Compound Summary
L-733,060 hydrochloride
Compound Information
L-733,060 hydrochloride
Compound Name: | L-733,060 hydrochloride |
Compound CID: | 11957600 |
Synonyms: | L-733,060 hydrochloride L-733060 (hydrochloride) NCGC00094093-01 148687-76-7 L-733,060 More... |
Iupac Name: | (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine;hydrochloride |
InChI: | InChI=1S/C20H19F6NO.ClH/c21-19(22,23)15-9-13(10-16(11-15)20(24,25)26)12-28-17-7-4-8-27-18(17)14-5-2-1-3-6-14;/h1-3,5-6,9-11,17-18,27H,4,7-8,12H2;1H/t17-,18-;/m0./s1 |
InChIKey: | DYEUTIUITGHIEO-APTPAJQOSA-N |
Canonical Smiles: | C1CC(C(NC1)C2=CC=CC=C2)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F.Cl |
Isomeric Smiles: | C1C[C@@H]([C@@H](NC1)C2=CC=CC=C2)OCC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F.Cl |
Molecular Weight: | 439.8 |
Molecular Formula: | C20H20ClF6NO |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
L-733,060 hydrochloride
Molecular Weight: | 439.8 |
Molecular Formula: | C20H20ClF6NO |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 29 |
Complexity: | 466 |
Synonyms
L-733,060 hydrochloride
| L-733,060 hydrochloride | L-733,060 hydrochloride |
|---|---|
L-733,060 hydrochloride |
L-733060 (hydrochloride) |
NCGC00094093-01 |
148687-76-7 |
L-733,060 |
(2S,3S)-3-3,5-BIS(TRIFLUOROMETHYL)PHENYLMETHOXY-2-PHENYLPIPERIDINE HYDROCHLORIDE |
3-(3,5-BIS(TRIFLUOROMETHYL)PHENYLMETHOXY)-2-PHENYL-PIPERIDINE HYDROCHLORIDE |
EU-0100752 |
SCHEMBL4297874 |
CHEMBL1256740 |
HMS3412M11 |
HMS3676M11 |
HY-14406A |
AKOS024456415 |
CS-0021289 |
L-137 |
SR-01000075974 |
SR-01000597889 |
SR-01000075974-1 |
SR-01000597889-1 |
(+)-cis-3((3,5- Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine hydrochloride salt |
(2S,3S) 3-(3,5-Bis(trifluoromethyl)phenylmethoxy)-2-phenylpiperidine hydrochloride |
(2s,3s)-3-3,5-bis(trifluoromethyl)phenyl-methoxy-2-phenyl-piperidine hydrochloride |
Experimental Data
L-733,060 hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -39.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
L-733,060 hydrochloride
Statistics Data
L-733,060 hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -39.000000000000000 | 1 | 1 |
Statistics Data Visualization
L-733,060 hydrochloride
