Compound Summary
Loxoprofen
Compound Information
Loxoprofen
Compound Name: | Loxoprofen |
Compound CID: | 3965 |
Synonyms: | Loxoprofen 68767-14-6 2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid Loxoprofene Loxoprofeno More... |
Iupac Name: | 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoic acid |
InChI: | InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18) |
InChIKey: | YMBXTVYHTMGZDW-UHFFFAOYSA-N |
Canonical Smiles: | CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O |
Isomeric Smiles: | CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O |
Molecular Weight: | 246.3 |
Molecular Formula: | C15H18O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Loxoprofen
Molecular Weight: | 246.3 |
Molecular Formula: | C15H18O3 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 18 |
Complexity: | 316 |
Synonyms
Loxoprofen
| Loxoprofen | Loxoprofen |
|---|---|
Loxoprofen |
68767-14-6 |
2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid |
Loxoprofene |
Loxoprofeno |
Koloxo |
Loxoprofenum |
Loxoprofen sodium |
Loxoprofen INN |
2-4-(2-oxocyclopentyl)methylphenylpropanoic acid |
2-{4-(2-oxocyclopentyl)methylphenyl}propanoic acid |
UNII-3583H0GZAP |
MFCD00864331 |
CHEMBL19299 |
3583H0GZAP |
Loxoprofen sodium hydrate |
CHEBI:76172 |
CS-600 |
sodium loxoprofen |
Loxoprofen (INN) |
Oxeno |
NCGC00015594-02 |
DSSTox_CID_25164 |
DSSTox_RID_80714 |
DSSTox_GSID_45164 |
Loxoprofene French |
Loxoprofenum Latin |
2-(4-((2-Oxocyclopentyl)methyl)-phenyl)propanoic acid |
Loxoprofeno Spanish |
yl-propionic acid |
CAS-68767-14-6 |
2-4-(2-Oxo-cyclopentylmethyl)-phen |
Loxoprofen, solid |
80382-23-6 |
Lopac0_000677 |
SCHEMBL24423 |
C15H17NaO3 |
(+-)-p-((2-Oxocyclopentyl)methyl)hydratropic acid |
DTXSID1045164 |
alpha-Methyl-4-(2-oxocyclopentyl)methylbenzeneacetic acid |
HMS3262G15 |
HMS3885N16 |
Loxoprofen (low-melting polymorph) |
BCP10971 |
EBD24378 |
HY-B0578 |
Loxoprofen (high-melting polymorph) |
Tox21_110178 |
Tox21_500677 |
BDBM50140320 |
s4682 |
AKOS015906359 |
Tox21_110178_1 |
AC-8108 |
AT-7141 |
CCG-204763 |
DB09212 |
GS-3193 |
LP00677 |
SDCCGSBI-0050656.P002 |
NCGC00015594-03 |
NCGC00015594-04 |
NCGC00015594-08 |
NCGC00094037-01 |
NCGC00094037-02 |
NCGC00261362-01 |
NCGC00263577-01 |
AC-15776 |
H883 |
SY113439 |
AB0012364 |
DB-055188 |
EU-0100677 |
FT-0641207 |
L0244 |
CS-600; CS600; CS 600 |
D08149 |
L 0664 |
(+-)-((2-oxocyclopentyl)methyl)hydratropic acid |
767L146 |
A836244 |
SR-01000075955 |
Q-201324 |
Q-300011 |
Q2759348 |
SR-01000075955-1 |
2-4-(2-Oxocyclopentyl)methylphenylpropionic Acid |
2-4-(2-Oxo-cyclopentylmethyl)-phenyl-propionic acid |
2-4-(2-oxocyclopentan-1-ylmethyl)phenylpropionic acid |
2-4-(2-Oxocyclopentan-1-ylmethyl)phenyl-propionic Acid |
Benzeneacetic acid, alpha-methyl-4-((2-oxocyclopentyl)methyl)- |
Benzeneacetic acid, .alpha.-methyl-4-(2-oxocyclopentyl)methyl- |
Experimental Data
Loxoprofen
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -5.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Loxoprofen
Statistics Data
Loxoprofen
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5.000000000000000 | 1 | 1 |
Statistics Data Visualization
Loxoprofen
