Compound Summary
Lomefloxacin hydrochloride
Compound Information
Lomefloxacin hydrochloride
Compound Name: | Lomefloxacin hydrochloride |
Compound CID: | 68624 |
Synonyms: | Lomefloxacin hydrochloride 98079-52-8 Lomefloxacin HCl Maxaquin Okacyn More... |
Iupac Name: | 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;hydrochloride |
InChI: | InChI=1S/C17H19F2N3O3.ClH/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);1H |
InChIKey: | KXEBLAPZMOQCKO-UHFFFAOYSA-N |
Canonical Smiles: | CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl |
Isomeric Smiles: | CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl |
Molecular Weight: | 387.8 |
Molecular Formula: | C17H20ClF2N3O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Lomefloxacin hydrochloride
Molecular Weight: | 387.8 |
Molecular Formula: | C17H20ClF2N3O3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 26 |
Complexity: | 586 |
Synonyms
Lomefloxacin hydrochloride
| Lomefloxacin hydrochloride | Lomefloxacin hydrochloride |
|---|---|
Lomefloxacin hydrochloride |
98079-52-8 |
Lomefloxacin HCl |
Maxaquin |
Okacyn |
Bareon |
Uniquin |
Ny-198 |
SC-47111 |
Lomefloxacin (hydrochloride) |
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride |
MFCD00214312 |
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;hydrochloride |
CHEBI:6518 |
Lomefloxacin hydrochloride (Maxaquin) |
Mazaquin |
DSSTox_CID_25527 |
DSSTox_RID_80931 |
DSSTox_GSID_45527 |
1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride |
Logiflox |
Okacin |
NY 198 |
(+-)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid monohydrochloride |
CCRIS 2581 |
SR-01000075959 |
Lomefloxacin hydrochloride USAN:JAN |
Lomefloxacin monohydrochloride |
Lomebact |
Maxaquine |
C17H20ClF2N3O3 |
C17H19F2N3O3.ClH |
Maxaquin (TN) |
Prestwick_581 |
NCGC00016964-01 |
NCGC00016964-02 |
CAS-98079-52-8 |
1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid |
CHEMBL1728 |
Lomefloxacin HCl (Maxaquin) |
SCHEMBL42051 |
(+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride |
SPECTRUM1502037 |
DTXSID2045527 |
HMS1568P17 |
HMS1921F20 |
Pharmakon1600-01502037 |
BCP12636 |
HY-B0455 |
Tox21_110716 |
Tox21_113154 |
Tox21_500678 |
2521AH |
CCG-39698 |
NSC758168 |
s2539 |
AKOS015895388 |
Tox21_110716_1 |
CM14476 |
CM14477 |
KS-1238 |
Lomefloxacin hydrochloride (JAN/USAN) |
LP00678 |
NSC 758168 |
NSC-758168 |
NCGC00015603-08 |
NCGC00094038-01 |
NCGC00094038-02 |
NCGC00094038-03 |
NCGC00261363-01 |
3-Quinolinecarboxylic acid, 1,4-dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride |
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride, (+-)- |
AC-32592 |
H534 |
DB-057707 |
EU-0100678 |
FT-0630997 |
L0216 |
C08053 |
D00873 |
L 2906 |
L-6500 |
O11839 |
079L528 |
A845801 |
A845802 |
A858587 |
TERT-BUTYL4-FLUORO-2-FORMYLPHENYLCARBAMATE |
SR-01000075959-1 |
SR-01000075959-5 |
Q27107226 |
Lomefloxacin monohydrochloride, Antibiotic for Culture Media Use Only |
1-ethyl-6,8-bis(fluoranyl)-7-(3-methylpiperazin-1-yl)-4-oxidanylidene-quinoline-3-carboxylic acid hydrochloride |
1-ethyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid hydrochloride |
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid hydrochloride;Lomefloxacin |
3-Quinolinecarboxylic acid,1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-,monohydrochloride |
Experimental Data
Lomefloxacin hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20.000000000000000 | umol/L | 44.630000000000000 | 44.120000000000000 | -1.150000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.170000000000000 | 42.530000000000000 | -1.482000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 16.190000000000000 | 16.420000000000000 | 1.443000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 17.370000000000000 | 17.480000000000000 | 0.634500000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 12.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Lomefloxacin hydrochloride
Statistics Data
Lomefloxacin hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 12.000000000000000 | 2 | 3 | |
| Drosophila melanogaster | -1.150000000000000 | 1 | 2 |
Statistics Data Visualization
Lomefloxacin hydrochloride
