Compound Summary
METYROSINE
Compound Information
METYROSINE
Compound Name: | METYROSINE |
Compound CID: | 441350 |
Synonyms: | METYROSINE 672-87-7 alpha-Methyl-L-tyrosine Metirosine Demser More... |
Iupac Name: | (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid |
InChI: | InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1 |
InChIKey: | NHTGHBARYWONDQ-JTQLQIEISA-N |
Canonical Smiles: | CC(CC1=CC=C(C=C1)O)(C(=O)O)N |
Isomeric Smiles: | C[C@](CC1=CC=C(C=C1)O)(C(=O)O)N |
Molecular Weight: | 195.21 |
Molecular Formula: | C10H13NO3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
METYROSINE
Molecular Weight: | 195.21 |
Molecular Formula: | C10H13NO3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 14 |
Complexity: | 211 |
Synonyms
METYROSINE
| METYROSINE | METYROSINE |
|---|---|
METYROSINE |
672-87-7 |
alpha-Methyl-L-tyrosine |
Metirosine |
Demser |
(S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid |
(S)-alpha-Methyltyrosine |
Methyltyrosine |
alpha-Methyltyrosine |
L-alpha-Methyltyrosine |
L-alpha-Methyl-p-tyrosine |
Metirosinum |
Metirosina |
Alpha-Methyl-L-P-Tyrosine |
(2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid |
(-)-alpha-Methyl-L-tyrosine |
UNII-DOQ0J0TPF7 |
MK-781 |
alpha-Methyl-para-tyrosine |
DOQ0J0TPF7 |
ALPHA-METHYL-L-TYR |
CHEBI:6912 |
MFCD00064201 |
NCGC00094144-03 |
DSSTox_CID_3315 |
DSSTox_RID_76972 |
DSSTox_GSID_23315 |
L-588357-0 |
alpha-MPT |
CAS-672-87-7 |
(R)-alpha-Methyltyrosine |
alpha-methyl-paratyrosine |
Metyrosine USAN:USP |
Metirosinum INN-Latin |
MK 781 |
Metirosina INN-Spanish |
L-2-ME-TYR-OH |
alpha-Me-Tyr-OH |
Metirosine INN |
Metyrosine (USP) |
EINECS 211-599-5 |
Demser (TN) |
a-methyl-L-p-tyrosine |
L-AMPT |
Metirosine (JAN/INN) |
Spectrum3_001846 |
H-(ME)TYR-OH |
A-METHYL-L-TYROSINE |
(S)-2-(4-Hydroxybenzyl)-2-aminopropanoic Acid |
Lopac0_000811 |
SCHEMBL50398 |
BSPBio_003232 |
ZINC693 |
SPECTRUM2300312 |
a-Methyltyrosinea-Methyltyrosine |
GTPL6956 |
L 588357-0 |
CHEMBL1200862 |
DTXSID6023315 |
KBio3_002732 |
(-)-(S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropionsaeure |
HMS3262D03 |
L-Tyrosine, alpha-methyl-, (-)- |
Tox21_111253 |
Tox21_500811 |
s5797 |
AKOS016844271 |
Tox21_111253_1 |
AB02561 |
AM83582 |
CCG-204895 |
CS-W015723 |
DB00765 |
HY-W015007 |
LP00811 |
MCULE-5340647798 |
SDCCGSBI-0050788.P002 |
NCGC00015701-06 |
NCGC00094144-01 |
NCGC00094144-04 |
NCGC00094144-05 |
NCGC00094144-06 |
NCGC00094144-07 |
NCGC00094144-11 |
NCGC00261496-01 |
AC-32982 |
alpha-Methyl-L-tyrosine, >=98% (TLC) |
AS-47139 |
L-2-Methyl-3-(4-hydroxy-phenyl)alanine |
EU-0100811 |
C07921 |
D00762 |
F12275 |
L-2-METHYL-3-(4-HYDROXYPHENYL)ALANINE |
M 8131 |
672M877 |
A835693 |
Q6824116 |
Z1617901128 |
(2S)-2-amino-3-(4-hydroxyphenyl)-2-methyl-propanoic acid |
UNII-X88TTO174Z component NHTGHBARYWONDQ-JTQLQIEISA-N |
Metyrosine, United States Pharmacopeia (USP) Reference Standard |
(S)-a-Methyl-4-hydroxy phenylalanine, (S)-a-Methyltyrosine (>98%, >98%ee) |
Experimental Data
METYROSINE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -1.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
METYROSINE
Statistics Data
METYROSINE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -1.000000000000000 | 1 | 1 |
Statistics Data Visualization
METYROSINE
