Compound Summary
L-745,870 hydrochloride
Compound Information
L-745,870 hydrochloride
Compound Name: | L-745,870 hydrochloride |
Compound CID: | 11957618 |
Synonyms: | L-745,870 hydrochloride 1173023-36-3 L-745870 hydrochloride UNII-X2UD7T27FU X2UD7T27FU More... |
Iupac Name: | 3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine;hydrochloride |
InChI: | InChI=1S/C18H19ClN4.ClH/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18;/h1-7,12H,8-11,13H2,(H,20,21);1H |
InChIKey: | GFFJYISJZJIKAF-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CCN1CC2=CNC3=C2C=CC=N3)C4=CC=C(C=C4)Cl.Cl |
Isomeric Smiles: | C1CN(CCN1CC2=CNC3=C2C=CC=N3)C4=CC=C(C=C4)Cl.Cl |
Molecular Weight: | 363.3 |
Molecular Formula: | C18H20Cl2N4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
L-745,870 hydrochloride
Molecular Weight: | 363.3 |
Molecular Formula: | C18H20Cl2N4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 24 |
Complexity: | 377 |
Synonyms
L-745,870 hydrochloride
| L-745,870 hydrochloride | L-745,870 hydrochloride |
|---|---|
L-745,870 hydrochloride |
1173023-36-3 |
L-745870 hydrochloride |
UNII-X2UD7T27FU |
X2UD7T27FU |
L-745870 (hydrochloride) |
CHEMBL555670 |
3-((4-(4-Chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo2,3-bpyridine hydrochloride |
NCGC00094126-01 |
3-4-(4-Chlorophenyl)piperazin-1-ylmethyl-1H-pyrrolo2,3-bpyridine hydrochloride |
3-4-(4-chlorophenyl)piperazin-1-ylmethyl-1H-pyrrolo2,3-bpyridine;hydrochloride |
SR-01000075388 |
EU-0100791 |
MLS002153286 |
DTXSID101016928 |
Tox21_500791 |
HY-14325B |
CCG-222095 |
LP00791 |
NCGC00261476-01 |
SMR001230711 |
CS-0109248 |
L-131 |
SR-01000075388-1 |
3-((4-(4-Chlorophenyl)-1-piperazinyl)methyl)-1H-pyrrolo(2,3-b)pyridine hydrochloride |
1H-Pyrrolo(2,3-b)pyridine, 3-((4-(4-chlorophenyl)-1-piperazinyl)methyl)-, hydrochloride (1:1) |
Experimental Data
L-745,870 hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -25.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
L-745,870 hydrochloride
Statistics Data
L-745,870 hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -25.000000000000000 | 1 | 1 |
Statistics Data Visualization
L-745,870 hydrochloride
