-15(13-5-3-4-6-14(13)20-11)21-18(23)22-16-10-12(19)7-8-17(16)24-2/h3-10H,1-2H3,(H2,20,21,22,23) |
InChIKey: | YBLWOZUPHDKFOT-UHFFFAOYSA-N |
Canonical Smiles: | CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC |
Isomeric Smiles: | CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC |
Molecular Weight: | 341.8 |
Molecular Formula: | C18H16ClN3O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
PQ401
Molecular Weight: | 341.8 |
Molecular Formula: | C18H16ClN3O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 24 |
Complexity: | 437 |
Synonyms
PQ401
| PQ401 | PQ401 |
|---|---|
PQ401 |
196868-63-0 |
PQ 401 |
1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea |
PQ-401 |
IGF-1R Inhibitor II |
TCMDC-125497 |
UNII-2N3LV83S8J |
N-(5-Chloro-2-methoxyphenyl)-N-(2-methyl-4-quinolinyl)urea |
2N3LV83S8J |
CHEMBL439259 |
MFCD00160558 |
K00614a |
GTPL5048 |
SCHEMBL2563976 |
CHEBI:93181 |
DTXSID30173352 |
EX-A549 |
HMS3229G03 |
HMS3266K03 |
HMS3413F12 |
HMS3653J17 |
HMS3677F12 |
BCP06474 |
Urea, N-(5-chloro-2-methoxyphenyl)-N-(2-methyl-4-quinolinyl)- |
WHA86863 |
0143AB |
BDBM50230005 |
N-(2-Methoxy-5-chlorophenyl)-N′-(2-methylquinolin-4-yl)-urea |
s8003 |
ZINC13816309 |
AKOS015950814 |
CCG-206759 |
CS-1386 |
SB19379 |
NCGC00162341-01 |
NCGC00162341-09 |
PQ401, >=98% (HPLC), powder |
AC-30272 |
AS-55838 |
HY-13686 |
FT-0700255 |
SW220120-1 |
J-012727 |
BRD-K67537649-001-01-1 |
Q27088435 |
IGF-1R Inhibitor II, PQ401 - CAS 196868-63-0 |
3-(5-chloro-2-methoxyphenyl)-1-(2-methylquinolin-4-yl)urea |
N-(2-methoxy-5-chlorophenyl)-N-(2-methylquinolin-4-yl)-urea |
N-(2-methoxy-5-chlorophenyl)-N-(2-methylquinolin-4-yl)-urea |
N-(5-Chloro-2-methoxyphenyl)-N-(2-methylquinolin-4-yl)urea" |
Experimental Data
PQ401
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -24.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
PQ401
Statistics Data
PQ401
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -24.000000000000000 | 1 | 1 |
Statistics Data Visualization
PQ401
