Compound Summary
MEMANTINE HYDROCHLORIDE
Compound Information
MEMANTINE HYDROCHLORIDE
Compound Name: | MEMANTINE HYDROCHLORIDE |
Compound CID: | 181458 |
Synonyms: | MEMANTINE HYDROCHLORIDE 41100-52-1 Memantine HCL Namenda 3,5-Dimethyl-1-adamantanamine hydrochloride More... |
Iupac Name: | 3,5-dimethyladamantan-1-amine;hydrochloride |
InChI: | InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H |
InChIKey: | LDDHMLJTFXJGPI-UHFFFAOYSA-N |
Canonical Smiles: | CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl |
Isomeric Smiles: | CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl |
Molecular Weight: | 215.76 |
Molecular Formula: | C12H22ClN |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
MEMANTINE HYDROCHLORIDE
Molecular Weight: | 215.76 |
Molecular Formula: | C12H22ClN |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 1 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 14 |
Complexity: | 240 |
Synonyms
MEMANTINE HYDROCHLORIDE
| MEMANTINE HYDROCHLORIDE | MEMANTINE HYDROCHLORIDE |
|---|---|
MEMANTINE HYDROCHLORIDE |
41100-52-1 |
Memantine HCL |
Namenda |
3,5-Dimethyl-1-adamantanamine hydrochloride |
3,5-dimethyladamantan-1-amine hydrochloride |
Akatinol |
Axura |
Namenda XR |
memantine.HCl |
Memantine (hydrochloride) |
1-Amino-3,5-dimethyladamantane Hydrochloride |
UNII-JY0WD0UA60 |
3,5-dimethyladamantan-1-amine;hydrochloride |
JY0WD0UA60 |
Ebixa |
CHEBI:64323 |
MFCD00214336 |
3,5-dimethyladamantan-1-aminium chloride |
D-145 |
MLS001332605 |
3,5-Dimethyl-1-aminoadamantane hydrochloride |
SUN-Y7017 |
(3,5-Dimethyl-1-adamantyl)amine hydrochloride |
3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine hydrochloride |
1,3-Dimethyl-5-adamantanamine HCl |
NSC-102290 |
3,5-dimethyltricyclo3.3.1.13,7decan-1-amine hydrochloride |
41100-52-1 (HCl) |
D 145 |
Mantine |
Ebixza |
3,5-Dimethyl-tricyclo3.3.1.13,7decan-1-amine hydrochloride |
3,5-Dimethyltricyclo(3.3.1.13,7)decan-1-amine hydrochloride |
3,5-dimethyladamantanylamine, chloride |
3,5-Dimethyl-1-adamantylamine |
3,5-Dimethyl-1-aminoadamantane |
SMR000875213 |
SR-01000075458 |
Memary |
Memantine hydrochloride USAN |
SUN Y7017 |
EINECS 255-219-6 |
Namenda (TN) |
Memary (TN) |
Memantin hydrochloride |
NSC 102290 |
ACMC-209jif |
D-145 (hydrochloride) |
SCHEMBL3053 |
C12H21N.HCl |
CHEMBL1699 |
MLS001332606 |
SPECTRUM1501121 |
HY-B0365A |
AOB5318 |
DTXSID90961439 |
Memantine hydrochloride (Namenda) |
N06DX01 |
NMI-131 |
FP-01 |
HMS1571C17 |
HMS1921H03 |
Pharmakon1600-01501121 |
Memantine hydrochloride (JAN/USP) |
3,5-Dimethylamantadine hydrochloride |
Tox21_500861 |
AC-559 |
CCG-39018 |
MRZ-2/145 |
NSC102290 |
NSC757843 |
s2043 |
SBB003390 |
Tricyclo3.3.1.13,7decan-1-amine, 3,5-dimethyl-, hydrochloride |
AKOS015889460 |
BCP9000253 |
LP00861 |
MCULE-6635165082 |
NC00680 |
NSC-757843 |
NCGC00094186-01 |
NCGC00094186-02 |
NCGC00094186-03 |
NCGC00261546-01 |
AS-13331 |
BM164662 |
H908 |
ST088119 |
SY057917 |
AB0013351 |
AM20070534 |
D3608 |
EU-0100861 |
FT-0650723 |
M-145 |
SW060653-4 |
1-amino-3,5-dimethyl-adamantane hydrochloride |
3,5-dimethyladamantan-1-amine hy-drochloride |
3,5-dimethyladamantan-1-amine;hydrochloride. |
D04905 |
J10287 |
M 9292 |
SR-01000075458-1 |
SR-01000075458-3 |
SR-01000075458-8 |
Q27133218 |
Z1551429722 |
3,5-Dimethyltricyclo(3.3.1.1(sup 3,7))decan-1-amine hydrochloride |
Tricyclo(3.3.1.1(3,7))decan-1-amine, 3,5-dimethyl-, hydrochloride |
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine, 3,5-dimethyl-, hydrochloride |
Experimental Data
MEMANTINE HYDROCHLORIDE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20.000000000000000 | umol/L | 44.630000000000000 | 43.630000000000000 | -2.248000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.170000000000000 | 43.700000000000000 | 1.239000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -5.000000000000000 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 15.650000000000000 | 17.090000000000000 | 9.196000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 17.370000000000000 | 17.420000000000000 | 0.276700000000000 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
MEMANTINE HYDROCHLORIDE
Statistics Data
MEMANTINE HYDROCHLORIDE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 9.196000000000000 | 2 | 3 | |
| Drosophila melanogaster | 1.239000000000000 | 1 | 2 |
Statistics Data Visualization
MEMANTINE HYDROCHLORIDE
