Compound Summary
Loxapine succinate
Compound Information
Loxapine succinate
Compound Name: | Loxapine succinate |
Compound CID: | 71399 |
Synonyms: | Loxapine succinate 27833-64-3 Loxapine succinate salt Loxapac Cloxazepin More... |
Iupac Name: | butanedioic acid;8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine |
InChI: | InChI=1S/C18H18ClN3O.C4H6O4/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18;5-3(6)1-2-4(7)8/h2-7,12H,8-11H2,1H3;1-2H2,(H,5,6)(H,7,8) |
InChIKey: | YQZBAXDVDZTKEQ-UHFFFAOYSA-N |
Canonical Smiles: | CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.C(CC(=O)O)C(=O)O |
Isomeric Smiles: | CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.C(CC(=O)O)C(=O)O |
Molecular Weight: | 445.9 |
Molecular Formula: | C22H24ClN3O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Loxapine succinate
Molecular Weight: | 445.9 |
Molecular Formula: | C22H24ClN3O5 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 31 |
Complexity: | 542 |
Synonyms
Loxapine succinate
| Loxapine succinate | Loxapine succinate |
|---|---|
Loxapine succinate |
27833-64-3 |
Loxapine succinate salt |
Loxapac |
Cloxazepin |
Daxolin |
Loxapine (succinate) |
UNII-X59SG0MRYU |
Loxapine,succinate |
CL 71563 |
X59SG0MRYU |
CPD000058470 |
C22H24ClN3O5 |
MLS000069383 |
Butanedioic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenzb,f1,4oxazepine (1:1) |
MFCD00069298 |
NCGC00016160-02 |
Lederle |
SMR000058470 |
CAS-27833-64-3 |
DSSTox_CID_25227 |
DSSTox_RID_80764 |
DSSTox_GSID_45227 |
CL-71563 |
2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine succinate (1:1) |
2-Chloro-11-(4-methylpiperazin-1-yl)dibenzob,f1,4oxazepine succinate |
CHEBI:6549 |
butanedioic acid;8-chloro-6-(4-methylpiperazin-1-yl)benzob1,4benzoxazepine |
Butanedioic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine (1:1) |
CCRIS 1917 |
AZ-004 |
SR-01000002971 |
EINECS 248-682-0 |
Loxapine succinate USAN:USP |
Staccato-loxapine |
Loxitane (TN) |
Prestwick_304 |
Lopac-L-106 |
Opera_ID_1518 |
Loxapine succinate (USP) |
2-chloro-11-(4-methyl-1-piperazinyl)dibenzob,f1,4oxazepine succinate |
SCHEMBL41643 |
MAPROTILINEHYDROCHLORIDE |
MLS000758291 |
MLS001146961 |
MLS001401432 |
MLS002222201 |
SPECTRUM2300242 |
Loxapine succinate salt, solid |
REGID_for_CID_71399 |
CHEMBL1201155 |
DTXSID3045227 |
AOB5330 |
HMS1568K06 |
HMS1922L14 |
HMS2051E05 |
HMS2093N20 |
HMS2095K06 |
HMS2232N05 |
HMS3262O21 |
HMS3374F02 |
HMS3393E05 |
HMS3652O10 |
HMS3712K06 |
HMS3885H03 |
Pharmakon1600-02300242 |
Tox21_110311 |
Tox21_500720 |
AZ-104 |
CCG-39497 |
HY-17390A |
NSC759578 |
s4086 |
AKOS015994711 |
Tox21_110311_1 |
CS-4285 |
KS-1083 |
LP00720 |
NC00011 |
NSC 759578 |
NSC-759578 |
VA11204 |
NCGC00016160-01 |
NCGC00016160-03 |
NCGC00016160-04 |
NCGC00016160-05 |
NCGC00021145-11 |
NCGC00094068-01 |
NCGC00094068-02 |
NCGC00094068-03 |
NCGC00261405-01 |
O287 |
Succinic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine (1:1) |
Succinic acid, compound with 2-chloro-11-(4-methylpiperazin-1-yl)dibenz(b,f)(1,4)oxazepine (1:1) |
EU-0100720 |
FT-0653022 |
SW196603-4 |
VU0239541-8 |
D00794 |
F14786 |
833L643 |
SR-01000002971-2 |
SR-01000002971-6 |
SR-01000002971-9 |
W-107092 |
Q27107236 |
Loxapine succinate, United States Pharmacopeia (USP) Reference Standard |
(E)-2-chloro-11-(4-methylpiperazin-1-yl)dibenzob,f1,4oxazepine succinate |
Experimental Data
Loxapine succinate
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 43.000000000000000 | S | N2 | 33683565 | Active | ||||||
| Caenorhabditis elegans | 88.000000000000000 | umol/L | 43.000000000000000 | S | N2 | 24134630 | Active |
Experimental Data Visualization
Loxapine succinate
Statistics Data
Loxapine succinate
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 43.000000000000000 | 2 | 2 |
Statistics Data Visualization
Loxapine succinate
