Compound Summary
I-OMe-Tyrphostin AG 538
Compound Information
I-OMe-Tyrphostin AG 538
Compound Name: | I-OMe-Tyrphostin AG 538 |
Compound CID: | 5353685 |
Synonyms: | I-OMe-Tyrphostin AG 538 MLS002153417 (E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile SMR001230793 Tyrphostin I-OMe-AG 538 More... |
Iupac Name: | (E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile |
InChI: | InChI=1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+ |
InChIKey: | HSRMHXWCTRFVHK-NYYWCZLTSA-N |
Canonical Smiles: | COC1=C(C(=CC(=C1)C=C(C#N)C(=O)C2=CC(=C(C=C2)O)O)I)O |
Isomeric Smiles: | COC1=C(C(=CC(=C1)/C=C(\C#N)/C(=O)C2=CC(=C(C=C2)O)O)I)O |
Molecular Weight: | 437.18 |
Molecular Formula: | C17H12INO5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
I-OMe-Tyrphostin AG 538
Molecular Weight: | 437.18 |
Molecular Formula: | C17H12INO5 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 24 |
Complexity: | 542 |
Synonyms
I-OMe-Tyrphostin AG 538
| I-OMe-Tyrphostin AG 538 | I-OMe-Tyrphostin AG 538 |
|---|---|
I-OMe-Tyrphostin AG 538 |
MLS002153417 |
(E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile |
SMR001230793 |
Tyrphostin I-OMe-AG 538 |
1094048-77-7 |
NCGC00016053-01 |
Lopac-T-7697 |
Lopac0_001251 |
CHEMBL1257003 |
SCHEMBL18045514 |
SCHEMBL18045517 |
BDBM60983 |
CHEBI:92618 |
cid_5353685 |
DTXSID401016927 |
HMS2233K08 |
HMS3263L04 |
I-OMe-Tyrphostin AG 538, solid |
ZINC3872925 |
Tox21_501251 |
HSCI1_000133 |
CCG-205325 |
LP01251 |
SDCCGSBI-0051218.P002 |
alpha-Cyano-(3-methoxy,4-hydroxy,5-iodo)cinnamoyl-(3′,4′-dihydroxyphenyl)ketone |
NCGC00016053-02 |
NCGC00016053-03 |
NCGC00016053-04 |
NCGC00016053-06 |
NCGC00094491-01 |
NCGC00094491-02 |
NCGC00261936-01 |
HY-135680 |
CS-0113753 |
EU-0101251 |
T 7697 |
SR-01000076177 |
SR-01000076177-1 |
(E)-3-(4-hydroxy-3-iodo-5-methoxy-phenyl)-2-protocatechuoyl-acrylonitrile |
(2E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile |
alpha-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3,4-dihydroxyphenyl)ketone |
(E)-2-(3,4-dihydroxyphenyl)-oxomethyl-3-(4-hydroxy-3-iodo-5-methoxyphenyl)-2-propenenitrile |
(E)-2-3,4-bis(oxidanyl)phenylcarbonyl-3-(3-iodanyl-5-methoxy-4-oxidanyl-phenyl)prop-2-enenitrile |
Experimental Data
I-OMe-Tyrphostin AG 538
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 10.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
I-OMe-Tyrphostin AG 538
Statistics Data
I-OMe-Tyrphostin AG 538
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | 1 | 1 |
Statistics Data Visualization
I-OMe-Tyrphostin AG 538
