Compound Summary
Lintitript
Compound Information
Lintitript
Compound Name: | Lintitript |
Compound CID: | 122077 |
Synonyms: | Lintitript SR 27897 136381-85-6 SR-27897 UNII-3YFV00531K More... |
Iupac Name: | 2-[2-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]acetic acid |
InChI: | InChI=1S/C20H14ClN3O3S/c21-14-7-3-2-6-13(14)15-11-28-20(22-15)23-19(27)17-9-12-5-1-4-8-16(12)24(17)10-18(25)26/h1-9,11H,10H2,(H,25,26)(H,22,23,27) |
InChIKey: | ILNRQFBVVQUOLP-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C2C(=C1)C=C(N2CC(=O)O)C(=O)NC3=NC(=CS3)C4=CC=CC=C4Cl |
Isomeric Smiles: | C1=CC=C2C(=C1)C=C(N2CC(=O)O)C(=O)NC3=NC(=CS3)C4=CC=CC=C4Cl |
Molecular Weight: | 411.9 |
Molecular Formula: | C20H14ClN3O3S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Lintitript
Molecular Weight: | 411.9 |
Molecular Formula: | C20H14ClN3O3S |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 28 |
Complexity: | 595 |
Synonyms
Lintitript
| Lintitript | Lintitript |
|---|---|
Lintitript |
SR 27897 |
136381-85-6 |
SR-27897 |
UNII-3YFV00531K |
SR27897 |
3YFV00531K |
2-2-4-(2-chlorophenyl)-1,3-thiazol-2-ylcarbamoylindol-1-ylacetic acid |
NCGC00167729-01 |
1H-Indole-1-acetic acid, 2-(((4-(2-chlorophenyl)-2-thiazolyl)amino)carbonyl)- |
2-(2-((4-(2-Chlorophenyl)thiazol-2-yl)carbamoyl)-1H-indol-1-yl)acetic acid |
DSSTox_CID_26738 |
DSSTox_RID_81867 |
DSSTox_GSID_46738 |
SR 27897 hydrate |
SR 27897B |
1H-Indole-1-acetic acid, 2-4-(2-chlorophenyl)-2-thiazolylaminocarbonyl- |
2-2-4-(2-chlorophenyl)-1,3-thiazol-2-ylcarbamoylindol-1-ylethanoic acid |
Lintitript INN |
CAS-136381-85-6 |
1-((2-(4-(2-Chlorophenyl)thiazol-2-yl)aminocarbonyl)indolyl)acetic acid |
ACMC-20engc |
2-((4-(o-Chlorophenyl)-2-thiazolyl)carbamoyl)indole-1-acetic acid |
SCHEMBL27123 |
GTPL890 |
CHEMBL249973 |
DTXSID9046738 |
BDBM82304 |
CHEBI:92624 |
HMS3268P15 |
HMS3413K13 |
HMS3677K13 |
HMS3742K11 |
ZINC537914 |
Tox21_112581 |
MFCD21608519 |
PDSP1_000946 |
PDSP2_000932 |
AKOS024456979 |
Tox21_112581_1 |
CAS_122077 |
CCG-221891 |
DB04867 |
NSC_122077 |
1H-Indole-1-aceticacid, 2-4-(2-chlorophenyl)-2-thiazolylaminocarbonyl- |
NCGC00167729-02 |
NCGC00167729-03 |
NCGC00167729-09 |
HY-101764 |
B6965 |
CS-0021860 |
FT-0753306 |
L000575 |
J-006840 |
BRD-K35629949-001-01-2 |
Q27080706 |
{2-4-(2-Chloro-phenyl)-thiazol-2-ylcarbamoyl-indol-1-yl}-acetic acid |
2-4-(2-Chlorophenyl)-2-thiazolylaminocarbonyl-1H-indole-1-acetic acid |
2-4-(2-chlorophenyl)-2-thiazolylaminocarbonyl-1H-indole-1-acetic acid hydrate |
1OE |
Experimental Data
Lintitript
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20.000000000000000 | umol/L | 44.630000000000000 | 45.900000000000000 | 2.840000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.170000000000000 | 45.670000000000000 | 5.797000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 16.600000000000000 | 16.670000000000000 | 0.431200000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 17.250000000000000 | 15.700000000000000 | -9.030000000000000 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
Lintitript
Statistics Data
Lintitript
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.431200000000000 | 1 | 2 | |
| Drosophila melanogaster | 5.797000000000000 | 1 | 2 |
Statistics Data Visualization
Lintitript
