Compound Summary
L-leucine
Compound Information
L-leucine
Compound Name: | L-leucine |
Compound CID: | 6106 |
Synonyms: | L-leucine leucine 61-90-5 (S)-2-Amino-4-methylpentanoic acid (S)-Leucine More... |
Iupac Name: | (2S)-2-amino-4-methylpentanoic acid |
InChI: | InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 |
InChIKey: | ROHFNLRQFUQHCH-YFKPBYRVSA-N |
Canonical Smiles: | CC(C)CC(C(=O)O)N |
Isomeric Smiles: | CC(C)C[C@@H](C(=O)O)N |
Molecular Weight: | 131.17 |
Molecular Formula: | C6H13NO2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
L-leucine
Molecular Weight: | 131.17 |
Molecular Formula: | C6H13NO2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 9 |
Complexity: | 101 |
Synonyms
L-leucine
| L-leucine | L-leucine |
|---|---|
L-leucine |
leucine |
61-90-5 |
(S)-2-Amino-4-methylpentanoic acid |
(S)-Leucine |
H-Leu-OH |
(2S)-2-amino-4-methylpentanoic acid |
(S)-(+)-Leucine |
Leucin |
L-Norvaline, 4-methyl- |
(S)-2-Amino-4-methylvaleric acid |
L-alpha-Aminoisocaproic acid |
Leucin German |
leu |
Leucine (VAN) |
LEUCINE, L- |
Leucinum |
(2S)-alpha-leucine |
L-(+)-Leucine |
L-(-)-2-Amino-4-methylpentanoic acid |
L-leucin |
Leucine USAN:INN |
Leucinum INN-Latin |
Leucina INN-Spanish |
FEMA No. 3297 |
Leucina Latin,Spanish |
alpha-Aminoisocaproic acid |
Valeric acid, 2-amino-4-methyl-, (S)- |
2-amino-4-methylvaleric acid |
Pentanoic acid, 2-amino-4-methyl-, (S)- |
2-Amino-4-methylpentanoic acid, (S)- |
UNII-GMW67QNF9C |
L-Leuzin |
AI3-08899 |
2-Amino-4-methylvaleric acid (L) |
2-Amino-4-methylpentanoic acid (L) |
NSC 46709 |
(2S)-alpha-2-amino-4-methylvaleric acid |
MFCD00002617 |
GMW67QNF9C |
CHEMBL291962 |
L-Leucine, labeled with tritium |
CHEBI:15603 |
NSC-46709 |
Leucine (L-Leucine) |
L-Leu |
Leucina |
POLY-L-LEUCINE |
(2S)-2-amino-4-methylpentanoate |
L-a-Aminoisocaproic acid |
EINECS 200-522-0 |
HSDB 7799 |
LeuOH |
1lan |
1usk |
3h-l-leucine |
4-methyl-norvalin |
L-2-Amino-4-methylpentanoic acid |
L-Leucine; |
(L)-leucine |
.alpha.-Amino-.gamma.-methylvaleric acid |
(3H)Leucine |
alpha-Amino-gamma-methylvaleric acid |
H-Leu |
Leucine (USP) |
L-a-Aminoisocaproate |
4-methyl-l-norvalin |
L-Leucine,(S) |
Leucine (H-3) |
4-methyl-L-Norvaline |
L-Leu-OH |
(2S)-2-amino-4-methyl-pentanoic acid |
H-Leu-OH USP grade |
1f2o |
L-Leucine (JP17) |
L-alpha-Aminoisocaproate |
bmse000042 |
bmse000920 |
EC 200-522-0 |
L-Leucine, 99%, FG |
SCHEMBL3889 |
NCIStruc1_001860 |
NCIStruc2_000010 |
H-Leu-2-Chlorotrityl Resin |
iso-C4H9CH(NH2)COOH |
2-amino-4-methyl-valericaci |
2-amino-4-methylpentanoicacid |
2-Amino-4-methyl-valeric acid |
GTPL3312 |
L-.alpha.-Aminoisocaproic acid |
(S)-2-Amino-4-methylvalerate |
DTXSID9023203 |
Norvaline, 4-methyl-, (L)- |
L-Leucine, Cell Culture Reagent |
(S)-2-Amino-4-methylpentanoate |
(s)-2-amino-4-methylvalericacid |
Pharmakon1600-01301005 |
25322-63-8 |
HY-N0486 |
NCI46709 |
STR01720 |
ZINC3645145 |
L-Leucine, Vetec(TM), 98.5% |
BDBM50219348 |
CCG-37658 |
NCGC00013565 |
NSC760100 |
s3753 |
Oxirane, 2,3-bis(2-chlorophenyl)- |
(S)-2-Amino-4-methyl-pentanoic acid |
2-Amino-4-methylvaleric acid, (L)- |
AKOS010373766 |
AKOS015841779 |
AM81871 |
CS-W020705 |
DB00149 |
MCULE-4930237913 |
NSC-760100 |
2-Amino-4-methylpentanoic acid, (L)- |
L-Leucine, tested according to Ph.Eur. |
NCGC00013565-02 |
NCGC00096678-01 |
71000-80-1 |
E641 |
1-Leucine;2-Amino-4-methylpentanoic acid |
L-Leucine, BioUltra, >=99.5% (NT) |
AB0011442 |
DB-029966 |
L-Leucine, SAJ special grade, >=99.0% |
BB 0256932 |
L-Leucine, reagent grade, >=98% (HPLC) |
L0029 |
L-Leucine, Vetec(TM) reagent grade, >=98% |
C00123 |
D00030 |
L-2700 |
M03060 |
(2S)-2-azaniumyl-4-methyl-pentanoate;H-Leu-OH |
34147-EP2289892A1 |
34147-EP2301939A1 |
34147-EP2305825A1 |
34147-EP2311850A1 |
002L617 |
A821449 |
A833479 |
Q483745 |
Q-201312 |
(2R)-2-amino-4-methyl-pentanoic acid;D-HOMO-VALINE |
L-Leucine, certified reference material, TraceCERT(R) |
2B9FF792-3CA1-4BEA-BC63-6D4E1A86714E |
F8889-8638 |
Leucine, European Pharmacopoeia (EP) Reference Standard |
Z1250208667 |
UNII-0O72R8RF8A component ROHFNLRQFUQHCH-YFKPBYRVSA-N |
UNII-1QSS9D5DR6 component ROHFNLRQFUQHCH-YFKPBYRVSA-N |
UNII-66PZQ62YA6 component ROHFNLRQFUQHCH-YFKPBYRVSA-N |
UNII-N7U7BXP2OI component ROHFNLRQFUQHCH-YFKPBYRVSA-N |
L-Leucine, United States Pharmacopeia (USP) Reference Standard |
(S)-2-Amino-4-methyl-pentanoic acid methyl ester hydrochloride |
L-Leucine, Pharmaceutical Secondary Standard; Certified Reference Material |
L-Leucine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0% |
L-Leucine, PharmaGrade, Ajinomoto, EP, JP, USP, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture |
Experimental Data
L-leucine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 5.000000000000000 | mM | 25.300000000000000 | 27.030000000000000 | 0.070000000000000 | 27.300000000000000 | 29.300000000000000 | 0.070000000000000 | S | N2 | 26620638 | Active | |
| Caenorhabditis elegans | 5.000000000000000 | mM | 6.000000000000000 | S | N2 | 25643626 | Active | ||||||
| Caenorhabditis elegans | 1.000000000000000 | mM | 16.000000000000000 | S | N2 | 25643626 | Active | ||||||
| Caenorhabditis elegans | 10.000000000000000 | mM | 7.000000000000000 | S | N2 | 25643626 | Active |
Experimental Data Visualization
L-leucine
Statistics Data
L-leucine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 16.000000000000000 | 0.070000000000000 | 2 | 4 |
Statistics Data Visualization
L-leucine
