Compound Summary
NCS-356
Compound Information
NCS-356
Compound Name: | NCS-356 |
Compound CID: | 5794315 |
Synonyms: | NCS-356 (E)-4-(4-chlorophenyl)-4-hydroxybut-2-enoic acid (2E)-4-(4-Chlorophenyl)-4-hydroxy-2-butenoic acid 99389-57-8 NCS-356 parent More... |
Iupac Name: | (E)-4-(4-chlorophenyl)-4-hydroxybut-2-enoic acid |
InChI: | InChI=1S/C10H9ClO3/c11-8-3-1-7(2-4-8)9(12)5-6-10(13)14/h1-6,9,12H,(H,13,14)/b6-5+ |
InChIKey: | FPLZDFIDWYDARU-AATRIKPKSA-N |
Canonical Smiles: | C1=CC(=CC=C1C(C=CC(=O)O)O)Cl |
Isomeric Smiles: | C1=CC(=CC=C1C(/C=C/C(=O)O)O)Cl |
Molecular Weight: | 212.63 |
Molecular Formula: | C10H9ClO3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
NCS-356
Molecular Weight: | 212.63 |
Molecular Formula: | C10H9ClO3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 14 |
Complexity: | 219 |
Synonyms
NCS-356
| NCS-356 | NCS-356 |
|---|---|
NCS-356 |
(E)-4-(4-chlorophenyl)-4-hydroxybut-2-enoic acid |
(2E)-4-(4-Chlorophenyl)-4-hydroxy-2-butenoic acid |
99389-57-8 |
NCS-356 parent |
Lopac0_000807 |
SCHEMBL6505684 |
SCHEMBL6505688 |
CHEMBL1255938 |
DTXSID8048448 |
SDCCGSBI-0050784.P002 |
Q27261068 |
2-Butenoic acid, 4-(4-chlorophenyl)-4-hydroxy-, (2E)- |
Experimental Data
NCS-356
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -2.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
NCS-356
Statistics Data
NCS-356
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -2.000000000000000 | 1 | 1 |
Statistics Data Visualization
NCS-356
