Compound Summary
PK 11195
Compound Information
PK 11195
Compound Name: | PK 11195 |
Compound CID: | 1345 |
Synonyms: | PK 11195 85532-75-8 PK11195 PK-11195 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide More... |
Iupac Name: | N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide |
InChI: | InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3 |
InChIKey: | RAVIZVQZGXBOQO-UHFFFAOYSA-N |
Canonical Smiles: | CCC(C)N(C)C(=O)C1=CC2=CC=CC=C2C(=N1)C3=CC=CC=C3Cl |
Isomeric Smiles: | CCC(C)N(C)C(=O)C1=CC2=CC=CC=C2C(=N1)C3=CC=CC=C3Cl |
Molecular Weight: | 352.9 |
Molecular Formula: | C21H21ClN2O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
PK 11195
Molecular Weight: | 352.9 |
Molecular Formula: | C21H21ClN2O |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 25 |
Complexity: | 457 |
Synonyms
PK 11195
| PK 11195 | PK 11195 |
|---|---|
PK 11195 |
85532-75-8 |
PK11195 |
PK-11195 |
1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide |
RP 52028 |
CHEBI:73290 |
N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide |
N-sec-butyl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide |
C21H21ClN2O |
N-(butan-2-yl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide |
N-(sec-Butyl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide |
SMR000058427 |
SR-01000076240 |
85340-56-3 |
Biomol-NT_000287 |
BRN 4264456 |
DSSTox_CID_21097 |
DSSTox_RID_79625 |
DSSTox_GSID_41097 |
Lopac0_000198 |
MLS000028483 |
MLS006010699 |
CHEMBL15313 |
SCHEMBL117124 |
BPBio1_001278 |
CHEMBL481537 |
GTPL8703 |
DTXSID7041097 |
BDBM22032 |
AOB5180 |
HMS2234C05 |
HMS3260H17 |
HMS3266H15 |
HMS3372J02 |
HMS3411O10 |
HMS3675O10 |
HMS3870J13 |
EX-A2448 |
Tox21_300620 |
Tox21_500198 |
MFCD00069334 |
PDSP1_000637 |
PDSP2_000632 |
3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)- |
AKOS024458600 |
CCG-204293 |
LP00198 |
SDCCGSBI-0050186.P002 |
NCGC00015205-03 |
NCGC00015205-04 |
NCGC00015205-05 |
NCGC00015205-06 |
NCGC00015205-07 |
NCGC00015205-08 |
NCGC00015205-14 |
NCGC00024720-02 |
NCGC00024720-03 |
NCGC00024720-04 |
NCGC00254354-01 |
NCGC00260883-01 |
3HPK 11195 |
BM166506 |
HY-19567 |
CAS-85532-75-8 |
CS-0015789 |
EU-0100198 |
FT-0724157 |
PK-11195; RP-52028 |
C 0424 |
1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl) |
Q7119490 |
SR-01000076240-1 |
SR-01000076240-3 |
BRD-A41451487-001-01-3 |
BRD-A41451487-001-04-7 |
1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic acid sec-butyl-methyl-amide |
Experimental Data
PK 11195
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 5.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
PK 11195
Statistics Data
PK 11195
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5.000000000000000 | 1 | 1 |
Statistics Data Visualization
PK 11195
