Compound Summary
Naltrexone hydrochloride
Compound Information
Naltrexone hydrochloride
Compound Name: | Naltrexone hydrochloride |
Compound CID: | 5485201 |
Synonyms: | Naltrexone hydrochloride Naltrexone Hcl 16676-29-2 Depade Trexan More... |
Iupac Name: | (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride |
InChI: | InChI=1S/C20H23NO4.ClH/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,15,18,22,24H,1-2,5-10H2;1H/t15-,18+,19+,20-;/m1./s1 |
InChIKey: | RHBRMCOKKKZVRY-ITLPAZOVSA-N |
Canonical Smiles: | C1CC1CN2CCC34C5C(=O)CCC3(C2CC6=C4C(=C(C=C6)O)O5)O.Cl |
Isomeric Smiles: | C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl |
Molecular Weight: | 377.9 |
Molecular Formula: | C20H24ClNO4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Naltrexone hydrochloride
Molecular Weight: | 377.9 |
Molecular Formula: | C20H24ClNO4 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 26 |
Complexity: | 621 |
Synonyms
Naltrexone hydrochloride
| Naltrexone hydrochloride | Naltrexone hydrochloride |
|---|---|
Naltrexone hydrochloride |
Naltrexone Hcl |
16676-29-2 |
Depade |
Trexan |
Antaxone |
ReVia |
Naltrexone (Hydrochloride) |
NIH 8503 |
EN-1639A |
UNII-Z6375YW9SF |
Celupan |
Nemexin |
Vivitrol |
N-Cyclopropylmethyl-noroxymorphone hydrochloride |
MLS000069607 |
Naltrexone hydrochloride USP |
Z6375YW9SF |
Vivitrex |
MFCD00069324 |
(5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride |
17-(Cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-one hydrochloride |
Nalorex |
SMR000058767 |
En 1639A |
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro3,2-eisoquinolin-7-one;hydrochloride |
Naltrexone hydrochloride (USP) |
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride (1:1), (5alpha)- |
CCRIS 1168 |
EINECS 240-723-0 |
Naltrel |
naltrexone.HCl |
Naltrexone Depot |
Prestwick_348 |
ReVia (TN) |
XR-NTX |
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro3,2-eisoquinoline-7-one;hydrochloride |
Opera_ID_1828 |
naltrexone monohydrochloride |
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-, hydrochloride |
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride, (5-alpha)- |
SCHEMBL37713 |
MLS001076516 |
MLS002153483 |
MLS002695940 |
CYTO-205 |
CHEMBL1201149 |
AOB5051 |
DTXSID50937236 |
PTI-901 |
17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride |
CHEBI:134687 |
BCP08343 |
EBD53136 |
s2103 |
VP-004 |
AKOS015994597 |
CCG-268383 |
CS-0763 |
HS-0003 |
MCULE-8888771893 |
NC00693 |
17-Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride |
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-alpha-oxy-3,14-dihydoxy-, hydrochloride |
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride, (5alpha)- |
BN164635 |
HY-76710 |
SW196619-3 |
N-Cyclopropylmethylnoroxymorphone hydrochloride |
D02095 |
H10489 |
676N292 |
Q27096434 |
Z1558290144 |
Naltrexone Hydrochloride 1.0 mg/ml in Methanol (as free base) |
Naltrexone hydrochloride, European Pharmacopoeia (EP) Reference Standard |
(5a)-17-(Cyclopropyl-methyl-d3)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride |
(5a)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-morphinan-6-one hydrochloride |
17-(cyclopropylmethyl)-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one hydrochloride |
(1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo9.6.1.0^{1,13}.0^{5,17}.0^{7,18}octadeca-7(18),8,10-trien-14-one hydrochloride |
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro3,2-eisoquinolin-7(7aH)-one hydrochloride |
(4R,4As,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro3,2-eisoquinolin-7-one;hydron;chloride |
(5alpha,17R)-17-(cyclopropylmethyl)-3,14-dihydroxy-6-oxo-4,5-epoxymorphinan-17-ium chloride |
Experimental Data
Naltrexone hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -6.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Naltrexone hydrochloride
Statistics Data
Naltrexone hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6.000000000000000 | 1 | 1 |
Statistics Data Visualization
Naltrexone hydrochloride
