Compound Summary
L-368,899
Compound Information
L-368,899
Compound Name: | L-368,899 |
Compound CID: | 11957584 |
Synonyms: | L-368,899 EU-0100668 NCGC00094029-01 MLS002172442 CHEMBL1450525 More... |
Iupac Name: | (2S)-2-amino-N-[(1S)-7,7-dimethyl-1-[[4-(2-methylphenyl)piperazin-1-yl]sulfonylmethyl]-2-bicyclo[2.2.1]heptanyl]-4-methylsulfonylbutanamide;hydrochloride |
InChI: | InChI=1S/C26H42N4O5S2.ClH/c1-19-7-5-6-8-22(19)29-12-14-30(15-13-29)37(34,35)18-26-11-9-20(25(26,2)3)17-23(26)28-24(31)21(27)10-16-36(4,32)33;/h5-8,20-21,23H,9-18,27H2,1-4H3,(H,28,31);1H/t20?,21-,23?,26+;/m0./s1 |
InChIKey: | GIUFQWFJHXXXEQ-SVFGMJTMSA-N |
Canonical Smiles: | CC1=CC=CC=C1N2CCN(CC2)S(=O)(=O)CC34CCC(C3(C)C)CC4NC(=O)C(CCS(=O)(=O)C)N.Cl |
Isomeric Smiles: | CC1=CC=CC=C1N2CCN(CC2)S(=O)(=O)C[C@@]34CCC(C3(C)C)CC4NC(=O)[C@H](CCS(=O)(=O)C)N.Cl |
Molecular Weight: | 591.2 |
Molecular Formula: | C26H43ClN4O5S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
L-368,899
Molecular Weight: | 591.2 |
Molecular Formula: | C26H43ClN4O5S2 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 9 |
Heavy Atom Count: | 38 |
Complexity: | 1040 |
Synonyms
L-368,899
| L-368,899 | L-368,899 |
|---|---|
L-368,899 |
EU-0100668 |
NCGC00094029-01 |
MLS002172442 |
CHEMBL1450525 |
1-((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo2,2,1heptan-1(S)-yl)methylsulfonyl)-4-(2-methylphenyl)piperazine hydrochloride |
SMR001254079 |
L 2540 |
SR-01000076223 |
SR-01000076223-1 |
Experimental Data
L-368,899
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -1.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
L-368,899
Statistics Data
L-368,899
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -1.000000000000000 | 1 | 1 |
Statistics Data Visualization
L-368,899
