Compound Summary
IMS2186
Compound Information
IMS2186
Compound Name: | IMS2186 |
Compound CID: | 24987039 |
Synonyms: | IMS2186 1031206-36-6 IMS 2186 3-1-(3-Hydroxy-4-methoxyphenyl)-meth-(E)-ylidene-6-methyl-chroman-4-one SCHEMBL4732781 More... |
Iupac Name: | (3E)-3-[(3-hydroxy-4-methoxyphenyl)methylidene]-6-methylchromen-4-one |
InChI: | InChI=1S/C18H16O4/c1-11-3-5-16-14(7-11)18(20)13(10-22-16)8-12-4-6-17(21-2)15(19)9-12/h3-9,19H,10H2,1-2H3/b13-8+ |
InChIKey: | BZCADTHMZLYKAR-MDWZMJQESA-N |
Canonical Smiles: | CC1=CC2=C(C=C1)OCC(=CC3=CC(=C(C=C3)OC)O)C2=O |
Isomeric Smiles: | CC1=CC2=C(C=C1)OC/C(=C\C3=CC(=C(C=C3)OC)O)/C2=O |
Molecular Weight: | 296.3 |
Molecular Formula: | C18H16O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
IMS2186
Molecular Weight: | 296.3 |
Molecular Formula: | C18H16O4 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 22 |
Complexity: | 444 |
Synonyms
IMS2186
| IMS2186 | IMS2186 |
|---|---|
IMS2186 |
1031206-36-6 |
IMS 2186 |
3-1-(3-Hydroxy-4-methoxyphenyl)-meth-(E)-ylidene-6-methyl-chroman-4-one |
SCHEMBL4732781 |
HMS3263I22 |
Tox21_501090 |
ZINC44018876 |
CCG-222394 |
LP01090 |
SDCCGSBI-0633787.P001 |
NCGC00261775-01 |
NCGC00386646-03 |
IMS2186, >=98% (HPLC), solid |
J-000877 |
(E)-3-(3-hydroxy-4-methoxybenzylidene)-6-methylchroman-4-one |
(3E)-3-(3-hydroxy-4-methoxyphenyl)methylidene-6-methylchromen-4-one |
(3E)-2,3-Dihydro-3-(3-hydroxy-4-methoxyphenyl)methylene-6-methyl-4H-1-benzopyran-4-one |
Experimental Data
IMS2186
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 17.760000000000000 | 16.020000000000000 | -9.809000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 49.360000000000000 | 48.880000000000000 | -0.969300000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 45.820000000000000 | 41.220000000000000 | -10.040000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 16.580000000000000 | 15.710000000000000 | -5.201000000000000 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
IMS2186
Statistics Data
IMS2186
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5.201000000000000 | 1 | 2 | |
| Drosophila melanogaster | -0.969300000000000 | 1 | 2 |
Statistics Data Visualization
IMS2186
