Compound Summary
Isoxanthohumol
Compound Information
Isoxanthohumol
Compound Name: | Isoxanthohumol |
Compound CID: | 513197 |
Synonyms: | Isoxanthohumol 521-48-2 Isoxanthohumol(Sophora) 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one CHEMBL492828 More... |
Iupac Name: | 7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one |
InChI: | InChI=1S/C21H22O5/c1-12(2)4-9-15-16(23)10-19(25-3)20-17(24)11-18(26-21(15)20)13-5-7-14(22)8-6-13/h4-8,10,18,22-23H,9,11H2,1-3H3 |
InChIKey: | YKGCBLWILMDSAV-UHFFFAOYSA-N |
Canonical Smiles: | CC(=CCC1=C2C(=C(C=C1O)OC)C(=O)CC(O2)C3=CC=C(C=C3)O)C |
Isomeric Smiles: | CC(=CCC1=C2C(=C(C=C1O)OC)C(=O)CC(O2)C3=CC=C(C=C3)O)C |
Molecular Weight: | 354.4 |
Molecular Formula: | C21H22O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Isoxanthohumol
Molecular Weight: | 354.4 |
Molecular Formula: | C21H22O5 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 26 |
Complexity: | 519 |
Synonyms
Isoxanthohumol
| Isoxanthohumol | Isoxanthohumol |
|---|---|
Isoxanthohumol |
521-48-2 |
Isoxanthohumol(Sophora) |
7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one |
CHEMBL492828 |
7-Hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one |
5-Methylsophoraflavanone B |
Isoxanthohumol, HPLC Grade |
SCHEMBL904557 |
CHEBI:171798 |
Isoxanthohumol, >=99% (HPLC) |
Isoxanthohumol, analytical standard |
(2S)-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one |
BCP23864 |
BDBM50252521 |
LMPK12140553 |
MFCD00238718 |
SMP2_000215 |
NCGC00390429-01 |
4,7-dihydroxy-5-methoxy-8-prenylflavanone" |
4,7-dihydroxy-5-methoxy-8-c-prenylflavanone |
Q6086616 |
Isoxanthohumol, primary pharmaceutical reference standard |
7-hydroxy-2-(4-hydroxy-phenyl)-5-methoxy-8-(3-methyl-but-2-enyl)-chroman-4-one |
7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)chroman-4-one |
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)- |
7-Hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-2,3-dihydro-4H-chromen-4-one # |
Experimental Data
Isoxanthohumol
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 200.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 200.000000000000000 | umol/L | -2.080000000000000 | NS | N2 | 33683565 | Inactive | ||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 2.430000000000000 | NS | N2 | 33683565 | Inactive |
Experimental Data Visualization
Isoxanthohumol
Statistics Data
Isoxanthohumol
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2.430000000000000 | 1 | 6 |
Statistics Data Visualization
Isoxanthohumol
