Compound Summary
Loperamide hydrochloride
Compound Information
Loperamide hydrochloride
Compound Name: | Loperamide hydrochloride |
Compound CID: | 71420 |
Synonyms: | Loperamide hydrochloride 34552-83-5 Loperamide HCl Imodium Suprasec More... |
Iupac Name: | 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride |
InChI: | InChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H |
InChIKey: | PGYPOBZJRVSMDS-UHFFFAOYSA-N |
Canonical Smiles: | CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl |
Isomeric Smiles: | CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl |
Molecular Weight: | 513.5 |
Molecular Formula: | C29H34Cl2N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Loperamide hydrochloride
Molecular Weight: | 513.5 |
Molecular Formula: | C29H34Cl2N2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 35 |
Complexity: | 623 |
Synonyms
Loperamide hydrochloride
| Loperamide hydrochloride | Loperamide hydrochloride |
|---|---|
Loperamide hydrochloride |
34552-83-5 |
Loperamide HCl |
Imodium |
Suprasec |
Loperamide (hydrochloride) |
Fortasec |
Imodium A-D |
UNII-77TI35393C |
Maalox Anti-Diarrheal |
4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride |
4-4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride |
MLS000069779 |
CHEBI:6533 |
1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, hydrochloride |
MFCD00058581 |
4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidine butyramide HCl |
4-4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl-n,n-dimethyl-2,2-diphenylbutanamide;hydrochloride |
77TI35393C |
NSC-696356 |
4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenylpiperidine-1-butyramide monohydrochloride |
4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide monohydrochloride |
Dissenten |
Lopemid |
Lopemin |
Loperyl |
SMR000058466 |
Imosec |
Tebloc |
Maalox Antidiarrheal |
R 18,553 |
BLOX |
BREK |
Diamode |
Loseramin |
Imotil |
Anti-diarrheal |
Kao-Paverin |
Diar-Aid |
Kaopectate 1-D |
K-Pek II |
Pepto Diarrhea Control |
Imodium A-D EZ chews |
PJ185 |
SR-01000075507 |
Up and up anti diarrheal |
EINECS 252-082-4 |
C29H33ClN2O2.HCl |
C29H34Cl2N2O2 |
R-18553 |
Loperamide, HCl |
R 18553 |
Prestwick_302 |
Imodium (TN) |
CPD000058466 |
Loperamide hydrochloride USAN:USP:JAN |
Opera_ID_1508 |
4-(4-(p-Chlorophenyl)-4-hydroxy-1-piperidyl)-N,N-dimethyl-2,2-diphenylbutyramide HCl |
CHEMBL1707 |
LOPERAMIDEHYDROCHLORIDE |
SCHEMBL15048 |
R-18553 (hydrochloride) |
MLS001148627 |
MLS002222200 |
ARONIS27197 |
SPECTRUM2300241 |
REGID_for_CID_71420 |
Loperamide Hydrochloride ,(S) |
HY-B0418A |
Loperamide Hydrochloride Capsules |
DTXSID00880006 |
HMS1568M10 |
HMS1922J18 |
Pharmakon1600-02300241 |
BCP28441 |
Loperamide hydrochloride (JAN/USP) |
Tox21_500708 |
CCG-39494 |
NSC696356 |
NSC759568 |
s2480 |
AKOS015846351 |
AC-8242 |
ADL 2-1294 |
EBD2202345 |
LP00708 |
MCULE-8938403173 |
NC00572 |
NSC 759568 |
NSC-759568 |
NCGC00094059-01 |
NCGC00094059-02 |
NCGC00094059-03 |
NCGC00094059-04 |
NCGC00094059-05 |
NCGC00180886-01 |
NCGC00180886-02 |
NCGC00261393-01 |
1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, monohydrochloride |
4-4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride |
AS-13181 |
BL166178 |
H536 |
AB0013105 |
B1392 |
EU-0100708 |
FT-0627973 |
L0154 |
SW196602-3 |
D00729 |
D78217 |
L 4762 |
552L835 |
A822272 |
SR-01000075507-1 |
SR-01000075507-3 |
SR-01000075507-8 |
W-106729 |
Q27107231 |
Loperamide hydrochloride, VETRANAL(TM), analytical standard |
Loperamide hydrochloride, British Pharmacopoeia (BP) Reference Standard |
Loperamide hydrochloride, European Pharmacopoeia (EP) Reference Standard |
4-(4-Chlorophenyl)-4-hydroxy-N,.alpha.-diphenyl-1-piperidinebutanamide monohydrochloride |
4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-?,?-diphenyl-1-piperidinebutanamide hydrochloride |
Loperamide hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
Loperamide hydrochloride, United States Pharmacopeia (USP) Reference Standard |
4-(4-chlorophenyl)-1-4-(dimethylamino)-4-oxo-3,3-diphenylbutyl-4-hydroxypiperidin-1-ium chloride |
4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamidehydrochloride |
4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide hydrochloride |
4-4-(4-chlorophenyl)-4-oxidanyl-piperidin-1-yl-N,N-dimethyl-2,2-diphenyl-butanamide hydrochloride |
Loperamide hydrochloride for system suitability, European Pharmacopoeia (EP) Reference Standard |
Experimental Data
Loperamide hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 8.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Loperamide hydrochloride
Statistics Data
Loperamide hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 8.000000000000000 | 1 | 1 |
Statistics Data Visualization
Loperamide hydrochloride
