Compound Summary
Linopirdine
Compound Information
Linopirdine
Compound Name: | Linopirdine |
Compound CID: | 3932 |
Synonyms: | Linopirdine 105431-72-9 Dup 996 1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one 1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one More... |
Iupac Name: | 1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one |
InChI: | InChI=1S/C26H21N3O/c30-25-26(18-20-10-14-27-15-11-20,19-21-12-16-28-17-13-21)23-8-4-5-9-24(23)29(25)22-6-2-1-3-7-22/h1-17H,18-19H2 |
InChIKey: | YEJCDKJIEMIWRQ-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C(C=C1)N2C3=CC=CC=C3C(C2=O)(CC4=CC=NC=C4)CC5=CC=NC=C5 |
Isomeric Smiles: | C1=CC=C(C=C1)N2C3=CC=CC=C3C(C2=O)(CC4=CC=NC=C4)CC5=CC=NC=C5 |
Molecular Weight: | 391.5 |
Molecular Formula: | C26H21N3O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Linopirdine
Molecular Weight: | 391.5 |
Molecular Formula: | C26H21N3O |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 30 |
Complexity: | 555 |
Synonyms
Linopirdine
| Linopirdine | Linopirdine |
|---|---|
Linopirdine |
105431-72-9 |
Dup 996 |
1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one |
1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one |
DuP-996 |
UNII-I5TB3NZ94T |
1-Phenyl-3,3-bis(pyridin-4-ylmethyl)indolin-2-one |
I5TB3NZ94T |
NCGC00015590-03 |
CHEBI:34823 |
DSSTox_CID_25163 |
DSSTox_RID_80713 |
DSSTox_GSID_45163 |
C26H21N3O |
Linopirine |
Linopirdine USAN:INN |
AVIVA |
CAS-105431-72-9 |
SR-01000075324 |
1-Phenyl-3,3-bis(4-pyridinylmethyl)-2-indolinone |
Tocris-1999 |
Lopac-L-134 |
Linopirdine (USAN/INN) |
2H-Indol-2-one, 1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)- |
1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one |
3,3-bis(4-pyridylmethyl)-1-phenylindolin-2-one |
Lopac0_000732 |
MLS000862189 |
SCHEMBL122699 |
DuP 996DuP 996 |
CHEMBL319111 |
GTPL2599 |
DTXSID6045163 |
Linopirdine, >=98% (HPLC) |
AOB5353 |
HMS2233C05 |
HMS3262C06 |
HMS3370B17 |
ZINC537908 |
Tox21_110177 |
Tox21_500732 |
MFCD00867216 |
Tox21_110177_1 |
CCG-204817 |
DB13806 |
HY-W020468 |
LP00732 |
SDCCGSBI-0050710.P002 |
NCGC00015590-01 |
NCGC00015590-02 |
NCGC00015590-04 |
NCGC00015590-05 |
NCGC00015590-06 |
NCGC00015590-07 |
NCGC00015590-10 |
NCGC00025338-01 |
NCGC00025338-02 |
NCGC00025338-03 |
NCGC00261417-01 |
AS-16868 |
SMR000326952 |
CS-0039654 |
EU-0100732 |
Y5884 |
D04741 |
W12323 |
3,3-Bis (4-pyridylmethyl)-1-phenylindolin-2-one |
3,3-bis(4-pyridinylmethyl)-1-phenylindolin-2-one |
Q6554730 |
SR-01000075324-1 |
BRD-K59332007-300-01-9 |
FCC |
Experimental Data
Linopirdine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -8.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Linopirdine
Statistics Data
Linopirdine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -8.000000000000000 | 1 | 1 |
Statistics Data Visualization
Linopirdine
