Compound Summary
JHW 007 Hydrochloride
Compound Information
JHW 007 Hydrochloride
Compound Name: | JHW 007 Hydrochloride |
Compound CID: | 71771746 |
Synonyms: | JHW 007 Hydrochloride 202645-74-7 (1S,5R)-3-bis(4-fluorophenyl)methoxy-8-butyl-8-azabicyclo3.2.1octane;hydrochloride AKOS024458110 (3-endo)-3-Bis(4-fluorophenyl)methoxy-8-butyl-8-azabicyclo3.2.1octane hydrochloride More... |
Iupac Name: | (1S,5R)-3-[bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane;hydrochloride |
InChI: | InChI=1S/C24H29F2NO.ClH/c1-2-3-14-27-21-12-13-22(27)16-23(15-21)28-24(17-4-8-19(25)9-5-17)18-6-10-20(26)11-7-18;/h4-11,21-24H,2-3,12-16H2,1H3;1H/t21-,22+,23?; |
InChIKey: | RHYMGBAYGRUKNZ-DHWZJIOFSA-N |
Canonical Smiles: | CCCCN1C2CCC1CC(C2)OC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl |
Isomeric Smiles: | CCCCN1[C@@H]2CC[C@H]1CC(C2)OC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl |
Molecular Weight: | 421.9 |
Molecular Formula: | C24H30ClF2NO |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
JHW 007 Hydrochloride
Molecular Weight: | 421.9 |
Molecular Formula: | C24H30ClF2NO |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 29 |
Complexity: | 437 |
Synonyms
JHW 007 Hydrochloride
| JHW 007 Hydrochloride | JHW 007 Hydrochloride |
|---|---|
JHW 007 Hydrochloride |
202645-74-7 |
(1S,5R)-3-bis(4-fluorophenyl)methoxy-8-butyl-8-azabicyclo3.2.1octane;hydrochloride |
AKOS024458110 |
(3-endo)-3-Bis(4-fluorophenyl)methoxy-8-butyl-8-azabicyclo3.2.1octane hydrochloride |
Experimental Data
JHW 007 Hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -25.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
JHW 007 Hydrochloride
Statistics Data
JHW 007 Hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -25.000000000000000 | 1 | 1 |
Statistics Data Visualization
JHW 007 Hydrochloride
