Compound Summary
PIRFENIDONE
Compound Information
PIRFENIDONE
Compound Name: | PIRFENIDONE |
Compound CID: | 40632 |
Synonyms: | PIRFENIDONE 53179-13-8 5-methyl-1-phenylpyridin-2(1H)-one Esbriet Deskar More... |
Iupac Name: | 5-methyl-1-phenylpyridin-2-one |
InChI: | InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3 |
InChIKey: | ISWRGOKTTBVCFA-UHFFFAOYSA-N |
Canonical Smiles: | CC1=CN(C(=O)C=C1)C2=CC=CC=C2 |
Isomeric Smiles: | CC1=CN(C(=O)C=C1)C2=CC=CC=C2 |
Molecular Weight: | 185.22 |
Molecular Formula: | C12H11NO |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
PIRFENIDONE
Molecular Weight: | 185.22 |
Molecular Formula: | C12H11NO |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 1 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 14 |
Complexity: | 285 |
Synonyms
PIRFENIDONE
| PIRFENIDONE | PIRFENIDONE |
|---|---|
PIRFENIDONE |
53179-13-8 |
5-methyl-1-phenylpyridin-2(1H)-one |
Esbriet |
Deskar |
AMR-69 |
5-Methyl-1-phenyl-2-(1H)-pyridone |
Pirfenidonum |
Pirfenidona |
Pirespa |
2(1H)-Pyridinone, 5-methyl-1-phenyl- |
AMR 69 |
5-methyl-1-phenyl-2(1H)-pyridinone |
5-Methyl-1-phenyl-1H-pyridin-2-one |
5-methyl-1-phenylpyridin-2-one |
5-Methyl-1-phenyl-2(1H)-pyridone |
5-methyl-1-phenyl-2-pyridinone |
UNII-D7NLD2JX7U |
MFCD00866047 |
D7NLD2JX7U |
AMR69 |
CHEBI:32016 |
S-7701 |
NCGC00015806-03 |
DSSTox_CID_25183 |
DSSTox_RID_80731 |
DSSTox_GSID_45183 |
Pirfenidone USAN:INN |
Pirfenidonum INN-Latin |
Pirfenidona INN-Spanish |
CAS-53179-13-8 |
SR-01000076061 |
BRN 1526549 |
Prfendone |
Pirfenidone (JAN/USAN/INN) |
5-methyl-1-phenyl-pyridin-2-one |
Pirfenidone-d3 |
Esbriet (TN) |
Pirfenidone- Bio-X |
Pirfenidone(AMR69) |
KS-5041 |
2(1H)-Pyridone, 5-methyl-1-phenyl- |
Tocris-1093 |
Lopac-P-2116 |
F-647 |
ACMC-209t1g |
P 2116 |
SCHEMBL4708 |
Lopac0_000907 |
5-21-07-00197 (Beilstein Handbook Reference) |
MLS000860042 |
5-Methyl-1-phenyl-2-pyridone |
GTPL7532 |
ZINC1958 |
CHEMBL1256391 |
DTXSID4045183 |
1-phenyl-5-methyl-2-pyridinone |
HSDB 8340 |
Pirfenidone, >=97% (HPLC) |
Bio1_000397 |
Bio1_000886 |
Bio1_001375 |
HMS2234G24 |
HMS3262F16 |
HMS3267I06 |
HMS3372A08 |
HMS3412G13 |
HMS3651P08 |
HMS3676G13 |
AOB31717 |
BCP04473 |
EBD52457 |
HY-B0673 |
Tox21 110225 |
Tox21_110225 |
Tox21_500907 |
5-methyl-1-phenyl-2(1H)pyridinone |
BDBM50005201 |
CP0088 |
NSC748456 |
s2907 |
AKOS006273697 |
S-7701,AMR-69 |
Tox21_110225_1 |
AB07515 |
AC-6797 |
AM84939 |
CCG-204989 |
DB04951 |
LP00907 |
NSC 748456 |
NSC-748456 |
SDCCGSBI-0050882.P002 |
5-methyl-1-phenyl-2-(1H)-pyridinone; |
NCGC00015806-01 |
NCGC00015806-02 |
NCGC00015806-04 |
NCGC00015806-05 |
NCGC00015806-06 |
NCGC00015806-17 |
NCGC00024992-01 |
NCGC00024992-02 |
NCGC00024992-03 |
NCGC00261592-01 |
5-METHYL-N-PHENYL-2-1H-PYRIDONE |
BM164275 |
H960 |
SMR000326900 |
SY034783 |
AB0006721 |
B2288 |
EU-0100907 |
FT-0602686 |
FT-0672092 |
P1871 |
SW220156-1 |
D01583 |
J90039 |
179P138 |
A829431 |
J-523979 |
Q2060696 |
SR-01000076061-1 |
SR-01000076061-3 |
BRD-K96862998-001-03-1 |
BRD-K96862998-001-09-8 |
Pirfenidone, European Pharmacopoeia (EP) Reference Standard |
Experimental Data
PIRFENIDONE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 2.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
PIRFENIDONE
Statistics Data
PIRFENIDONE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2.000000000000000 | 1 | 1 |
Statistics Data Visualization
PIRFENIDONE
