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Compound Summary

Mexiletine hydrochloride

Compound Information

Mexiletine hydrochloride

Compound Name:	Mexiletine hydrochloride
Compound CID:	21467
Synonyms:	Mexiletine hydrochloride 5370-01-4 Mexiletine HCL Mexitil Mexiletene hydrochloride More...
Iupac Name:	1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride
InChI:	InChI=1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H
InChIKey:	NFEIBWMZVIVJLQ-UHFFFAOYSA-N
Canonical Smiles:	CC1=C(C(=CC=C1)C)OCC(C)N.Cl
Isomeric Smiles:	CC1=C(C(=CC=C1)C)OCC(C)N.Cl
Molecular Weight:	215.72
Molecular Formula:	C11H18ClNO

Compound Structure

2D Structure:

3D Structure:

Computed Properties

Mexiletine hydrochloride

Molecular Weight:	215.72
Molecular Formula:	C11H18ClNO
Hydrogen Bond Donor Count:	2
Hydrogen Bond Acceptor Count:	2
Rotatable Bond Count:	3
Heavy Atom Count:	14
Complexity:	139

Synonyms

Mexiletine hydrochloride

Mexiletine hydrochloride	Mexiletine hydrochloride
Mexiletine hydrochloride	5370-01-4
Mexiletine HCL	Mexitil
Mexiletene hydrochloride	Mexiletine (hydrochloride)
1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride	1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride
2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride	KOE-1173 (hydrochloride)
Ko 1173 Cl	KO1173
MFCD00216024	1-Methyl-2-(2,6-xylyloxy)ethylammonium chloride
1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride	2-(2-aminopropoxy)-1,3-dimethylbenzene hydrochloride
Ethylamine, 1-methyl-2-(2,6-xylyloxy)-, hydrochloride	NCGC00094121-01
DSSTox_CID_25783	DSSTox_RID_81125
DSSTox_GSID_45783	1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride
1-(2,6-Dimethylphenoxy)-2-aminopropane hydrochloride	CHEBI:6917
(+-)-1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride	SMR000326711
CAS-5370-01-4	1-(2,6-Xylyloxy)-2-aminopropane
1-(2,6-dimethylphenoxy)prop-2-ylamine, chloride	SR-01000075986
NCGC00015659-06	KO 1173
(2S)-1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride	Mexiletine, HCl
UNII-606D60IS38	Prestwick_666
EINECS 226-362-1	Mexitil (TN)
KO-1173	606D60IS38
1-(2,6-Xylyloxy)-2-aminopropane hydrochloride	SCHEMBL42226
MLS001056756	MLS002222239
MLS002548872	SPECTRUM1503929
1-(2,6-Dimethylphenoxy)-2-propylamine Hydrochloride	MEXILITENE HYDROCHLORIDE
Mexiletine hydrochloride, powder	CHEMBL1200606
DTXSID2045783	KO-1173-Cl
HMS1568B04	KO-1173 CL
Pharmakon1600-01503929	2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride, (+-)-
BCP28602	EBD30089
HY-A0093	Tox21_111249
Tox21_500784	NSC758639
s4225	SBB003392
Mexiletine hydrochloride (JP17/USP)	AKOS009139802
Tox21_111249_1	Tox21_111249_2
AC-4260	AC-8240
CCG-213246	LP00784
MCULE-4507699259	NC00682
NSC 758639	NSC-758639
VA11290	NCGC00015659-14
NCGC00094121-02	NCGC00094121-03
NCGC00094121-04	NCGC00261469-01
5370-01-4 (HCl)	AS-13790
Mexiletine hydrochloride USAN:USP:JAN	ST083488
1-(2,6-Dimethylphenoxy)-2-propanamine HCl	EU-0100784
FT-0672397	FT-0672398
M2040	SW196821-3
V0364	EN300-53944
D00639	J10321
M 2727	370M014
A829739	Mexiletine HCl;KO-1173; KO 1173; KO1173
SR-01000075986-1	SR-01000075986-6
W-105713	Q27107357
1-(2,6-dimethylphenoxy)-2-amino-propane hydrochloride;	1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride, 97%
Mexiletine hydrochloride, European Pharmacopoeia (EP) Reference Standard	Mexiletine hydrochloride, United States Pharmacopeia (USP) Reference Standard

Experimental Data

Mexiletine hydrochloride

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	33.000000000000000	umol/L			-5.000000000000000				NS	N2		24134630	Inactive

Experimental Data Visualization

Mexiletine hydrochloride

Statistics Data

Mexiletine hydrochloride

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	-5.000000000000000		1	1

Statistics Data Visualization

Mexiletine hydrochloride

Compound Name:

Mexiletine hydrochloride

Compound CID:

21467

Synonyms:

Mexiletine hydrochloride 5370-01-4 Mexiletine HCL Mexitil Mexiletene hydrochloride More...

Iupac Name:

1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride

InChI:

InChI=1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H

InChIKey:

NFEIBWMZVIVJLQ-UHFFFAOYSA-N

Canonical Smiles:

CC1=C(C(=CC=C1)C)OCC(C)N.Cl

Isomeric Smiles:

CC1=C(C(=CC=C1)C)OCC(C)N.Cl

Molecular Weight:

215.72

Molecular Formula:

C11H18ClNO

Molecular Weight:

215.72

Molecular Formula:

C11H18ClNO

Hydrogen Bond Donor Count:

2

Hydrogen Bond Acceptor Count:

2

Rotatable Bond Count:

3

Heavy Atom Count:

14

Complexity:

139

Mexiletine hydrochloride

5370-01-4

Mexiletine HCL

Mexitil

Mexiletene hydrochloride

Mexiletine (hydrochloride)

1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride

1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride

2-Propanamine, 1-(2,6-dimethylphenoxy)-, hydrochloride

KOE-1173 (hydrochloride)

Ko 1173 Cl

KO1173

MFCD00216024

1-Methyl-2-(2,6-xylyloxy)ethylammonium chloride

1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride

2-(2-aminopropoxy)-1,3-dimethylbenzene hydrochloride

Ethylamine, 1-methyl-2-(2,6-xylyloxy)-, hydrochloride

NCGC00094121-01

DSSTox_CID_25783

DSSTox_RID_81125

DSSTox_GSID_45783

1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride

1-(2,6-Dimethylphenoxy)-2-aminopropane hydrochloride

CHEBI:6917

(+-)-1-Methyl-2-(2,6-xylyloxy)ethylamine hydrochloride

SMR000326711

CAS-5370-01-4

1-(2,6-Xylyloxy)-2-aminopropane

1-(2,6-dimethylphenoxy)prop-2-ylamine, chloride

SR-01000075986

NCGC00015659-06

KO 1173

(2S)-1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride

Mexiletine, HCl

UNII-606D60IS38

Prestwick_666

EINECS 226-362-1

Mexitil (TN)

KO-1173

606D60IS38

1-(2,6-Xylyloxy)-2-aminopropane hydrochloride

SCHEMBL42226

MLS001056756

MLS002222239

MLS002548872

SPECTRUM1503929

Mexiletine hydrochloride

5370-01-4

Mexiletine HCL

Mexitil

Mexiletene hydrochloride

More...