Compound Summary
Naloxone hydrochloride
Compound Information
Naloxone hydrochloride
Compound Name: | Naloxone hydrochloride |
Compound CID: | 5464092 |
Synonyms: | Naloxone hydrochloride Naloxone HCl 357-08-4 Narcan Naloxone (hydrochloride) More... |
Iupac Name: | (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride |
InChI: | InChI=1S/C19H21NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;/h2-4,14,17,21,23H,1,5-10H2;1H/t14-,17+,18+,19-;/m1./s1 |
InChIKey: | RGPDIGOSVORSAK-STHHAXOLSA-N |
Canonical Smiles: | C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl |
Isomeric Smiles: | C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl |
Molecular Weight: | 363.8 |
Molecular Formula: | C19H22ClNO4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Naloxone hydrochloride
Molecular Weight: | 363.8 |
Molecular Formula: | C19H22ClNO4 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 25 |
Complexity: | 594 |
Synonyms
Naloxone hydrochloride
| Naloxone hydrochloride | Naloxone hydrochloride |
|---|---|
Naloxone hydrochloride |
Naloxone HCl |
357-08-4 |
Narcan |
Naloxone (hydrochloride) |
NIH 7890 |
UNII-F850569PQR |
EN-15304 |
CHEBI:31892 |
F850569PQR |
MFCD00069322 |
357-08-4 (HCl) |
Narcanti |
17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride |
(4R,4AS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro3,2-eisoquinolin-7(7aH)-one hydrochloride |
Nalonee |
Evzio |
MLS000069540 |
Naloxonehydrochloride |
SMR000058766 |
Prestwick_879 |
EINECS 206-611-0 |
Narcan (TN) |
Evzio (TN) |
Nafoxone Hydrochloride |
nal-oxon hydrochloride |
Naloxone hydrochloride USAN:USP:JAN |
EN 15304 |
CHEMBL1718 |
C19H21NO4.HCl |
SCHEMBL41390 |
l-N-Allyl-14-hydroxynordihydromorphinone hydrochloride |
(-)-N-Allyl-14-hydroxynordihydromorphinone hydrochloride |
DTXSID70957097 |
HMS1568G04 |
ACT02626 |
Naloxone hydrochloride (JP17/USP) |
(5a)-17-allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride |
17-Allyl-4,5-alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride |
Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, hydrochloride, (-)- |
s3066 |
(5alpha)-17-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride |
AKOS024418753 |
Morphinan-6-one, 17-allyl-4,5-alpha-epoxy-3,14-dihydroxy-, hydrochloride |
ACN-032222 |
CCG-220111 |
CS-1335 |
KS-5379 |
MCULE-7328605584 |
NC00587 |
NSC 757109 |
H859 |
HY-17417 |
SW197001-3 |
D01340 |
357N084 |
SR-01000597918 |
SR-01000737374 |
SR-01000597918-1 |
SR-01000737374-3 |
W-106655 |
Q27114711 |
(5alpha)-17-allyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one hydrochloride |
17-allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one hydrochloride |
(17R)-17-allyl-3,14-dihydroxy-6-oxo-4,5alpha-epoxymorphinan-17-ium chloride |
(5?)-4,5-Epoxy-3,14-dihydro-17-(2-propenyl)morphinan-6-one hydrochloride |
(5a)-4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-morphinan-6-one hydrochloride |
(5alpha)-4,5-Epoxy-3,14-dihydro-17-(2-propenyl)morphinan-6-one hydrochloride |
(5alpha,17R)-17-allyl-3,14-dihydroxy-6-oxo-4,5-epoxymorphinan-17-ium chloride |
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5alpha)- |
(4R,4As,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro3,2-eisoquinolin-7-one;hydrochloride |
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro3,2-eisoquinolin-7-one;hydrochloride |
(5alpha)-4,5-Epoxy-3,14-dihydro-17-(2-pr openyl)morphinan-6-one hydrochloride" |
Experimental Data
Naloxone hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 4.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Naloxone hydrochloride
Statistics Data
Naloxone hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 4.000000000000000 | 1 | 1 |
Statistics Data Visualization
Naloxone hydrochloride
