Compound Summary
Huperzine A
Compound Information
Huperzine A
Compound Name: | Huperzine A |
Compound CID: | 449069 |
Synonyms: | Huperzine A (-)-huperzine A 102518-79-6 Selagine LSM-5567 More... |
Iupac Name: | (1R,9R)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one |
InChI: | InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/t10-,15+/m0/s1 |
InChIKey: | ZRJBHWIHUMBLCN-ZUZCIYMTSA-N |
Canonical Smiles: | CC=C1C2CC3=C(C1(CC(=C2)C)N)C=CC(=O)N3 |
Isomeric Smiles: | CC=C1[C@@H]2CC3=C([C@]1(CC(=C2)C)N)C=CC(=O)N3 |
Molecular Weight: | 242.32 |
Molecular Formula: | C15H18N2O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Huperzine A
Molecular Weight: | 242.32 |
Molecular Formula: | C15H18N2O |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 18 |
Complexity: | 551 |
Synonyms
Huperzine A
| Huperzine A | Huperzine A |
|---|---|
Huperzine A |
(-)-huperzine A |
102518-79-6 |
Selagine |
LSM-5567 |
(-)-Huperzine |
(-)- HUPPERZINE A |
Fordine |
120786-18-7 |
C15H18N2O |
Huperzine A; |
92138-20-0 |
SR-01000781266 |
Isoselagine |
HupA |
(-)-huperazine A; |
Spectrum2_000835 |
Spectrum3_001074 |
Spectrum4_001229 |
Spectrum5_001701 |
BSPBio_002688 |
KBioGR_001698 |
MLS001424307 |
SPBio_000789 |
CHEMBL4515144 |
SCHEMBL16789797 |
BCBcMAP01_000072 |
KBio3_001908 |
EX-A282 |
HMS2052D07 |
BCP08891 |
AC-488 |
CCG-101168 |
NC00418 |
SMP1_000153 |
SMR000469231 |
FT-0627095 |
18H796 |
C90354 |
SR-01000781266-3 |
SR-01000781266-4 |
Q27166443 |
(1R,9R,13Z)-1-Amino-13-ethylidene-11-methyl-6-azatricyclo7.3.1.02,7trideca-2(7),3,10-trien-5-one |
(1R,9S,13E)-1-Amino-13-ethylidene-11-methyl-6-azatricyclo7.3.1.02,7trideca-2(7),3,10-trien-5-one |
Experimental Data
Huperzine A
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 300.000000000000000 | umol/L | 12.000000000000000 | 13.500000000000000 | 0.120000000000000 | S | N2 | 23523941 | Active |
Experimental Data Visualization
Huperzine A
Statistics Data
Huperzine A
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.120000000000000 | 1 | 1 |
Statistics Data Visualization
Huperzine A
