Compound Summary
Noscapine hydrochloride
Compound Information
Noscapine hydrochloride
Compound Name: | Noscapine hydrochloride |
Compound CID: | 9933439 |
Synonyms: | Noscapine hydrochloride Noscapine hydrchloride Noscapine HCl 912-60-7 Narcotine hydrochloride More... |
Iupac Name: | (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride |
InChI: | InChI=1S/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H/t17-,18+;/m1./s1 |
InChIKey: | MFLVZFXCSKVCSH-URBRKQAFSA-N |
Canonical Smiles: | CN1CCC2=CC3=C(C(=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl |
Isomeric Smiles: | CN1CCC2=CC3=C(C(=C2[C@@H]1[C@@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl |
Molecular Weight: | 449.9 |
Molecular Formula: | C22H24ClNO7 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Noscapine hydrochloride
Molecular Weight: | 449.9 |
Molecular Formula: | C22H24ClNO7 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 31 |
Complexity: | 647 |
Synonyms
Noscapine hydrochloride
| Noscapine hydrochloride | Noscapine hydrochloride |
|---|---|
Noscapine hydrochloride |
Noscapine hydrchloride |
Noscapine HCl |
912-60-7 |
Narcotine hydrochloride |
UNII-TTN62ITH9I |
Noscapine (hydrochloride) |
NARCOTINE |
(S)-6,7-dimethoxy-3-((R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-1,3dioxolo4,5-gisoquinolin-5-yl)isobenzofuran-1(3H)-one hydrochloride |
Noscapine hydrochloride hydrate |
TTN62ITH9I |
SR-01000075529 |
3-((5R)-4-methoxy-6-methyl(5,6,7,8-tetrahydro-2H-1,3-dioxoleno4,5-gisoquinol in-5-yl))(3S)-6,7-dimethoxy-3-hydroisobenzofuran-1-one, chloride |
219533-73-0 |
C22H23NO7.HCl |
SCHEMBL177962 |
CHEMBL2106732 |
Tox21_500840 |
HY-13716A |
MFCD00082546 |
SBB006457 |
AKOS024282587 |
CCG-222144 |
LP00840 |
NCGC00261525-01 |
ST057161 |
CS-0013135 |
EU-0100840 |
N0963 |
V1623 |
N 9007 |
912N607 |
SR-01000075529-1 |
SR-01000075529-3 |
Q27290347 |
(3S)-6,7-Dimethoxy-3-(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo4,5-gisoquinolin-5-yl-1(3H)-isobenzofuranone hydrochloride |
Noscapine hydrochloride,(3S)-6,7-Dimethoxy-3-(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo4,5-gisoquinolin-5-yl-1(3H)-isobenzofuranonehydrochloride |
Experimental Data
Noscapine hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -13.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Noscapine hydrochloride
Statistics Data
Noscapine hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -13.000000000000000 | 1 | 1 |
Statistics Data Visualization
Noscapine hydrochloride
