Compound Summary
LAPPAOL A
Compound Information
LAPPAOL A
Compound Name: | LAPPAOL A |
Compound CID: | 323894 |
Synonyms: | LAPPAOL A 62333-08-8 4-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-ylmethyl-3-(4-hydroxy-3-methoxyphenyl)methyloxolan-2-one 4-{2-(4-Hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-ylmethyl}-3-(4-hydroxy-3-methoxyphenyl)methyloxolan-2-one NSC287066 More... |
Iupac Name: | 4-[[2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one |
InChI: | InChI=1S/C30H32O9/c1-35-25-11-16(4-6-23(25)32)9-20-19(15-38-30(20)34)8-17-10-21-22(14-31)28(39-29(21)27(12-17)37-3)18-5-7-24(33)26(13-18)36-2/h4-7,10-13,19-20,22,28,31-33H,8-9,14-15H2,1-3H3 |
InChIKey: | PYLYQTVVQXPBIJ-UHFFFAOYSA-N |
Canonical Smiles: | COC1=CC(=CC2=C1OC(C2CO)C3=CC(=C(C=C3)O)OC)CC4COC(=O)C4CC5=CC(=C(C=C5)O)OC |
Isomeric Smiles: | COC1=CC(=CC2=C1OC(C2CO)C3=CC(=C(C=C3)O)OC)CC4COC(=O)C4CC5=CC(=C(C=C5)O)OC |
Molecular Weight: | 536.6 |
Molecular Formula: | C30H32O9 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
LAPPAOL A
Molecular Weight: | 536.6 |
Molecular Formula: | C30H32O9 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 9 |
Rotatable Bond Count: | 9 |
Heavy Atom Count: | 39 |
Complexity: | 809 |
Synonyms
LAPPAOL A
| LAPPAOL A | LAPPAOL A |
|---|---|
LAPPAOL A |
62333-08-8 |
4-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-ylmethyl-3-(4-hydroxy-3-methoxyphenyl)methyloxolan-2-one |
4-{2-(4-Hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-ylmethyl}-3-(4-hydroxy-3-methoxyphenyl)methyloxolan-2-one |
NSC287066 |
DTXSID20977886 |
NSC-287066 |
FT-0776969 |
Experimental Data
LAPPAOL A
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 200.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 6.200000000000000 | NS | N2 | 33683565 | Inactive | ||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 11.360000000000000 | 12.640000000000000 | 11.200000000000000 | S | N2 | 26141518 | Active | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 11.200000000000000 | S | N2 | 33683565 | Active | ||||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 11.360000000000000 | 12.060000000000000 | 6.200000000000000 | NS | N2 | 26141518 | Inactive |
Experimental Data Visualization
LAPPAOL A
Statistics Data
LAPPAOL A
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 11.200000000000000 | 2 | 8 |
Statistics Data Visualization
LAPPAOL A
