Compound Summary
Milnacipran hydrochloride
Compound Information
Milnacipran hydrochloride
Compound Name: | Milnacipran hydrochloride |
Compound CID: | 163701 |
Synonyms: | Milnacipran hydrochloride Milnacipran HCl 101152-94-7 Dalcipran Savella More... |
Iupac Name: | (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide;hydrochloride |
InChI: | InChI=1S/C15H22N2O.ClH/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12;/h5-9,13H,3-4,10-11,16H2,1-2H3;1H/t13-,15+;/m1./s1 |
InChIKey: | XNCDYJFPRPDERF-PBCQUBLHSA-N |
Canonical Smiles: | CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2.Cl |
Isomeric Smiles: | CCN(CC)C(=O)[C@@]1(C[C@@H]1CN)C2=CC=CC=C2.Cl |
Molecular Weight: | 282.81 |
Molecular Formula: | C15H23ClN2O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Milnacipran hydrochloride
Molecular Weight: | 282.81 |
Molecular Formula: | C15H23ClN2O |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 19 |
Complexity: | 295 |
Synonyms
Milnacipran hydrochloride
| Milnacipran hydrochloride | Milnacipran hydrochloride |
|---|---|
Milnacipran hydrochloride |
Milnacipran HCl |
101152-94-7 |
Dalcipran |
Savella |
Milnacipran (hydrochloride) |
(1R-cis)-Milnacipran Hydrochloride |
F 2207 |
SMR000449266 |
Midalcipran hydrochloride |
F2207 |
Milnacipran hydrochloride USAN |
Toledomin (TN) |
Savella (TN) |
NCGC00168780-01 |
1-Phenyl-1-(diethylaminocarbonyl)-2-(aminomethyl)cyclopropane hydrochloride |
cis-(+-)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide monohydrochloride |
DSSTox_CID_26785 |
DSSTox_RID_81903 |
DSSTox_GSID_46785 |
MLS000758229 |
MLS001424149 |
SCHEMBL161558 |
CHEMBL1237129 |
DTXSID4046785 |
CHEBI:31854 |
HY-B0168A |
AOB6178 |
AMY22199 |
BCP05817 |
Tox21_112641 |
s3140 |
Milnacipran hydrochloride (JAN/USAN) |
AKOS015950801 |
CCG-101034 |
CS-2010 |
KS-1274 |
NC00284 |
NSC 759806 |
(1R,2S)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide Hydrochloride |
Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, monohydrochloride, cis-(+-)- |
Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, monohydrochloride, (1R,2S)-rel- |
AB0108218 |
CAS-101152-94-7 |
SW197664-2 |
D01107 |
Milnacipran hydrochloride, >=98% (HPLC), solid |
J-011063 |
Q27288221 |
UNII-RNZ43O5WW5 component XNCDYJFPRPDERF-PBCQUBLHSA-N |
Z-2 Aminomethyl-1-phenyl-N,N-diethylcyclopropane-carboxamide hydrochloride |
(1RS,2SR)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride |
Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, hydrochloride (1:1), (1R,2S)-rel- |
Milnacipran hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material |
Experimental Data
Milnacipran hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20.000000000000000 | umol/L | 44.630000000000000 | 42.960000000000000 | -3.751000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.170000000000000 | 44.910000000000000 | 4.025000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 17.370000000000000 | 16.630000000000000 | -4.243000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 15.860000000000000 | 15.610000000000000 | -1.604000000000000 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
Milnacipran hydrochloride
Statistics Data
Milnacipran hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -1.604000000000000 | 1 | 2 | |
| Drosophila melanogaster | 4.025000000000000 | 1 | 2 |
Statistics Data Visualization
Milnacipran hydrochloride
